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Xenical is used to help people lose weight and maintain weight loss while eating a reduced-calorie diet. This medicine decreases the amount of fat that is absorbed from your diet.

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Also known as: Orlistat


Xenical (orlistat) blocks some of the fat that you eat, keeping it from being absorbed by your body.

Xenical is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet and is to used only by adults.

Xenical is the prescription-strength form of orlistat. The alli brand of orlistat is available without a prescription.


Xenical capsule should be swallowed with water. Take one capsule orally 3 times a day during the main meal or up to 1 hour after the meal. The diet of the patient should include three main meals, containing the daily dose of fat, carbohydrate, and protein. The daily intake of fat should be no more than 30% of your total daily caloric intake (e.g., eating 1200 calories per day, no more than 360 of those calories should be in the form of fat) while taking Xenical. The dose of Xenical should be omitted if a meal is missed or does not contain fat. Treatment with Xenical should not continue for more than 6 months and should be stopped after 12 weeks if patient has been unable to lose at least 5 % of the body weight. Xenical is approved to be taken along with nutritionally balanced, low-calorie diet and physical activity. Xenical can be used by people with diabetes, high blood pressure, heart disease or high cholesterol. Precautions: Xenical is intended for use only in adults and can be dangerous for children. Do not stop taking Xenical suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Xenical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Xenical if you are allergic to orlistat, or if you have malabsorption syndrome (an inability to absorb food and nutrients properly).

You also should not use this medicine if you have:

gallbladder problems; or if you are pregnant.

Do not use alli if:

you are not overweight; you have had an organ transplant; or you use cyclosporine (to prevent organ transplant rejection).

To make sure Xenical is safe for you, tell your doctor if you have ever had:

kidney stones; gallbladder disease; pancreatitis; underactive thyroid; liver disease; kidney disease; or an eating disorder (anorexia or bulimia).

Do not use Xenical if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight. Stop taking orlistat and tell your doctor right away if you become pregnant.

Taking orlistat can make it harder for your body to absorb certain vitamins. These vitamins are important if you are nursing a baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Xenical is not approved for use by anyone younger than 12 years old. Do not give alli to anyone under 18 years old.

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