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Amurol (Amoxicillin)
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Amurol

Amurol is a penicillin-like (beta-lactam) antibiotic. It belongs to the most widely-used group of antibiotics available. Amurol is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics.

Other names for this medication:
Acimox, Alfamox, Almodan, Aloxyn, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicilina, Amoxiline, Amoxisol, Amoxivet, Amoxypen, Amurol, Bimoxan, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Hidramox, Hydramox, Larotid, Lupimox, Moxicillin, Novamoxin, Ospamox, Penamox, Penimox, Polymox, Raylina, Sintedix, Solciclina, Sumox, Tolodina, Utimox, Velamox, Wymox, Zimox

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Lamictal, Chloromycetin, Altace, Detrol, Feldene, Astelin, Exelon, Convertin, Fladystin, Cefobid, Cidogrel, Piokap, Embeline,

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Also known as: Amoxicillin

Description

Amoxicillin is used to treat bacterial infections in many different parts of the body. It is also used with other medicines (e.g., clarithromycin, lansoprazole) to treat H. pylori infection and duodenal ulcers.

Amoxicillin belongs to the group of medicines known as penicillin antibiotics. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Children and Adolescents 2 years and older (standard-dose therapy): 45 mg/kg/day PO in divided doses every 12 hours is the standard dose for children with uncomplicated disease that is mild to moderate in severity who do not attend daycare and who have not been treated with an antimicrobial agent in the previous 4 weeks.

Children and Adolescents 2 years and older (high-dose therapy): 80 to 90 mg/kg/day PO in divided doses every 12 hours (Max: 2 g/dose) is recommended for children in areas with high rates of S. pneumoniae resistance (more than 10%, including intermediate- and high-level resistance).

Children younger than 2 years should be treated with Amurol; clavulanic acid, not Amurol alone.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amurol are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amurol.

Crystalluria, in some cases leading to renal failure, has also been reported after Amurol overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amurol crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amurol. Amurol may be removed from circulation by hemodialysis.

Storage

Store this medicine at room temperature, away from heat, light, and moisture.

Side effects

The most common side effects associated with Amurol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Dialysis, renal failure, renal impairment.

Use Amurol with caution in patients with renal impairment as the drug is substantially eliminated via renal mechanisms. Adjust dosage intervals in patients with CrCl 30 mL/min and in patients with renal failure. Dosage adjustments are also recommended for patients receiving dialysis. Do not use the extended release tablet in patients with CrCl 30 mL/min.

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