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Duphaston (Dydrogesterone)

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Duphaston is a synthetic progestogen and has a similar action to the female hormone, progesterone. It is used to treat menstrual disorders in women caused due to a lack of hormones. It is also used to reduce the risk of miscarriages or abortions. This medicine is not recommended for use in patients below 18 years of age.

Other names for this medication:
Climaston, Dabroston, Didrogesterona, Didrogesterone, Dirogest, Dufaston, Dydrogesteron, Dydrogesterone, Dydrogesteronum, Femaston, Femoston, Femphascyl, Gestatron, Isopregnenone

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Also known as: Dydrogesterone


Generic Duphaston is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus. At therapeutic levels, Generic Duphaston has no contraceptive effect as it does not inhibit or interfere with ovulation or the corpus luteum. Furthermore, Generic Duphaston is non-androgenic, non-estrogenic, non-corticoid, non-anabolic and is not excreted as pregnanediol. Generic name of Generic Duphaston is Dydrogesterone. Duphaston is also known as Dydrogesterone. Brand name of Generic Duphaston is Duphaston.


The dosage schemes below are meant as general recommendations. For optimal therapeutic effect, the dosages are to be adapted to the nature and severity of the disorder. In irregular cycles due to endogenous progesterone deficiency Generic Duphaston 5 to 10 mg is recommended especially in irregular cycles due to shortened luteal phase (ie pre-menopause). Treatment should be repeated for several cycles. In secondary amenorrhoea Administration of Generic Duphaston in combination with an estrogen is usually recommended as in these conditions endogenous progesterone deficiency is nearly always accompanied by estrogen deficiency. 0,05 mg ethinylestradiol is administered each day from the 1st to the 25th day of the cycle, and 5 mg Generic Duphaston is added twice daily from the 11th to the 25th day. Five days after the subsequent withdrawal bleeding, the same is repeated to imitate a natural cycle. In dysfunctional uterine bleeding The symptomatic treatment is aimed at stopping the bleeding and including a subsequent withdrawal bleeding. To stop bleeding: Generic Duphaston 10 mg together with 0,10 mg ethinylestradiol twice daily for 5 to 7 days. To prevent heavy bleedings: Generic Duphaston 5 mg twice daily from day 11 to day 25 of the cycle, if necessary, combined with an estrogen during the first half of the cycle. In post-menopausal complaints If for the symptomatic treatment of post-menopausal complaints estrogens are used (hormone replacement therapy A?A?A? HRT), Generic Duphaston 10 mg is used to counteract the effects of unopposed estrogens on the endometrium. A subsequent withdrawal bleeding is induced. On continuous estrogen therapy: Generic Duphaston 10 mg twice daily during the first 12 to 14 days of each calendar month. On cyclic estrogen therapy: Generic Duphaston 10 mg twice daily during the last 12 to 14 days of the treatment. If you want to achieve most effective results do not stop taking Generic Duphaston suddenly.


If you overdose Generic Duphaston and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Duphaston overdosage: diarrhea, stomach pain, hot and dry skin, confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, and muscle weakness or limp feeling.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Duphaston if you are allergic to Generic Duphaston components. It is unknown how Generic Duphaston affects pregnant women or nursing mother. Do not take Generic Duphaston if you have undiagnosed vaginal bleeding or a history of thromboembolic disorders. Be careful with Generic Duphaston if you have cardiovascular, renal or hepatic impairment, diabetes mellitus, asthma, epilepsy and migraine, history of mental depression. Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Do not stop taking Generic Duphaston suddenly.

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The isometric contractions of isolated guinea-pig ileum, guinea-pig gallbladder, guinea-pig and rat atrial strips in in vitro organ bath were recorded on a polygraph and the effects of carbachol, oxotremorine, McN-A-343, and clozapine have been investigated. Magnetic resonance (MR) diffusion-weighted imaging (DWI), dynamic susceptibility contrast-enhanced perfusion imaging (DSC), and MR spectroscopy (MRS) techniques provide specific physiologic information that may distinguish malignant glioma progression from post-radiation change, yet no single technique is completely reliable. Our analyses by quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR), microarray data mining, and histochemical detection of GUS activity driven by the UGT71C1 promoter region, revealed the tissue-specific expression patterns of UGT71C1 with highest expression in roots. Dry season distribution of land crabs, Gecarcinus quadratus (Crustacea: Gecarcinidae), in Corcovado National Park, Costa Rica. Voltage-gated sodium-channels could be identified in laminin-predifferentiated USSCs.

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ISPsa2, the first mobile genetic element to be described and characterized in the bacterial facultative intracellular pathogen Piscirickettsia salmonis. We quantified the spatial efficacy of alternans control across 2.5 cm of tissue, focusing primarily on differences in spatial control within several sub-regions of tissue. Exogenous peroxynitrite stimulated cytotrophoblast apoptosis but only at high levels (1000 microM). The sensitivity of sensors based on SnO2 monolayer hollow spheres is up to 51 at 100 ppm ethanol, which is much higher than that of two other samples. Experimental results indicate that a Fe/Al electrode pair is the most efficient choice of the four electrode pair combinations in terms of energy consumption. The polluting landfills need to be prioritized to undertake necessary control and remedial measures. Essentials Prophylaxis is the standard of care for congenital factor XIII-A (FXIII-A) deficiency. Baseline receptor levels and stress-induced activation of mu-opioid system neurotransmission compared between subjects scoring above and below the population median on the NEO Personality Inventory, Revised, impulsiveness subscale and the orthogonal dimension (deliberation) expected to interact with it. I-131 MIBG imaging revealed both a primary abdominal tumor and a distant metastatic orbital tumor. Postoperatively, although abdominal computed tomography scan showed stenosis of portal vein anastomosis site, liver function tests improved, and Doppler sonogram revealed no flow disturbance.

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To gain insight into nonclinical factors potentially influencing tracheostomy practice and determine whether a specialized consultation form impacts tracheostomy utilization. Type 2 diabetes mellitus (T2DM) is a common complex phenotype that by the year 2010 is predicted to affect 221 million people globally. Cytokinesis in plants is achieved by the formation of the cell plate. These results are similar to previous results obtained with tripelennamine and pentazocine suggesting that nalbuphine may have abuse potential if combined with tripelennamine. Allergic diseases, particularly in childhood, have become one of the epidemics of the 21st century. This paper focuses on electroencephalography (EEG) neurofeedback in which the neural measures of interest are the brain oscillations. Disruption of membrane barrier integrity led to increased migration of neutrophils. These drugs show great promise in vitro against a number of cancer cell lines and due to their polymeric nature will most likely be less toxic than currently used metal-containing drugs such as cisplatin.

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Estrogen treatment up-regulates female genes but does prilosec 10 mg not suppress all early testicular markers during rainbow trout male-to-female gonadal transdifferentiation. This is the first reported case of exercise-induced AKI associated with RPLS. CTS induced activation of p38 MAPK, and CTS induction of RUNX-2, MMP-13 and ADAMTS-5 mRNA was down-regulated by the selective p38 MAPK inhibitor SB203580 but not by the p44/42 MAPK inhibitor U0126, or the JNK MAPK inhibitor JNK inhibitor II. To investigate the effect of MR in patients with AF and LAT on new CVA and mortality. They might be interpreted as a consequence of a zoonosis, which has been spreading since 1990 in ruminants of central France. During one of these episodes, we documented a stepwise transition of 2:1 atrioventricular block to 1:1 conduction, following two single ventricular premature beats.

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Two-dimensional views of replicas revealed that AMPARs form microclusters in both synapses to a similar extent, resulting in larger AMPAR-lacking areas in the CG synapses. In the current study we show that the basal lipolytic rate is higher in adipocytes from each deposit of obese rats (when results are corrected for cell surface area). We show that both Lhx9 and Lhx2 bind the LIM domain binding protein Ldb1/Nli1/Clim2. Molecular cloning and characterization of a cytosolic manganese superoxide dismutase (cytMnSOD) and mitochondrial manganese superoxide dismutase (mtMnSOD) from the kuruma shrimp Marsupenaeus japonicus. Systemic treatment with trans-chalcone inhibited skin inflammation by reducing skin edema and neutrophil recruitment, and also inhibited matrix metalloproteinase-9 activity. To evaluate the localization of phospholipase C zeta (PLC zeta) in non-capacitated, capacitated, and ionophore-treated sperm. Cognitive and daily functioning in older adults with vegetative symptoms of depression. Self reported negative biaxin dose pediatric affect and cardiovascular reactivity were recorded at both sessions. Some of these off-label uses include previously treated aneurysms, acutely ruptured aneurysms, small aneurysms, distal circulation aneurysms, posterior circulation aneurysms, fusiform aneurysms, dissecting aneurysms, pseudoaneurysms, and even carotid-cavernous fistulas.

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Phlebotomy was performed during both the LD(50) and fluid resuscitation studies. H9N2 pre-infection modulated but did not conceal clinical disease by HPAIV H5N1. The effect of the organic solvent on the rate and equilibrium for the synthesis of Z-Asp-PheOMe could be explained by the variation in the partition coefficient. Based on this study, the claims process, particularly medico-legal examinations, and other factors that could impact on injury recovery, are targets for further research, possible policy review, or legislative change. Xanthophore and iridophore pigments both presumably derive from purine precursors. The Basel interdisciplinary clinic for parents with infants and toddlers: concept and empirical results. Marked decreases in lettuce phenolic contents and antiradical activity were found in most of the treatments. Biophysical and pharmacological studies have identified the sodium channel isoforms Na(v)1.3, Na(v)1.7, Na(v)1.8, and Na(v)1.9 as particularly important in the pathophysiology of different pain syndromes. One thousand one hundred forty-four consecutive glucophage drug type eyes of 1144 patients who underwent corneal transplantation between 1992 and 2006. Paclitaxel ester derivatives of adenine-containing triphosphono-gamma-(Z)-ethylidene-2,3-dimethoxybutenolide 8-10 were also synthesized.

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The result showed that the toxicity of runoff in spring was higher than those in summer. Absence of transovarial transmission of Borrelia duttonii, a tick-borne relapsing fever agent, by the vector tick Ornithodoros moubata. Acriflavine being actively bound to DNA is demonstrated not to protect DNA molecule from radiation damage. Our objective was to identify and compare available apps for ear and hearing assessments and consider the incorporation of such apps into hearing screening programs. Comparison of ICE (ifosfamide-carboplatin-etoposide) versus DHAP (cytosine arabinoside-cisplatin-dexamethasone) as salvage chemotherapy in patients with relapsed or refractory lymphoma. Nevertheless, these persons are as many in the practice of all the physicians and their various pathologies concern all the medical specialties. Bronchial asthma, a psychosomatic disease (medical psychology of the asthmatic). However, unlike in children, clinical presentation of foreign bodies in adults often varies with regard to symptoms and signs and occurs without asphyxia. In addition, diet restriction increased locomotor activity in a runwheel cage among mice of both ages but did not affect exploratory activity in a novel arena.

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The control samples were exposed to the same intensity of light generated by a conventional incandescent light bulb. At the same time, no sleep snoring children were include as controls. Together, our findings indicate that MPO-mediated methionine oxidation contributes to bacterial killing by neutrophils. This line when seen in otherwise intact corneas has been presumed to be an autoimmune endotheliopathy. Patients with solitary FVPTCs who underwent thyroid surgery were included. No embolic events occurred in the preoperative or postoperative period. A series of novel sulfone substituted 4,5-diarylthiazoles have been synthesized and evaluated for their inhibition of the two isoforms of human cyclooxygenase (COX-1 and COX-2). The C3N- anion: first detection of its electronic luminescence in rare gas solids.

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