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Neurontin

Neurontin is used to treat epilepsy. It's also taken for nerve pain. Nerve pain can be caused by different illnesses, including diabetes and shingles, or it can happen after an injury. Occasionally, Neurontin is used to treat migraine headaches.

Other names for this medication:
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Also known as: Gabapentin

Description

Neurontin (gabapentin) is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Neurontin is used in adults to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster).

Neurontin is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

Dosage

Usual Adult Dose for Epilepsy:

Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three Maintenance dose: 300 to 600 mg orally 3 times a day Maximum dose: 3600 mg orally daily (in 3 divided doses) -Maximum time between doses in the 3 times a day schedule should not exceed 12 hours Comment: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization

Usual Adult Dose for Postherpetic Neuralgia:

-Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three -Titrate up as needed for pain relief -Maximum dose: 1800 mg per day (600 mg orally 3 times a day) COMMENT: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded.

Usual Pediatric Dose for Epilepsy:

Less than 3 years: Not recommended Greater than or equal to 3 and less than 12 years: Starting Dose: Ranges from 10 to 15 mg/kg/day in 3 divided doses Effective Dose: Reached by upward titration over a period of approximately 3 days; the effective dose in patients 5 years of age and older is 25 to 35 mg/kg/day in divided doses (3 times a day). The effective dose in pediatric patients ages 3 and 4 years is 40 mg/kg/day and given in divided doses (3 times a day). Gabapentin may be administered as capsule, or tablet, or using combinations of these formulations. Dosages up to 50 mg/kg/day have been well tolerated in a long term clinical study. The maximum time interval between doses should not exceed 12 hours. Greater than 12 years: -Initial dose: 300 mg orally on day one, 300 mg orally 2 times a day on day two, then 300 mg orally 3 times a day on day three -Maintenance dose: 900 to 1800 mg orally in 3 divided doses; the dose may be increased up to 1800 mg/day. Dosages up to 2400 mg/day have been well tolerated in long term clinical studies. Doses of 3600 mg/day have also been administered to a small number of patients for a relatively short duration, and have been well tolerated. The maximum time between doses in the three times a day schedule should not exceed 12 hours. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization in patients 3 years of age and older

Detailed Neurontin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Neurontin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Neurontin if you are allergic to Generic Neurontin components. Do not take Generic Neurontin if you are pregnant, planning to become pregnant. Avoid breast-feeding. Be careful with Generic Neurontin if you are taking morphine (such as MSIR, Avinza, Kadian), hydrocodone (in Vicodin, in Hydrocet), naproxen (such as Anaprox, Aleve, Naprosyn). Generic Neurontin can be used together with other seizures medicines. Be very careful with Generic Neurontin if you suffer from or have a history of heart, kidney or liver disease. Be careful with Generic Neurontin if you are going to have a surgery. Children should be very careful with Generic Neurontin because it can cause changes in behavior. If you experience drowsiness and dizziness while taking Generic Neurontin you should avoid any activities such as driving or operating machinery. Avoid alcohol. It can be dangerous to stop Generic Neurontin taking suddenly.

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The p38 inhibitor SB202190 blocked LPS-stimulated TNF production. HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis. Arthritis as a potential barrier to physical activity among adults with diabetes--United States, 2005 and 2007. Electromagnetic interference of communication devices on ECG machines. In order to estimate the relative enhancement in bioavailability one optimized formulation was evaluated in rabbits. Here, we show that recombinant Drosophila elp1 (D-elp1) produced in Sf9 cells or Escherichia coli, corresponding to the largest of the three subunits in the RNA polymerase II core elongator complex, has RNA-dependent RNA polymerase (RdRP) activity. 3D virtual-reality reconstruction demonstrated the position of the tumor in the segment and regarding the vessels. In a proteomic analysis of rpoS-deficient Vibrio vulnificus versus the wild type, one of the down-regulated proteins in the rpoS mutant strain was identified as a Fur protein, a ferric uptake regulator.

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We describe a 30 year old man who developed chronic adipsic hypernatraemia and hypothermia following a subarachnoid haemorrhage from an anterior communicating artery aneurysm. Studies on the preventive and therapeutic effects of ursolic acid (UA) on acute hepatic injury in rats. Patients with isolated malignant and benign diseases of the left lateral segment of the liver are candidates for totally laparoscopic resection, if evaluation demonstrates a normal liver character and hepatic parenchymal thickness less than 3 cm overlying the ligamentum venosum groove. Is prehypertension really different from normotension and hypertension?. Interviews and surveys were conducted to obtain an in-depth picture of OPs experiences. It is less certain as to whether they have superior local processing. To evaluate genotyping as a diagnostic complement to neonatal screening for congenital adrenal hyperplasia, 91 children who had been diagnosed with this condition between 1986 and 1997 were analyzed for mutations in the steroid 21-hydroxylase gene. Report of one semester of activity of the blood bank of the Institute of Surgical cleocin and breastfeeding Pathology of Sassari. In this article, we develop a bivariate ordered Probit model to analyze the decision to fasten the safety belt in a car and the resulting severity of accidents if it happens. Timely PA did not markedly contribute to overall patient or facility SSI rates.

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