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Calan

Calan is used to treat hypertension, to treat angina, control some types of irregular heartbeats. Calan is a phenylalkylamine calcium channel blocker. It results in relaxation of the arterial muscles, improved oxygen delivery to the myocardial tissue, and decreased total peripheral resistance, systemic blood pressure, and afterload. Calan also decreases the conduction of electrical impulses through the heart that control the coordination of contraction, this slows the rate of contraction.

Other names for this medication:
Calaptin, Covera, Isoptin, Vasopten, Veramil, Verapamil, Verelan, Verpitos, Zolvera

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Also known as: Verapamil

Description

Calan is in a group of drugs called calcium channel blockers. Calan is used to treat hypertension, angina and certain heart rhythm disorders. It works by relaxing the muscles of your heart and blood vessels. Calan is also known as Verapamil, Calaptin, Isoptin, Verelan, Bosoptin, Covera-HS.

Dosage

This section provides information on the proper use of a number of products that contain verapamil. It may not be specific to Calan SR. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet .

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .

Swallow the extended-release tablet whole with a full glass of water. Do not break, crush, or chew it. It is best to take this medicine with food .

If you cannot swallow the verapamil extended-release capsules, you may open it and sprinkle the pellets contained in the capsule on one tablespoon of applesauce. This mixture must be swallowed immediately with a glass of cool water. The applesauce should not be hot and should be soft enough to be swallowed without chewing. Do not chew or crush the pellets .

If you are taking the extended-release tablets, you may sometimes notice what looks like a tablet in your stool. This is the empty tablet shell that is left after the medicine has been absorbed .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (tablets): Adults—The usual dose is 80 to 120 milligrams (mg) three times a day. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets, 24 hr): Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For heart rhythm problems: For oral dosage form (tablets): Adults—The total usual dose is 240 to 480 milligrams (mg) divided in three or four equal doses per day. Children—Use and dose must be determined by your doctor . For high blood pressure: For oral dosage form (tablets): Adults—At first, 80 milligrams (mg) three times a day. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release capsules): Adults—At first, 200 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once daily in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor . For oral dosage form (extended-release tablets, 24 hr): Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor .

Overdose

If you overdose Calan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Calan overdosage: slow heartbeat, fainting fit.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Calan dosage information

Side effects

The most common side effects associated with Calan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of verapamil in the elderly. However, elderly patients are more likely to have age-related heart, liver, or kidney problems which may require an adjustment of dose in patients receiving verapamil .

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The amount of hyperkeratosis, invasiveness and degree of differentiation seem to be responsible for variations in fluorescence intensity. It is possible to design a real time in vivo controlling system for laser tissue thermal interaction that utilizes the changes in the scattered light pattern. Even if it compacted more than a gel that was originally at a high collagen concentration, a gel that started at a low collagen concentration remained less stiff than the higher-concentration gel. Four repetitive DNA sequences cloned from the barley (Hordeum vulgare) genome and common for different Triticeae species were used for a molecular study of phylogenetic relationships among 28 Elymus species. Involvement of the inferior vena cava (IVC) by testicular neoplasms is unusual and often clinically unsuspected. A single addition of oxytocin increased contractility, however, this was not related to maternal BMI. Twenty-two patients with previously untreated carcinoma of the uterine cervix were treated by para-aortic nodal irradiation for the macroscopical metastases found at the operation with or without pathological confirmation, at the National Cancer Center Hospital from 1962 to 1980. Youths with normative to clinical levels of internalizing problems (IP) and externalizing problems (EP) watched emotionally evocative film-clips while having heart rate (HR) recorded, and reported subjective feelings. The task group also proposed a definition of breakthrough pain, and some diagnostic criteria for breakthrough pain. Mice in which the Stat5a/b locus has been inactivated specifically in hepatocytes display GH resistance, the sex-specific expression of genes associated with liver metabolism and the cytochrome P-450 system is lost, and they develop hepatosteatosis.

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Despite the requirement of all three nucleoporins for accurate NHEJ, only Nup153 is needed for proper nuclear import of 53BP1 and SENP1-dependent sumoylation of 53BP1. Even when presented for a subthreshold duration, faces were processed differently to images of objects at an early stage of visual processing. The unique characteristics of each system revealed in this study should guide system choice. In this cross- albenza sectional descriptive study, quantitative content analysis of earned print news items was carried out using predetermined codes related to areas of tobacco control policies. Telomere length correlates with disease severity and inflammation in sickle cell disease. Properties of anthranilate hydroxylase (deaminating), a flavoprotein from Trichosporon cutaneum. Mercury accumulation in Lethrinus nebulosus from the marine waters of the Qatar EEZ. Trends in mortality by pay grade reveal that health inequalities steadily widened between 1974 and 2004. Warning About the Use of Critical-Size Defects for the Translational Study of Bone Repair: Analysis of a Sheep Tibial Model. Two hundred greater saphenous veins in 200 patients and 10 cadavers were investigated.

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The relative risk of CVD mortality of 1.51 (95 per cent CI (1.29, 1.77)) for the Irish was reduced to 1.35 (95 per cent CI (1.14, 1.58)) by the same adjustments. The DNA in eukaryotic cells is packaged into chromatin, which functions as a boundary to the transcriptional activation process. Some important influencing factors such as socioeconomic status, educational background, and cross-cultural perspectives have previously been found to be associated with attitudes toward loud music and the use of hearing protection. When the MTD of vinorelbine had been determined, the doxorubicin dose was then escalated by 10 mg/m2 with the vinorelbine dose held at its MTD. We conclude that mixed type of total anomalous pulmonary venous connection can be accurately diagnosed by echocardiography and Doppler colour flow imaging. Reinfection with a different Vi-phage type of Salmonella typhi in an endemic area.

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