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Medrol (Methylprednisolone)

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Medrol tablets belong to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Oral steroids are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases, autoimmune diseases, joint and muscle diseases, and allergies. They are also used to treat some cancers.

Other names for this medication:
Acnex, Avpred, Cartipred, Hysone, Meprolone, Methylprednisolone, Predon, Prelonb, Sterid, Zempred, Zencort

Similar Products:
Ambien, Glucotrol, Altace, Nuvigil, Epivir, Tetragen, Cobese, Tebsil, Renea, Eurythmic, Ciclinil, Vandep, Docenala, Rizkold,

Also known as: Methylprednisolone


Depo-Medrol is a steroid that prevents the release of substances in the body that cause inflammation.

Depo-Medrol is used to treat many different inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, allergic disorders, gland (endocrine) disorders, and conditions that affect the skin, eyes, lungs, stomach, nervous system, or blood cells.


This section provides information on the proper use of a number of products that contain methylprednisolone. It may not be specific to Depo-Medrol. Please read with care.

A nurse or other trained health professional will give you this medicine. It may be given through a needle placed into one of your veins, as a shot into a muscle or joint, or as a shot into a lesion on your skin.

Your doctor may give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Depo-Medrol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of methylprednisolone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Medrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not be treated with Depo-Medrol if you are allergic to it. You may not be able to receive a this medicine if you have a fungal infection.

Depo-Medrol can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Tell your doctor if you have ever had:

heart disease, high blood pressure; a thyroid disorder; diabetes; glaucoma or cataracts; kidney disease; cirrhosis or other liver disease; seizures, epilepsy or recent head injury; past or present tuberculosis; herpes infection of the eyes; a condition called scleroderma; stomach ulcers, ulcerative colitis, diverticulitis, or recent intestinal surgery; a parasite infection that causes diarrhea (such as threadworms); mental illness or psychosis; osteoporosis or low bone mineral density (steroid medication can increase your risk of bone loss); a muscle disorder such as myasthenia gravis; or an electrolyte imbalance (such as low levels of potassium in your blood).

It is not known whether Depo-Medrol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using Depo-Medrol.

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Induction of experimental myasthenia gravis in rhesus monkeys: a model for the study of the human disease. Three clinicians independently read and rated the records of 40 child and adolescent patients. Genetic algorithm as a variable selection procedure for the simulation of 13C nuclear magnetic resonance spectra of flavonoid derivatives using multiple linear regression. In some individuals, high levels of MIP-1alpha, IL-10, and sICAM-1 could be found. It is essential that scientists and funding institutions avoid misrepresentation and accurately communicate the scope of their work. 25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children. Dosage was 0.01, 0.05 or 0.25 mg/kg, five times a week, or 0.05, 0.25 or 1.25 mg/kg once a week. The sites of the respiratory chain that were sensitive to peroxidative damage were ubiquinone-cytochrome c oxidoreductase and NADH-ubiquinone oxidoreductase. Environmental considerations are gradually becoming more important than mere technological improvements, and educational inputs try to create safer surroundings by recognizing human factors such as efficient communication, awareness, error culture, crew resources utilization, and preparedness for more effective crisis management. The present meta-analysis demonstrated that preoperative administration of EPO in pediatric craniosynostosis surgery decreased the proportion of patients requiring ABT.

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Various extraction procedures and proteinase treatments yielded strong evidence that it is an integral part of the membrane without a stalked hydrophilic head exposed to the outer surface. Two authors abstracted data independently and settled any differences by discussion. NalphaA1-N-epsilon B-29-crosslinked diaminosuberoylinsulin, a potential intermediate for the chemical synthesis of insulin. No intracranial injuries were discovered in any of the low-risk patients. Periodate-treated MnPH4 exhibited even lower thermal stability than O-glycosidase treated MnPH4. This article provides an overview of the pathology of the ocular motor nerves. Our results provide a basis for future investigations into multi-electrode-based control interventions of alternans in cardiac tissue. In addition, recent work has revealed another, DNA-damage-independent function of Chk2 during mitosis that is required for proper mitotic spindle assembly and maintenance of chromosomal stability. The patient was found to have an asymmetry on pure-tone audiometry and an auditory processing deficit, suggesting central pathology. During embryonic development, alpha-taxilin was prominently expressed in nestin-positive neural stem cells in vivo and in vitro.

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Women and men were equally likely to experience less severe acts of physical aggression that were not embedded in a pattern of control. We have therefore established its limits, and we have submitted a study including new parameters in order to refine the characterization of roles. Second, when the resulting PA-Ch6S(hexa-)-Ch4S(di-)octasaccharide and chondroitin (Ch) were used as an acceptor and as a donor containing GalNAc, respectively, a new decasaccharide having a hybrid structure composed of disaccharide units derived from Ch6S, Ch4S and Ch was reconstructed. On-line liquid chromatography/electrospray ionization high-resolution mass spectrometry (LC/ESI-HRMS) using an LTQ-Orbitrap mass spectrometer was employed to investigate the metabolite profiles of a model siRNA duplex designated HBV263. Six patients died of tumor recurrence in 6, 11, 12, 13, 15, 19 mo after operation, respectively. The first experiment utilised UV powder, an established proxy for geoforensic trace particulates and the second experiment utilised daffodil pollen transferred onto garments under conditions that mimicked forensic reality. We have used bioinformatic approaches to analyze codon usage bias of human Y-linked genes. Polydactyly, athetoid cerebral palsy, severe mental subnormality and malnutrition. Varying parameters in each patient (e.g., elimination kinetics of PPC, activity of the cumarin-dependent blood-clotting factors, endogenous phytomenadion stores), render it impossible to use a different means of monitoring than that of PT determination.

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Attenuation of AH26-induced apoptosis by inhibition of SAPK/JNK pathway in MC-3T3 E1 cells. Fall risk-assessment tools compared with clinical judgment: an evaluation in a rehabilitation ward. DNA topoisomerase I activity in regenerating liver of hypothyroid rats. In addition, the combination of targeted drugs with common chemotherapeutic agents might be able to make resistant cells again sensitive towards a chemotherapeutic agent. The role of genetic association studies in identifying new drug targets. These findings demonstrate that the fetus and its immediate surroundings are permeated with interferon. This paper presents a novel conformal thermal monitoring sheet (TMS) sensor array with differential thermal sensitivity for measuring temperature distributions over large surface areas. Long-term consequences of developmental vascular defects on retinal vessel homeostasis and function in a mouse model of Norrie disease. To investigate serum levels of soluble VE (sVE)-cadherin in patients with CSU. The only known binary phosphorus(V) oxides have tetrahedral P coordination.

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To assess the relative incidence of peptic ulcer bleeding and perforation (PUBP) in users of selective cyclooxygenase-2 (COX-2) inhibitors and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs). A high-throughput assay for quantitative measurement of PCR errors. Kinetics of enzymatic synthesis of peptides in aqueous/organic biphasic systems. Genotyping of polymorphisms for CYP17A1, CYP19A1, VDR, and the CAG repeat from AR was carried out using pyrosequencing. Determination of predictive factors for the failure of osteosynthesis with the loss of fixation or migration of screws in humeral head fractures.

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The model time horizon and patient body weight were important factors affecting results. The observations of hyper-oxygenation as well as hypo-oxygenation in the present investigation extend past studies and suggest a complex phenomenon of activation that may be the result of a vascular steal mechanism, attenuated activation baselines, or active cortical deactivation. A control group of patients matched for sex, age, type of graft, etiology of kidney disease, and BMI, was established for comparison. Staphylococci cocultured with cartilage increased release of proteoglycan 3-4-fold within 48 hours. Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block.

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Prenatal inflammatory effects on nigrostriatal development in organotypic cultures. The following comparisons were made: angle of gait in children unshod versus children shod without treatment, angle of gait in children shod without treatment versus children shod plus orthoses, and angle of gait in children unshod versus children shod plus orthoses. The reasons for the transition from asymptomatic dysfunction to heart failure need better definition, including noninvasive measurements that can detect the transition. Additionally, S100A11 down-regulated HaCaT cells showed a restricted proliferation capacity and an increase of the apoptotic cell fraction. Although there are currently no effective medications for CMT, multiple clinical trials are ongoing or being planned. Management of PSC patients without cirrhosis remains controversial. Our sample included 367 youth from 13 urban and suburban middle schools. This mutant was capable of growing slowly and maturing under low-light conditions, but, rapidly died under natural light conditions. Study subjects were divided into an environmental exposure (EE) group or a natural exposure (NE) group. Weakening of the triceps surae by Botulinum toxin allowed patients to perform the required exercises and to tolerate casting at night.

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Epilepsy and suicide: pathogenesis, risk factors, and prevention. Exploration into electrical stimulation of the retina has thus far focussed primarily upon the development of prostheses targeted at one of two sites what is the generic of lipitor called of intervention - the epi- and sub-retinal surfaces. Agatston scores were obtained at 3.0-mm slices for CT calcium score and CTA. Public Health Service have recommended the use of counseling and pharmacologic therapies for all patients interested in quitting smoking. Midkine promoter-based conditionally replicative adenovirus might be a promising new gene therapy for pancreatic cancer.

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Exposure and sensitization to pet allergens are associated with allergic asthma in children. Rats subjected to a 4 h heat stress at 38 degrees C in a biological oxygen demand (BOD) incubator exhibited profound increases in BBB and BCSFB permeability to Evans blue and radioiodine tracers compared to controls. Following sections will review hepatic signaling molecules involved in the protective actions of adiponectin against alcoholic fatty liver and summarize the current knowledge of regulatory mechanisms of adiponectin expression and secretion in response to chronic ethanol exposure. Second, during the postinstruction epoch, GO and NOGO action-related activities were highly selective to reward size. To evaluate enteric-coated mycophenolate sodium (EC-MPS) as a corticosteroid-sparing agent in the treatment of autoimmune scleritis. Understanding such specifics will improve patient information leading patients to a more conscious motivation in deciding whether to participate in a clinical trial. After excluding mutations in ADAR and linkage to the candidate regions on chromosomes 1 and 6, we performed an single nucleotide polymorphism-based genome-wide scan for linkage with other loci. Selective alpha 1 antagonists decrease blood pressure by reducing elevated peripheral resistance and preserving normal cardiac reflexes.

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