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Levothroid (Levothyroxine)
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Levothroid

Levothroid is a synthetically prepared thyroid hormone that can improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin, and feeling cold. There are several brand and generic Levothroid choices available, though they may not be interchangeable.

Other names for this medication:
Eltroxin, Levothyroxine, Levoxyl, Roxin, Synox, Synthroid, Thyronorm, Thyrosec, Thyrowin, Thyrox, Unithroid

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Reminyl, Trandate, Prevacid, Inderal, Rogaine, Avodart, Dulcolax, Mircette, Maxalt, Apirol, Avizole, Cenforce, Sulfamethoxazol, Escita, Wenkill, Optiviral, Flagolin,

Also known as: Levothyroxine

Description

Levothyroxine injection is used to treat myxedema coma (severe hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. The powder form of levothyroxine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed.

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Solution

Dosage

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection form (powder for solution):
    • For the treatment of hypothyroidism:
      • Adults—50 to 100 micrograms (mcg) injected into a muscle or vein once a day. People with very serious conditions caused by too little thyroid hormone may need higher doses.
      • Children—Dose is based on body weight and must be determined by your doctor.
  • For injection form (powder for solution):
    • For myxedema coma:
      • Adults—The loading dose is usually 300 to 500 micrograms (mcg) injected into a vein once a day. The maintenance dose is usually 50 to 100 mcg injected into a vein once a day. Your doctor may adjust your dose as needed and tolerated.
      • Children—Use and dose must be determined by your doctor.

Overdose

If you take too much Levothroid, call your local Poison Control Center or seek emergency medical attention right away.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.

Side effects

The most common side effects associated with Levothroid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you will be taking this medicine for a long time, it is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood tests will be needed to check for unwanted effects.

Levothyroxine should not be used for the treatment of obesity or for the purpose of losing weight. This medicine is not effective for weight reduction. If taken in large amounts, levothyroxine may cause serious unwanted effects.

Hypothyroidism can sometimes cause infertility in men and women. Levothyroxine should not be used for the treatment of infertility unless it is caused by hypothyroidism.

For patients with diabetes: It is very important that you keep track of your blood or urine sugar levels as instructed by your doctor. Check with your doctor right away if you notice any changes in your sugar levels.

If you think you have become pregnant while using this medicine, tell your doctor right away. You may need a larger dose of levothyroxine while you are pregnant.

Women who are post-menopausal or who use this medicine for a long time may have some bone loss, which could lead to osteoporosis. Talk with your doctor if you have questions or concerns about this.

Call your doctor right away if you or your child start to have rapid or irregular heartbeats, chest pain, leg cramps, headaches, nervousness, irritability, sleeplessness, tremors, a change in appetite, weight gain or loss, vomiting, diarrhea, excessive sweating, heat intolerance, a fever, changes in menstrual periods, hives, or a skin rash. These could be symptoms of too much medicine in your body.

Do not suddenly stop taking this medicine without first checking with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping completely.

Make sure any doctor or dentist who treats you knows that you or your child are using this medicine. You or your child may need to stop using this medicine several days before having surgery or medical tests.

A temporary loss of hair may occur during the first few months of levothyroxine therapy. Ask your doctor about this if you have any concerns.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

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Blood loss during liver resection is one of the most important factors affecting the peri-operative outcomes of patients undergoing liver resection. Effective discipline of incompetent physicians: number one problem and need of state licensing boards. Metal and oxalate contamination in a suburban watershed in the greater Toronto area: the benefits of combining acid leach and selective extraction procedures. A total of 238 premedical students provided demographic information regarding themselves and their parents. (1980) Virology 105, 205-222) was located within the predicted protein sequence. This first report of a stone-tool-use tradition in Japanese macaques is of direct relevance to the question of the evolution of stone technology in hominids. These data are in contrast to the changes found in liver fractions where exposure to Fe greatly enhanced hepatic pro-oxidant events as judged by changes in all three of the test indices used. Sources for this paper include published literature and research on issues related to parenting with mental illnesses. Medical safety in boxing: administrative, ethical, legislative, and legal considerations. GALT mutations and whole milk consumption increased the risk of cataract formation in high LPH genotype group, but not in lactose intolerant subjects.

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For health-related quality of life (HRQOL), we used SF-8 with a physical component summary (PCS8) and a mental component summary (MCS8). Traumatic brain injury (TBI), one of the most frequent causes of neurologic and neurobehavioral morbidity in the pediatric population, can result in lifelong challenges not only for patients, but also for their families. Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia. 68Ga-PSMA PET/MR-Positive Peritoneal Metastasis in the Falciform Ligament in Recurrent Prostate Cancer. The pharmacological treatment of anxiety can interact with the bipolar disorder and has not been proven effective. The simple HSCCC method was established according to the selected solvent system for separation and purification of rupestonic acid. Overcompensation in prr7 prr9 mutants does not rely on FLOWERING LOCUS C, a previously identified gene required for temperature compensation. The CCM signals were delivered in random order of ON for 3 months and OFF for 3 months. The Smo inhibitor PF-5274857 has both preventive effect and therapeutic potential against CS-induced EMT.

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Heart development is complex and requires the sequential and timely interplay of regulatory master proteins, notably several transcription factors. Prognostic value of the B-type natriuretic peptide (BNP) in a cardiogeriatric department. Trait vulnerability to sleep loss is observed in the laboratory and in the work environment, even in occupational settings where (self-)selection pressures are high. HOX11 is a homeodomain-containing oncogenic transcription factor that immortalizes hematopoietic precursor cells. The present study aimed to examine the effects of LFG-500 on human ovarian cancer SKOV3 cells, as well as to identify its underlying mechanisms. Two cases of SCV stenosis after cannulation with hemodialysis catheters (HCs) are reported. T4 patients with a negative SLN have an excellent prognosis in the absence of ulceration and should not be considered candidates for adjuvant high-dose interferon. Application to the estimation of risks associated with driving under the influence of cannabis or alcohol.

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Enteroaggregative Escherichia coli Adherence Fimbriae Drive Inflammatory Cell Recruitment via Interactions with Epithelial MUC1. Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells. For the control condition, pilots drank no alcohol within 48 hours before the simulated flight. The associated ECAs are another factor that causes increased mortality both in antenatal and neonatal life, again warranting an early fetal echo. Maintenance of eNOS activity may be associated with the protective effect of PARP-1 gene deletion against dyslipidemia-induced endothelial dysfunction. Malformations and mortality in individual fish were also scored.

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