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Lodine (Etodolac)

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Lodine treats mild to moderate pain associated with arthritis and other painful conditions. Lodine helps to relieve swelling, inflammation and stiffness. Lodine comes in tablet and capsule form. It is taken 2 or 3 times daily for arthritis and up to 4 times daily for other causes of pain.

Other names for this medication:
Etios, Etobest, Etodolac, Etofree, Etogesic, Etomax, Etoron, Etosafe, Etova, Etura, Freeup, Penalgon, Proxym, Setolac, Toldin

Similar Products:
Pyridium, Desyrel, Aristocort, Duphaston, Coumadin, Amethopterin, Singulair, Risperdal, Seroquel, Rosatan, Lactone, Alpradol, Glipiriv, Pantest, Wylor, Sysron, Lopram, Asicom,

Also known as: Etodolac


Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis and rheumatoid arthritis), including inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain etodolac. It may not be specific to Lodine XL. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute pain: For oral dosage form (capsules or tablets): Adults—200 to 400 milligrams (mg) every 6 to 8 hours. However, the dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

For osteoarthritis and rheumatoid arthritis: For oral dosage form (capsules or tablets): Adults—300 milligrams (mg) 2 to 3 times a day, or 400 or 500 mg 2 times a day. Your doctor may lower your dose to 600 mg once a day. The dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—400 to 1000 milligrams (mg) once a day. Children 6 to 16 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, stomach pain, or stomach bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Lodine XL dosage information

Side effects

The most common side effects associated with Lodine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Valproate is available in various formulations that differ primarily in their absorption profiles. Bayesian structure learning (BSL) techniques and its extensions have been used successfully for modelling FRs from expression profiles. The MM energy minimisations are much more successful than those using the AFEM, and we analyse the failure of the latter approach both qualitatively and quantitatively. Diagnostic accuracy and potential limitations of transvaginal sonography for bladder endometriosis. We present two cases in which abscessograms revealed unsuspected fistulous communication to an incompletely or intermittently obstructed biliary tree with retained stones. Molecular approaches are best suited for epidemiologic purposes and for selected clinical conditions such as early identification of treatable agents in at-risk patients, rather than for cases requiring only oral rehydration. At conscription, males born preterm had lower results at tests of intellectual performance compared to those born at term.

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Hepatic miRNA expression reprogrammed by Plasmodium chabaudi malaria. Astrocyte-derived CCL2 participates in surgery-induced cognitive dysfunction and neuroinflammation via evoking microglia activation. The secondary outcome measures showed a difference on supported housing and use of bed-days at the five-year follow-up in favour of OPUS treatment. Transparency and openness from all involved is the cornerstone of this and our processes are intended to prevent, as far as is possible, financial, personal, intellectual, professional, political, religious, racial, gender-related or other conflicts of interest affecting our peer-review. This observation stresses the importance of recognizing both behavioral and morphological components of the mate-recognition system. There is evidence that initiating toilet training after 24 months is associated with problems attaining and maintaining bladder control. This review describes the current data with this technology and also the potential for the future role of the technology, including potential ways to yet further improve the short- and longer-term results. Based on these findings, a framework of key outcomes to assist multidisciplinary teams in genetic counselling of probands receiving an HCM gene result was developed.

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