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Prometrium (Progesterone)

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Prometrium is in a class of medications called progestins (female hormones). It works as part of hormone replacement therapy by decreasing the amount of estrogen in the uterus. It works to bring on menstruation by replacing the natural progesterone.

Other names for this medication:
Algest, Belgest, Conest, Corion, Crinone, Cygest, Durbagest, Egeria, Endometrin, Evagest, Forgest, Gemgest, Gestorin, Hilgestrone, Hormorin, Isogest, Lutacare, Macgest, Minagest, Miprogen, Namgem, Natron, Naturogest, Naturone, Npton, Orgasest, Ornapro, Pgfast, Pregcitil, Preglon, Pregzed, Progesterone, Progez, Progminat, Pyrtex, Rigest, Rivgest, Strone, Sugest, Theragest, Truegest, Vageston, Zesty, Zygogest

Similar Products:
Imitrex, Parlodel, Ultram, Altace, Zebeta, Uflox, Inmecin, Mandol, Flodart, Deptune, Damol, Robamox, Etobrom, Fenoglide,

Also known as: Progesterone


Progesterone is used to help prevent changes in the uterus (womb) in women who are taking conjugated estrogens after menopause. It is also used to properly regulate the menstrual cycle and treat unusual stopping of menstrual periods (amenorrhea) in women who are still menstruating.

This medicine is available only with your doctor's prescription.


Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Take the Prometrium capsule with a full glass of water. It is best to take the medicine at night because this medicine can make you dizzy or drowsy.

Apply Prometrium cream to the skin as directed by your doctor.

Prometrium is sometimes used for only a short time, such as 10 to 12 days during each menstrual cycle. Follow your doctor's dosing instructions very carefully.

Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Prometrium.

If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Prometrium.

Store at room temperature away from moisture, heat, and light.

Detailed Prometrium dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Prometrium dosage information

Side effects

The most common side effects associated with Prometrium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Although appropriate studies on the relationship of age to the effects of progesterone have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving progesterone.

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