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Requip (Ropinirole)

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Requip is a medication used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). In PD the dose needs to be adjusted to the effect and treatment should not be suddenly stopped. It is taken by mouth.

Other names for this medication:
Parkirop, Ropark, Ropeway, Ropin, Ropinirole, Ropitor

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Also known as: Ropinirole


Requip (ropinirole) is a dopaminergic agent and it has some of the same effects as dopamine, a naturally occuring chemical found in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Requip is used to treat symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control). Ropinirole is also used to treat restless legs syndrome (RLS).

Only immediate-release Requip is approved to treat either Parkinson symptoms or RLS. Extended-release Requip XL is approved only to treat Parkinson symptoms.

Parkinson's and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.


Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.

If you are taking immediate-release Requip XL (Requip) you should not take extended-release this medicine (Requip XL) at the same time.

The dose and timing of ropinirole in treating Parkinson's disease is different from the dose and timing in treating RLS. Follow the directions on your prescription label. Ask your pharmacist if you have any questions about the kind of ropinirole you receive at the pharmacy.

Requip XL can be taken with or without food. Take the medicine at the same time each day.

Do not crush, chew, or break an extended-release tablet (Requip XL). Swallow it whole.

Call your doctor if you see part of the Requip XL tablet in your stool. This is a sign that your body may not have absorbed all of the medicine.

If you are taking this medicine for RLS, tell your doctor if your symptoms get worse, if they occur in the morning or earlier than usual in the evening, or if you feel restless symptoms in your hands or arms.

It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Do not stop using Requip XL suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Requip XL dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Requip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Requip if you are allergic to ropinirole.

To make sure Requip is safe for you, tell your doctor if you have:

high or low blood pressure; kidney disease (or if you are on dialysis); heart disease, heart rhythm problems; a sleep disorder such as narcolepsy, or other conditions that may cause daytime sleepiness; or if you smoke.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.

It is not known whether Requip will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether ropinirole passes into breast milk or if it could affect the nursing baby. Ropinirole may slow breast milk production. Tell your doctor if you are breast-feeding.

Requip is not approved for use by anyone younger than 18 years old.

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Homeless children: Experiences and meanings of the environments they construct. It is possible to take detailed family histories and provide genetic counselling advice in primary care with minimal training of clinical primary care staff. In this paper, we studied the choice of ants when facing either a symmetrical or an asymmetrical bifurcation between two tunnels. Systemic treatment in advanced soft tissue sarcoma: what is standard, what is new. The results suggest that the permanent deformation of wrought-wire clasps is likely to initiate at the clasp shoulder, while clasp flexibility is dependent on the bending angle of the clasp arm. Between August 2005 and July 2006, 2 men and 15 women aged 74 to 94 (mean, 85) years with proximal femoral fractures underwent open reduction and internal fixation using the twin hook system. Inh3 was not degraded in apoptotic MCF-7 cells, which lack caspase-3. Emission from both neutral and charged exciton complexes was observed with their relative intensites depending on the injection current and temperature. Activation of vasopressinergic neurosecretory cells at administration of the blocker Bcl-2 HA14-1 was shown: there were observed an increase of vasopressin mRNA in neurons of hypothalamus supraoptical and paraventricular nuclei, a decrease of the immunoreactive vasopressin content in posterior pituitary, and reduction of diuresis.

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Radiological study of the temporal bone by the direct enlargement method. Effects of EGCG on voltage-gated sodium channels in primary cultures of rat hippocampal CA1 neurons. Harmonization and standardization of results among different clinical laboratories is necessary for clinical practice guidelines to be established. Whereas different markers peaked coordinately, the time to peak varied across TBI cases from 24-96 h post-injury. Acetylation of MKL1 by PCAF regulates pro-inflammatory transcription. A statistically significant difference of E was found at 1, 3, 6 and 24 months.

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Clone, prokaryotic expression and preparation of polyclonal antibody of hCD59. Improved outcomes with endovascular stent grafts for thoracic aorta transections. These results suggest that acute HBOT after hepatectomy, aimed at reducing perioperative erythrocyte transfusions, may be employed for overcoming deficiencies in systemic and hepatic oxygen supply and thus diminishing postoperative complications. This paper considers how partial and comprehensive smokefree policies affected bar and restaurant revenue, using quarterly data reported to the Minnesota Department of Revenue. The aim of this study was to assess the long-term effect of gonadotropin-releasing hormone analogues (GnRH-a) in combination with high-dose progestogens in the treatment of atypical endometrial hyperplasia in zofran medication price selected surgical high-risk patients and in women desiring reproductive potential. Compared with single MoS2, LDH/MoS2 hybrids showed a more homogeneous dispersion in the epoxy matrix and no obvious agglomerates were observed. Both hemorrhage and melanin can produce T1-weighted hyperintensity and T2-weighted signal intensity loss.

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Individual differences in overextincation of the SCR component of the orienting response. To detect association of the DR1 allele with rheumatoid arthritis (RA) given linkage in the affected sibling pairs of the replicates of Problem 3 of Genetic Analysis Workshop 15 (GAW15), we propose a new score statistic that takes into account the linkage information. The biosynthesis of estriol-3,16-disulfate by guinea pig liver homogenate. To report a case of corneal perforation secondary to Acanthamoeba and fungal keratitis in a patient with a history of Intacs corneal implants. This mutation was associated with incomplete penetrance and variable age of onset. An overall structural similarity between the protein molecules in the two crystal forms is suggested by the projection maps. Unlike guidance cues, the molecules and signaling cascades that underlie axonal branching remain to be resolved. The results suggest the importance of these transient risk factors, particularly floor contamination, on rate of slipping in limited-service restaurant workers. The use of X-ray spectroscopic techniques to detect minute differences in atomic structure and bonding in complex nanosystems makes it possible to better understand and predict catalytic or magnetic properties for nanoscale bimetallic hybrid materials.

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Intrapleural instillation of quinacrine for recurrent pneumothorax. Synovial fluid levels of tumour necrosis factor-alpha (TNFalpha) and interleukin-6 (IL-6) of AS peripheral joints were measured using an enzyme-linked immunosorbent assay (ELISA). Moreover, in a murine CML model, ACF decreased leukemia development and reduced LSC maintenance. Based on the research history of the biomechanics of occipito-atlantoaxial complex, we have systematically summarized the use of finite element prilosec otc 20 mg side effects method for studying biomechanics of occipito-atlantoaxial complex. This study provides empirical evidence to support the use of the MS approach in tackling workplace stress. The obtained evidence is discussed in terms of the important role of striatal CRH in the choice of behavioral strategy in stress. The phylogeny suggests that horned soldiers evolved once and were lost once or twice. The p53 signature is significantly associated with lower parity and possibly higher age at first childbirth, further linking this entity to serous cancer via risk factors associated with ovulation.

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