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Quantrum (Levofloxacin)

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Quantrum belongs to the class of medicines known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Acquire, Auxxil, Bacnil, Elequine, Floracid, Iquix, Ledric, Levocin, Levocine, Levoflox, Levonidin, Levoquinox, Levores, Levosina, Levoxacin, Locin, Lovicin, Nislev, Nivoloc, Oftaquix, Quinix, Recamicina, Septibiotic, Truxa, Urilev, Voleflok, Voxin, Zenilev

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Also known as: Levofloxacin


Levofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Levofloxacin is used to treat different types of bacterial infections. Levofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague.

Fluoroquinolone antibiotics can cause serious or disabling side effects that may not be reversible. Levofloxacin should be used only for infections that cannot be treated with a safer antibiotic.


A nurse or other trained health professional will give you this medicine in a medical facility. It is given through a needle placed into one of your veins. The medicine must be injected slowly, so the needle will need to stay in place for at least 1 hour.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.

Detailed Quantrum dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Side effects

The most common side effects associated with Quantrum are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and lung transplants. Discontinue if pain or inflammation in a tendon occurs.

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose.

Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses.

Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately if signs and symptoms of hepatitis occur.

Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia may occur after the first dose. Use with caution in patients with known or suspected disorders that may predispose them to seizures or lower the seizure threshold.

Clostridium difficile-associated colitis: evaluate if diarrhea occurs.

Peripheral neuropathy: discontinue if symptoms occur in order to prevent irreversibility.

Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval.

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After therapy with the dynamic palatograph, palatolingual contact was normal in comparison with average speakers. An additional ultrastructural examination of selected nerves with characteristic values was performed. The rapidity of development of the tears in the internal elastic lamina of the muscular ilio-femoral arteries was greater than in fistulae involving the elastic common carotid artery. Thus, CD300f is an attractive target for the treatment of sepsis. What is proposed is a reintegrative approach which suggests that stable housing and employment would mitigate the disruptive and antitherapeutic effects of community notification. Combining generic and condition-specific preference-based health status measures allowed for assessment of dimensions that were particularly relevant to this patient population, while permitting comparison with outcomes from other studies, treatments, and populations via EQ-5D. Repeated urethral dilation and endoscopic optic urethrotomy may cure the short urethral strictures, but they are frustrating and time-consuming both for the patient and the physician. The evolution in the management of urinary incontinence with electronic stimulation of the pelvic floor is reviewed.

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Nitrosoureas have activity in the treatment of primary malignant brain tumors. The technique for biliary drainage in patients with Billroth II gastrectomy and normal stomach is identical. The field employs high-end analytical mass spectrometry and novel high-throughput antibody approaches to characterize as many proteins as possible. This International Society for Clinical Densitometry (ISCD) White Paper documents the role of VFA in the evaluation and treatment of women with postmenopausal osteoporosis and compares it with standard spine radiography. A consecutive series of 70 exudates from 45 patients with clinically suspected malignancy was examined by cytology, cytophotometric measurement of DNA, short-term cell culture, scanning and transmission electron microscopy. The lung irritant effects of these limonene ozone reaction products (LOP) were investigated.

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Jargon can serve useful purposes but its moral status is often dependent on the function it serves and the context in which it is used. Color masking measurement for ceramic coating of titanium used for dental implants. The Cdc25A is involved in S-phase checkpoint induced by benzo(a)pyrene. Recombinant immune interferon, (interferon-gamma, IFN-gamma) inhibits types I and III collagen synthesis by rheumatoid synovial fibroblast-like cells in culture. Age-related changes in the metabolism of cholesterol in rat liver microsomes. A mucus-secreting presacral cyst was found in a 49-year-old woman who complained of dysuria. Muscle characteristics in Thoroughbreds of different ages and sexes.

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Sleep disturbances (SD) are pronounced in Veterans with posttraumatic stress disorder (PTSD). Plain radiographs of the cervical spine revealed destruction of the left half of the 6th cervical body with an expansive soap-bubble appearance. Adrenal function was evaluated by using the high-dose corticotropin stimulation test within 24 h after brain injury and after barbiturate coma induction. Upon reduction, proteins attain different conformations with varying degrees of compactness. The objective of this study was to describe and compare histologic, histomorphometric, and regulatory characteristics in the GPs of the spine and the long bones in a porcine model. Our results revealed a significantly higher correlation between IEDs and SA with respect to SWA in all subjects, in total sleep time. Distribution of glutamic acid decarboxylase-immunoreactive structures in the barrel region of mouse somatosensory cortex. Three and six months after bilateral MICS with Acri.Lisa 366D implantation, 40 eyes of 20 patients were evaluated for surgical induced astigmatism (SIA--vector analysis), binocular UDVA, UNVA and UIVA (logMAR), spectacle independence, contrast sensitivities (CS-CSV-1000), subjective symptoms, patient satisfaction (Type Questionnaire) and complications.

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Expression of tumour-associated antigens in breast cancer primary tissue compared with serum levels. Three of the plasmids present in the organisms causing the infections were also present in the inanimate environment or in the bowel flora of patients and these also were found in different serotypes of the same species and in different genera. Radiographic demonstration of an upper-lobe cyst, particularly on the right, should suggest a tracheal bronchus. The rhabdomeres are arranged in a cross with single cell rhabdomeres lying between the arms of the cross. Despite a close structural resemblance and similar carbohydrate specificities, the lectins exhibited significant differences in their ability to induce cell proliferation of human lymphocytes.

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The development of the Separation Anxiety Symptom Inventory (SASI). We observed no hypoxia-induced regulatory effect on GAPDH expression in the three glioblastoma cell lines studied in vitro. When comparing metastatic sites, our analysis implicated a complex somatic rearrangement that was present in the metastatic tumor. Atenolol-chlorthalidone combination vs placebo: controlled clinical trial in patients with medium-mild arterial hypertension. Provocative test of coronary spasm during coronary arteriography is clinically useful.

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Multicenter Study of the Relationship between Carbapenem MIC Values and Clinical Outcome of Patients with Acinetobacter Bacteremia. Biochemical dissection of this activity indicates that it results from the physical interaction between ELF3 and AR and that this interaction inhibits the recruitment of AR to specific androgen response elements within target gene promoters. Making a full-coverage restoration on an abutment to fit an existing removable partial denture. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) available for the treatment of depression. Before cell replacement therapies can enter the clinic, it is imperative to test the therapeutic benefits in well-described animal models. Passive surveillance for congenital anomalies using birth certificates are generally considered to have biased reporting, though the sources of those biases are not well-known nor controlled for. A fatal colitis almost invariably ensued once they were discontinued.

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Analysis of the basal lamina protein, laminin, shows that when used as a culture substrate it stimulates neurite outgrowth and potentiates neuronal survival via a site associated with its heparin binding domain. Tumors were subsequently analyzed using immunofluorescence staining for hypoxia, endothelial cells, tumor perfusion, and glucose transporter expression. Improved patient and graft survival using cyclosporin A in cadaver renal transplantation. This method is amenable to rapid evaluation of anti-inflammatory agents in animal models. There were 63 women in the vegetarian (AV) group and 62 women in the nonvegetarian (NV) group.

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Newer noninvasive methods in pediatric cardiology: echocardiography, isotope angiography. A novel central partial t haplotype was generated by screening for a recombination event between overlapping distal and proximal partial haplotypes. The first crystal structure of a 54 kDa PLD has been determined to 1.9 A resolution using the multiwavelength anomalous dispersion (MAD) method on a single WO(4) ion and refined to 1.4 A resolution. Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles. Intussusception-related Hospitalizations Among Infants Before and After Private Market Licensure of Rotavirus Vaccines in Taiwan, 2001-2013. 50 years ago in the Journal of Pediatrics: the clinical behavior of the newly born: I. The five year survival rate was 100 percent for stage I, 86 percent for stage II, and 75 percent for stage III. We set out to test the hypothesis that PPARgamma ligands activate tuberous sclerosis complex-2 (TSC2), a tumor suppressor gene that inhibits mTOR signaling. Moreover, there was no sign of PspA delivery by nanogel to either the olfactory bulbs or the central nervous system after intranasal administration. Despite decades of research, the neural mechanism of central executive and working memory is still unclear.

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Acral lentiginous melanoma: histopathological prognostic features of 121 cases. Clinical manifestations of APD is caused by an unusual allergy to progesterone and has a wide range of clinical manifestations from eczema and urticaria to angioedema and erythema multiforme. Schedule-dependent synergism of edatrexate and cisplatin in combination in the A549 lung-cancer cell line as assessed by median-effect analysis. A simple method is described by which multiple cytological and cytochemical studies can be done on a clinical sample that contains relatively few cells. The serotonin(5-HT) syndrome(SS) is a condition of both the central and peripheral 5-HTergic hyperstimulation, characterized by a constellation of 5-HT-related side effects(confusion, agitation, restlessness, myoclonus, hyperreflexia, diaphoresis, shivering or tremor in the setting of the recent addition of 5-HTergic agents.

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The departure from an exponential time course of recovery during this period is more evident when the test stimulus is a disk that is defocused on the retina and sinusoidally modulated at 1 Hz than when the test stimulus is a sharp-edged disk that is either flashed for 160 msec or sinusoidally modulated at 1 Hz. Selective precipitation of proteins from guanidine hydrochloride-containing solutions with ethanol. A randomized double-blind trial with 15 postmenopausal women led to a remarkable result. Internet-delivered cognitive-behavioral therapy (ICBT) has been established as both efficacious and effective in reducing symptoms of social anxiety. Visualization of the thymus with therapeutic doses of radioiodine in patients with thyroid cancer. Unlike genetic risk factors, these can be modified, with potential for prevention, particularly in high-risk populations. Black race was significantly associated with postoperative complication and death. We detail how vaccine supply chains may affect the work and decision making of ten examples flagyl 1 gram dose of different members of the vaccine community: preclinical vaccinologists, vaccine clinical trialists, vaccine package designers, health care workers, epidemiologists and disease surveillance experts, policy makers, storage equipment manufacturers, other technology developers, information system specialists, and funders.

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The biochemical nature of these exchanges has not been determined. Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals. We propose therefore, that protonation events influence the kinetics of cytochrome b(6) oxidation at the Qi site and that these reactions are strongly influenced by the light-dependent generation of a transmembrane potential. The parasites appear to bind to the red cells in a lectin-like fashion, since three monosaccharides, namely N-acetyl-glucosamine (Glu NAc), N-acetyl-galactosamine (Gal NAc) and N-acetyl-neuraminic acid (Neu NAc), can specifically block parasite invasion in vitro. A 4.4-kilobase fragment of Campylobacter DNA encodes the genes analogous to the proA and B genes of E. The study is based on a database comprising data on all stroke patients admitted to a university hospital in Copenhagen, Denmark, over a 1-year period, 1994-95. Histopathological samples taken from the dorsal margin of the vertical canal yielded subtle and non-specific changes in the six samples submitted. Furthermore, cntn1b mutants generated by the CRISPR/Cas9 system and trans-heterozygotes of the CRISPR mutant allele and ro had abnormal swimming behavior, indicating that the cntn1b gene was responsible for the ro-mutant phenotype.

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Interfacial charge transfer dynamics in dye-sensitized NiO nanoparticles are being investigated for photocathodes in p-type dye-sensitized solar cells. However, the surface composition of high shear-induced platelet microparticles is unknown. 3) Morphine 5 and 10 mg/kg caused hyper-locomotor activity depending on the state. Therapeutic dosing of paracetamol administered for 10 days appears to elevate serum ALT in moderate drinkers, but does not produce clinically evident liver injury. A double blind crossover comparison of loperamide with diphenoxylate in the symptomatic treatment of chronic diarrhea. The results are discussed in relation to the possibility that an opioid substrate involved in habituative learning may be inhibitory on a nonopioid antinociceptive substrate. Comparison of conventional mechanical ventilation and synchronous independent lung ventilation (SILV) in the treatment of unilateral lung injury. Mechanisms of depressed natural killer cell activity in recurrent aphthous ulcers. The purpose of study was to clarify the environmental risk factor that can be easily occurred ankle sprain during walking (stance phase) and one leg standing at various ramp environment. The standard passive avoidance procedure revealed an age-related memory impairment in old rats fed a standard diet (ST), whereas old rats fed a hypocaloric diet (HY) behaved similarly to young animals.

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Though shapes of dim light melatonin rhythm did not differ between the groups, phase angle between melatonin and sleep propensity rhythms was wider in DSPS patients than in controls. Two years of growth hormone treatment in adults with Prader-Willi syndrome do not improve the low BMD. A variety of interrelationships of diseases and genetic dispositions concerning the locomotive and cardiovascular system interferes with the required forensic evidence between individual sickness and housing and/or neglected care. Separation was carried out on an octadecyl silica stationary phase and a disodium phosphate solution (pH 3.7) containing citric acid, octane sulphonic acid and acetonitrile served as mobile phase. We report the case of a 77-year-old man who was admitted to the intensive care unit with a serum digoxin level of 45.9 ng/mL. Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models. The complexity of this post-traumatic squeal involves a cellular component, comprising the activation of resident glial cells, microglia, and astrocytes, and the infiltration of blood leukocytes. Bristol-Myers Squibb, Clinical Pharmacology Unit, Princeton, New Jersey, USA.

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Impact of amino acid sequence variation on the antigenic properties of the surface hepatitis B virus antigen HBsAg was studied. This study will reveal barriers and facilitators for implementation of the ultra short stay programme. Carrier determined tolerance with various subclasses of murine myeloma IgG. Evaluation of the endocrine disrupting capacity of pesticides will be a domain of applicability of these future reference tests. The deletion was at 5p15 in four patients, whereas the fifth had a larger, more proximal deletion at 5p14. The current body of literature is germinal, but warrants the further investigation of planned clinical trials. The hexapeptide, Ac-RCGVPD, and the pentapeptide, Ac-RCGVP tetracycline name brand had IC50 values of approx. Standard metabolites were examined: n-acetylaspartate (NAA), myo-inositol, choline, creatine and glutamate-glutamine. However, most existing methods are proposed based on the single view data.

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Improved methods for embedding with water-miscible methacrylates. Using spleen cells from a mouse immunized with blood group A secretor saliva, we obtained 3 monoclonal anti-A antibodies (3H9, 5C6, 4D8) and 1 monoclonal anti-A,B antibody (2D10). It is recommended that Norwegian laboratories be prepared to isolate vibrios also in domestically infected cases when watery diarrhoea is present. Although ERs have been reported to be expressed in the bovine corpus luteum (CL), the mechanisms that control ER expression in the bovine CL are not fully understood. Vaccination and clinical histories were obtained from general practitioners. The registry is intended to be a source of clinical information for the members, as well as a tool for the conduct of retrospective and prospective clinical and epidemiologic studies. To develop and test a model to procure premix through a transparent and efficient process in which an adequate level of quality is guaranteed and a financial mechanism is in place to support countries or specific target groups when there are insufficient resources to cover the cost of premix.

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Because of a pathologic cardiotocogram it was necessary to make a primary caesarean section one day later. Effect of water, saliva and blood contamination on bonding of metal brackets with a 4-META/MMA/TBB resin to etched enamel. The use of dietary loading of 133Cs as a potassium substitute in NMR studies biaxin of tissues. Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR. Two different forms fo chronic atrophic gastritis are to be distinguish concerning localization and etiology. Chemical nature of agrocin 84 and its effect on a virulent strain of Agrobacterium tumefaciens. Vertebrae predicted to be at risk for vertebral arterial injury were imaged by computed tomography. The postexercise session of ERPs showed a significant P300 amplitude increase and a significant P300 latency decrease in all subjects. Chelation therapy in the JCR:LA-cp rat: experimental assessment of a putative antiatherosclerotic treatment.

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