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Copax (Alprazolam)

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Copax is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Copax is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Copax may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alparazole, Alzocum, Alzopam, Anxico, Axizox, Azolam, Calmef, Depwell, Dizeral, Fluti, Indolam, Jolistar, Mebaspa, Mediprex, Oclam, Pranol, Prazil, Prozolam, Sertakem, Sinzolam, Somnirest, Tensyl, Trapose, Visram, Zepro, Zopral, Zotin

Similar Products:
Prograf, Lamisil, Pepcid, Levaquin, Azulfidine, Phenergan, Zanaflex, Altace, Levlen, Fasigyn, Celecoxib, Estraderm, Calmtec, Tricofen, Nifedin,

Also known as: Alprazolam


Copax is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Copax is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Copax if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Copax or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Copax. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Copax XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Copax XR may be habit-forming and should be used only by the person it was prescribed for. Copax XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Copax extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Copax XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Copax XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Copax XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Copax XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Copax XR dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Copax XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Copax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Possible involvement of 5-HT and 5-HT2 receptors in acceleration of gastrointestinal transit by escin Ib in mice. According to the reaction pattern with untreated and enzyme-treated RBCs, the cold-type autoantibodies of patients 2 and 3 were revealed to be anti-Om and anti-I, respectively. There is a positive correlation between the course of periodontal disease and psychosocial stress status. Partially purified FVIII protein fragments were used to produce monoclonal antibodies. This review article examines executive functioning in PT and LBW children, with a specific focus on adolescence and the functional consequences of executive dysfunction in this age group. This is the first and largest study using American College of Surgeons NSQIP to examine 30-day readmission after SLNB and LAD for melanoma in 3 commonly operated anatomical regions. DNA probes developed for Salmonella, Shigella, Campylobacter, and enteroinvasive and enteropathogenic E. Synaptic reorganization occurs in the hippocampus following various forms of seizure activity and injury, and may contribute to epileptogenesis.

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Apoptosis and heart failure: A critical review of the literature. Nerve fibres are rarely observed in the centre of the internal circular layer, although it is possible to see terminal buttons, with neural tubules and vesicular formation. Thirty-two chemicals were significantly linked by covariance with expressed genes. The aim of this study was to identify biomarkers of progression to CRC through metabolomic profiling of human serum samples with a multistage approach. The purpose of this study was to review the clinical outcome and survivorship in rheumatoid arthritis (RA) patients undergoing TKA in hybrid technique with a cementless fixation of the femoral component. Lichen planus pemphigoides is a rare immuno-bullous disorder which usually affects adults.

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Medication use has potential for safety risks if sufficient attention is not paid to contraindications concerning cross allergy. Inferring somatic mutation rates using the stop-enhanced green fluorescent protein mouse. Gross-reactivity between various tumors and streptococcus preparation, OK-432. Studies on the destruction of adrenal and testicular cytochrome P-450 by spironolactone. The results of the present study, no effect of prenatal flutamide, do not support the hypothesis that female rats require prenatal androgen receptor-mediated actions of testosterone in the organization of neural tissues for the occurrence of adult mounting and lordosis behavior. In the blind loop syndrome bacterial overgrowth--accompanied by an increase in bile acid deconjugation--is thought to be responsible for the observed morphological alterations of the small intestinal mucosa with its concomitant malabsorption syndrome. The water content in the protein interior can be modulated by the flexibility of protein elements that interact with water, which can impart positional disorder to water molecules, or bias the pattern of internal hydration that is stabilized. SUVbsa appears preferable to SUVbw, since it is minimally affected by the body size. The use of web-based communication must also be a convenient and naturally incorporated part of both individual and organizational use of the web in general. Information gained from this study should be used to influence ATV public education programs.

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Efficacy of fluconazole on systemic mycosis associated with hematologic malignancies and a study on diagnostic value of plasma beta-D-glucan levels. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. NPY expression was compared with the expression of growth associated protein-43, olfactory marker protein, the low-affinity nerve growth factor receptor (p75) and S-100, factors expressed in the olfactory system at known stages of development. The basic-helix-loop-helix (bHLH) class of transcriptional activators, important in the establishment of many different cell lineages, share two important properties: the ability to heterodimerize with other members of this family and to bind DNA containing the loose consensus sequence CANNTG. This diversity of function is broadly associated with primate phylogeny and does not have a simple relation to coat color phenotype within primate clades. Data were collected from March-April 2011 at eight Flemish nursing homes. Current options for removal of gallstones from the common bile duct include: (1) transcystic choledochoscopic stone extraction, (2) combined laparoscopic/fluoroscopic stone extraction using a helical stone basket, and (3) laparoscopic choledochotomy with T-tube insertion.

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After balloon injury, matrix metalloproteinase (MMP) expression is upregulated. Intracranial pressure (ICP) was monitored in 218 consecutive children with hydrocephalus secondary to tuberculous meningitis (TBM). Fourteen cases of disseminated histiocytosis x (HX) from a 15 year period were studied clinicopathologically. All seven patients reported insomnia due to pain during a mean of 10 months, improved by aspirin or other nonsteroidal anti-inflammatory agents. Levels of glycosaminoglycans in the cerebrospinal fluid of healthy young adults, surrogate-normal children, and Hunter syndrome patients with and without cognitive impairment.

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An N-terminal domain of glucagon molecule (Phe6-Tyr10-Tyr13) could be a certain hydrophobic moiety involved in intermolecular self-association (probably, via helix-helix docking), while a C-terminal domain (Phe22-Trp25-Leu26) seems to critically affect the oligomer size in the off-pathway aggregation of synthesized fusion proteins. Commonly encountered difficulties in pathologic staging of lung cancer. We used fluorescent in situ hybridization to investigate the dynamics of gene association with transcription factories during immediate early (IE) gene induction in mouse B lymphocytes. Chinese patients with PBC from a tertiary center were identified via electronic search of hospital medical registry. The conjugates (LFA-HRP) were applied to aldehyde-fixed, saponin-permeabilized 3T3 cells in pre-embedding labeling electron microscopy. The implication of the tyrosinase assay results in light of the phenotype and the possible location of the pigment block in these forms of OCA are discussed. A highly sensitive proteoglycan-binding assay was developed for the detection and determination of small amounts of hyaluronate. We measured gene expression and drug sensitivity in 15 pediatric T-ALL cell lines to find signatures predictive of resistance to 10 agents used in therapy.

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Biochemical and biological function of Escherichia coli RecA protein: behavior of mutant RecA proteins. Regeneration of Class III furcation defects with basic fibroblast growth factor (b-FGF) associated with GTR. High frequencies of the susceptibility allele could be readily reduced by modern breeding techniques. The liver, spleen, lymph node and skin harvested after the burn secreted significantly higher amounts of IL-6 after tissue culture when compared with those taken from sham rats. 16 surviving patients showed decreasing endotoxin levels and decreasing elastase concentrations during the course of abdominal lavages. This relatively short surface separation distance is consistent with the role of CuA as the immediate oxidant of cytochrome c in the cytochrome oxidase (Hill, B. In a total of 70 malignant melanomas we searched for dendritic-branched fluorescent pigment cells. The CAT activity in normal cells was significantly higher than in Ni-transformed cells, suggesting that the promoter region of thrombospondin was less efficiently transcribed in Ni-transformed cells. However, the distribution of QACs among diverse members of the Plumbaginaceae adapted to different types of habitat indicates that different QACs could have selective advantages in particular stress environments. Parameters of normal polymorphonuclear cell function in patients with repeated gonococcal infections.

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Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. To develop a brief measure of stage of psychological recovery from mental illness by identifying the best-performing items of the 50-item Stages of Recovery Instrument (STORI). We also report that the mutated rhodopsin (P23H) is present in rat rod outer segments from heterozygous animals and that residue 320 in both normal and mutated rhodopsins is threonine, not serine. Furthermore, microsurgical resection of pineal region neoplasms is associated with quite a high morbidity. Hydrocarbon management depends on specific toxicity and viscosity. Extremely high frequency of autoimmune-predisposing alleles in medieval specimens. From these transfectants we retrieved gene P1A which transferred the expression of both P815A and B. An extremely localized bereitschaftspotential showing approximately the same latencies and amplitudes was simultaneously recorded from the frontal eye field and supplementary motor area (SMA). Exposure to arsenic significantly depleted delta-aminolevulinic acid dehydratase (ALAD) activity, reduced glutathione (GSH) level, superoxide dismutase (SOD) and increased thiobarbituric acid reactive substance (TBARS) activity in red blood cells.

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For this purpose, the product of the green and blue channels of the RGB retinal images is considered and after a median filtering stage, it is used as a PDF for tracking procedure. Errors were especially likely (17/51) in patients who had had marrow involvement or those who had anemia, leukopenia, or thrombocytopenia. Variation in cognitive outcome was related to certain subject variables. Active specific immunotherapy as an adjunct to the treatment of metastatic solid tumors: present and future prospects. A higher than expected incidence of hepatitis B antigen positives has been noted in Northern Territory donors. These data suggest that one mechanism by which intravenous nitroglycerin improves ischemia in acute coronary artery disease syndromes may be by inhibition of platelet thrombus formation and may highlight the potential importance of reduced thiol in this mechanism. Primary immunodeficiency 1991: new uses and prospects of genetic counseling.

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The studies on the effect of nalidixic acid (negram) on the synthesis of DNA and determination of its minimal inhibitory concentrations revealed a regular decrease in the sensitivity levels to negram of the tetracycline resistant mutants selected on media with tetracycline. ADC maps obtained from high b value DWI might be a better imaging biomarker in the preoperative evaluation of gliomas. A more frequent increase in IgE and measles antibodies was found also while the normocomplementary multiple sclerosis patients more frequently had higher levels of IgA. Control experiments based on binocular injections of tetrodotoxin (TTX) demonstrated that no gradients were present in the baseline activity within the layers. The radiographic findings were classified as osteosclerosis, osteopenia, intermittent growth lines, diaphyseal widening, or soft-tissue ossification. Here, we consider not only genetic and epigenetic mechanisms, but also inflammation and cell state reprogramming in creating tumor heterogeneity. Despite concerns that excessively strong siRNA binding could prevent the discharge of siRNA from its carrier, higher affinity continually led to stronger silencing. A total of 36 patients with CML were selected, 46 tofranil patient reviews healthy persons were used as normal controls. The histopathological findings showed endometriosis and inflammatory changes of uterine appendages. Cellular zinc and redox buffering capacity of metallothionein/thionein in health and disease.

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Despite technical challenges, virtual-environment surgical planning is useful as a clinical tool for preoperative visualization, cephalometric analysis, and surgical intervention. Accordingly, ASO-mediated silencing of Wisper in vivo attenuated MI-induced fibrosis and cardiac dysfunction. A considerable dissociation was observed between subjective effects and effects measured by ergometer test in the individual patient. A guide to understanding and implementing risk evaluation and mitigation strategies in organ transplantation. In this study we analyse the value of high frequency ultrasound as diagnostic tool in non-palpable breast nodules (NPBN). Variants lacking all, or all but two, repeats were active with similar specific activity and the same bile salt dependence as the native milk enzyme. In particular, it raises the question of why prevalence and infection rates seem to be disproportionately higher in Matabeleland relative to other provinces of the country. Patients with colorectal adenoma polyps (PLPs) are at higher risk for developing colorectal cancer (CRC).

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It may provide WBC-reduced platelet concentrates without the additional cost of filters. A gradually expanded PCV13 national immunization program was launched in 2013 in Taiwan. It is shown that the spatial-temporal correlation depends entirely on the temporal correlation of the signal exiting the diffuse field, or alternatively on its power spectral density. Human and mouse show markedly different sensitivities toward bacterial endotoxins, and recent evidence suggests that a species-specific regulation of the lipopolysaccharide receptor Toll-like receptor 4 (Tlr4) may contribute to this phenomenon. The data on the hearing findings and morphometrical evaluation of the cases with bilateral tinnitus may be important for anatomists and clinicians.

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Applicability of the Ben-Tovim Walker Body Attitudes Questionnaire (BAQ) and the Attention to Body Shape scale (ABS) in Japanese males and females. Elevated serum retinol-binding protein 4 levels are correlated with blood pressure in prehypertensive Chinese. The results of 10.000 individual tests have shown that it is necessary to revise and supplement the influences and the emergence of new antigens support this demand. The aim of the study was to evaluate the results of treatment in patients with infected fractures or chronic osteomyelitis in the tibial and ankle regions by radical debridement of skeletal and soft tissues and coverage of the defect, using free flap transfer or muscle flap transposition. The initial blood concentration values ranged within the physiological limits and were not therefore essentially influenced by gynecologic diseases. One of these patients had a splenectomy, with no evidence of disease.

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Density gradient electrophoresis of mouse spleen lymphocytes: separation of T and B cell fractions. Mean values of the annual increment of body height and the ages of the pubertal growth periods were analyzed. More than 50 million Americans display blood pressures outside the safe physiological range. Genomic and residual networks were compared between Dent and Flint. Normal deliveries were compared with cases of fetal retardation and moderate acute fetal acidosis.

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We recently reported that Clstn2 knockout mice (Clstn2-KO) have a deficit of GABAergic interneurons coupled with hyperactivity and deficient spatial memory. A number of its actions make it a potential anti-cancer agent, including cell cycle regulation, interaction with type II estrogen binding sites, and tyrosine kinase inhibition. Angioarchitectonicly, too, the pars superior is fundamentally different from subsequent sections of the duodenum since it is vascularized from two sides, i.e., the vascularization here is still of a typically gastric character. Apathy in a sunburnt country: Understanding the skin cancer and sun protection knowledge and practises of Australian doctors. When the hapten was coupled to a T-independent antigen (streptococci) a restricted immune response of IgM and IgG antibodies was induced. Data were collected from 818 patients (from 273 centers across Germany) who were pretreated with slow-release luteinizing hormone-releasing hormone (LHRH) agonist formulations and who were about to be switched to the leuprorelin implants. Changes in the peritoneum of the small intestine and diaphragm in experimental portal hypertension. Base transition and transversion was not found only in 5.8S sequences, 2 sites transition and 1 site transversion were found in ITS1 sequences, only 1 site transversion was found in ITS2 sequences comparting the ITS sequences data matrix.

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The remaining three lines expressed mRNA for IL-6, but did not secrete IL-6 protein. Inhibition of invasion of both passages through Matrigel-coated filters was seen at low seeding density, while at the high seeding density, EGF enhanced invasiveness. Measurement of OPN might be useful for evaluating the outcomes of various clinical interventions for obesity-related cardiovascular diseases. Preliminary experiments allowed us to select the more suitable couple of CDs composed of sulfated-alpha-CD and hydroxypropylated-beta-CD. Motility-modifying agents and management of disorders of gastrointestinal motility. Transplantation: The promise of co-stimulatory blockade in transplantation. Renal transplantation in these cases is sometimes avoided because of implied urologic and infectious complications, and the early loss of the homograft. Associations between management practices and colostrum quality on New Zealand dairy farms. Findings suggest relaxation and peripheral vascular circulation are inversely related to the intensity of tinnitus symptoms. Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries.

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Study of metabolic processes and the pathogenetic treatment of patients with the post-gastric resection syndrome. An increase in susceptibility to infection in an untoward effect common to nearly all immunosuppressive agents. The nucleotide sequence of the gene rpsD for the ribosomal protein S4 of three thermosensitive mutants of Escherichia coli K12 was determined. There were analyzed in a retrospective way the results of pre-retrieval hormonal levels as well as the number of retrieved oocytes, mature oocytes and transferred embryos in three groups of patients (2 GIFT, 1 IVF-ET) which achieved a pregnancy, and were matched with groups with no pregnancy. Xylitol, an energy source for intravenous nutrition after trauma. Rehabilitation of severe maxillary atrophy with zygomatic implants. As of 3 October 2012, the performance of 28 single-sequence and 13 comparative methods has been evaluated on RNA sequences/structures released weekly by the Protein Data Bank.

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Concomitant off-pump coronary artery bypass grafting results in improved in-hospital outcomes for patients with ischemic mitral regurgitation undergoing surgery. TNF and interleukin-1 actions are typically terminated by desensitization, and I kappa B-alpha reappearance normally occurs within 30-60 min. Earlier work revealed that mice with knockout of the G-protein coupled receptor Gprc5a develop late onset lung tumors including LUADs. The developed synthetic strategy was adopted to prepare glyburide 5mg cost a related 1,2-bis(2-hydroxybenzamido)benzene-derived ligand. The necessity of performing the anatomic classification of ano-rectal fistula should be emphasized.

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A project designed to improve the quality of health care received by persons with psychosis is described. We tested the hypothesis that phase-delayed circadian rhythms underlie seasonal affective disorder (SAD) by measuring phase position of 6-sulfatoxymelatonin excretion and comparing antidepressant response to morning or evening light given as a first treatment. This analysis revealed that the presence of both the pac1 and pac2 elements was both necessary and sufficient for the induction of high-frequency recombination events by the alpha sequence. As demonstrated by these results, the presence of beta CD in the culture medium in a dose of 0.1 ml/l in the growth deceleration phase causes a tenfold increase in the synthesis of pertussis toxin by microbial cells in comparison with conditions characterized by the absence of beta CD. TFMSA cytoxan dosing /TFA/p-cresol were used as cleaving reagent in all peptide-resin (1-11) cleavage. Patients who had undergone craniocervical decompression (CCD) were grouped by method of dural closure.

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Identification of chemical components in Baidianling Capsule based on gas chromatography-mass spectrometry and high-performance liquid amaryl 1 mg cost chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry. Costs of a community-based glaucoma detection programme: analysis of the Philadelphia Glaucoma Detection and Treatment Project. The role of cell division in the spontaneous development of antisheep PFC in cultures of mouse peritoneal cells has been studied. The concentration of acetoacetate decreased significantly on the first day of fasting to values that were 4 times as high as the initial value. We used a hybrid technique combining two independent methods of fat suppression. Multivariate analysis of prognostic factors was performed by a regression model incorporating long-term survivors with the Weibull distribution. The production of matrix metalloproteinase (MMP)-13, nitric oxide (NO), tumour necrosis factor (TNF)-alpha and IL-1beta were also enhanced, although less intensely. Here, we investigated the further reorganization of membrane rafts in cultured epithelial cells and ex vivo isolated nasal cells after infection with rhinoviruses. Effects of seaweed-restructured pork diets enriched or not with cholesterol on rat cholesterolaemia and liver damage.

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Chaotic and irregular bursting electrical activity in mouse pancreatic B-cells. Development and validation of dietary assessment methods for culturally diverse populations. Based on literature-contingent considerations of safety, efficacy, cost efficacy, and cost neutrality, we conclude that SCS should not be considered a therapy of last resort for CRPS but rather should be applied earlier (e.g., three months) as soon as more conservative therapies have failed. Adult Traumatic Inferior Hip Dislocation: Rare Case Ended with Open Reduction. The organism is usually susceptible to tetracycline, chloramphenicol, aminoglycosides, trimethoprim-sulfamethoxazole, and carbapenems. Effect of addition of tramadol to one MAC sevoflurane on the haemodynamic response to laryngoscopy and tracheal intubation. Itemizing enzyme ligand interactions in native and and half-active hybrid aspartate transaminase to probe site-site relationships.

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