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Amiwel (Amitriptyline)

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Amiwel is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amiwel is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Amiclozor, Amicon, Amimax, Amitin, Amitop, Amitrac, Amitriptyline, Amitrix, Amitryptyline, Amitwix, Amiwel, Amixide, Amsha, Anitryp, Axtrip, Endep, Eptanol, Gentrip, Goldep, Libral, Librodep, Limbitrol, Maxitrip, Nextrip, Psycomer, Relidep, Ronet, Sarotena, Sereval, Tadamit, Tridep, Typlin, Zodep

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Also known as: Amitriptyline


Amiwel target is the treatment of depression. Amiwel is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amiwel is Amitriptyline. Amiwel is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amiwel are Amiwel, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amiwel dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiwel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amiwel if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amiwel if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amiwel is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amiwel is not approved for use by anyone younger than 12 years old.

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Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation. A second example of mutually isolated medical literatures related by implicit, unnoticed connections. Addition of anaerobic cultures and prolonged incubation times led to an increase in the detection of shunt infections. Consistency in the supply of larval fishes among coral reefs in French Polynesia. sCD83-treated grafts demonstrated normal histology beyond POD140, including dramatic reductions in tubular atrophy and interstitial fibrosis compared with untreated recipients. Given the urgent needs of students with TBI, validating these promising practices should be a high priority for the field of pediatric brain injury. Exploration of health dimensions to be included in multi-attribute health-utility assessment.

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Photometric determination of alpha-tocopherol acetate as iron-3-hydroxamic acid-complex. To model the contribution of pro- and antiapoptotic signaling cascades downstream of activated 5-HT(1A) receptor in cell survival, Chinese hamster ovarian (CHO) cells were employed that exogenously overexpress 5-HT(1A) receptors. Prevalence and prognosis of patients with heart failure in Tokyo: a prospective cohort of Shinken Database 2004-5. That is, even if the path number is reduced by half, error probability is found almost zero. The electron affinity of 2.232 eV and the characteristic photodetachment spectrum is also predicted to be suitable for experimental investigations. The mean CTDIw for the 14 scanners was 60.0 mGy, while the mean Dmid was 45.8 mGy. We were unable to explain why the expressions of IEGs were similar between both doses of MA after chronic administration, although these differed after the single treatment. Our present results demonstrate that NDRG2 participates in oxLDL-induced macrophage activation and modulates ERK1/2-dependent PDGF and VEGF production, which has potential application in atherogenesis.

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In this study we demonstrated the utility of 70-mer oligonucleotide microarrays for genotyping of Campylobacter jejuni isolates, with resolution outperforming MLST. In addition, the closely related technique known as cost-effectiveness (C-E) analysis is described and contrasted with cost-benefit analysis. Direct measurements were performed in 100 units by using the thermoluminescent detectors and X-ray films. Our findings suggest that the heterogeneous epigenetic dysregulation of promoter methylation in various genes is interrelated with the occurrence of mutations, as manifested in epigenetic-genetic subgroups of tumors. The paper presents a general overview of the use of nanoparticles to perform sample preparation. STATEMENT OF SIGNIFICANCE: pH-responsive drug delivery system could release drug efficiently in targeted acid environment and minimalize the amount of drug release in normal physiological environment. In the first 20 ms, instantaneous eye acceleration was in the direction of target motion but did not depend on other visual properties of the stimulus. Both LTA and LPS significantly induced several cytokines with LPS eliciting more potent effects. In addition to the industrial and vehicular pollution, the agricultural pollution due to the burning of wheat and rice straws by the farmers should also be checked because it also creates tremendous pollution in the atmosphere. Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction.

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Treatment of myasthenia gravis: current practice and future directions. Their deposits in the intestine of patients with CD with severe enteropathy are considered specific for this condition. Conjugated Polyelectrolyte-Based New Strategy for in Situ Detection of Carbon Dioxide. Frequency of complications of mitral valve prolapse in subjects aged 60 years and older. Electroconvulsive therapy (ECT) procedures require the work of a multidisciplinary team that includes an anesthesiologist, a psychiatrist, and a treatment nurse. Accumulation of DSBs in gamma-H2AX domains fuel chromosomal aberrations. A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation.

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The LC method is carried out on a Luna C(18) column (150 x 4.6 mm) maintained at 40 degrees C. A 47-year-old woman underwent gasless laparoscopic-assisted sigmoid colectomy. Quantity of SECs may be a useful quality measure of induced sputum from young children with pneumonia. In clear unmarked areas, silicone rubber tubes were damaged with the pulsed pattern when exposure reached 50 W for 1 s. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes.

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This fortuitous discovery enabled researchers to develop agents which could inhibit receptor-mediated tumor cell signaling. Our results suggest that OsCO3 primarily controls flowering time under SD conditions by negatively regulating Hd3a and FTL expression, independent of the SD-promotion pathway. THE CONSERVATIVE TREATMENT OF FRACTURES OF THE LONG BONES AND OF WOUNDS COMPLICATING THEM-A PAPER IN ORTHOPEDIC SURGERY. Both the 400 and 500 Hz excimer laser systems were safe and effective for the LASIK treatment of moderate-to-high hyperopia. Single doses of alpha-GalCer, alpha-C-GalCer, or OCH were sufficient to prevent liver metastasis and subsequent doses failed to elicit optimal cytokine responses. Furthermore, we indirectly compared dose-response relationships across studies and not from single controlled studies. The pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background. Evidence against transferrin as a binder of either vitamin B12 or folic acid. In these analyses, the hVISA phenotype occurred in more than one-quarter of MRSA IE isolates, was associated with certain IE complications, and varied in frequency by geographic region. Conjugated linoleic acid activates AMP-activated protein kinase and reduces adiposity more effectively when used with metformin in mice.

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This simple clinical maneuver at the end of surgery reduced shoulder pain as well as postoperative nausea and vomiting after laparoscopic surgery by more than half. As depression is often characterized by hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis, we conducted does protonix affect drug test the present study to further investigate the individual differences in the HPA axis response and glucocorticoid receptor (GR) protein expression and translocation between susceptible mice and resilient mice. Difficult etiologic diagnosis of mediastinal adenopathies appearing during tuberculosis. Power analysis predicts that a 1-point difference on this 5-step scale would be detectable with 12 subjects in each of two defined groups. The plasma concentration of torasemide was determined as a function of time in 8 patients with impaired renal function (creatinine clearance less than or equal to 25 ml/min). In vitro fertilization with pre-implantation genetic diagnosis may help in preventing miscarriage from recurrent polyploidy but is not so valuable for recurrent trisomies. Asymptomatic low ankle-brachial index in vascular surgery patients: a predictor of perioperative myocardial damage. Between November 2005 and January 2008 100 consecutive patients were scheduled to undergo robot-assisted laparoscopic aortoiliac procedures.

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RATE LIMITS FOR MISPAIRING AND COMPENSATORY CHANGE: THE MITOCHONDRIAL RIBOSOMAL DNA OF ANTELOPES. Adult patients with a diagnosis of iron-deficiency anemia were enrolled for upper endoscopy with duodenal biopsies. Prevention of drug hepatotoxicity includes increased vigilance during pre-clinical drug development and clinical trials, alanine prometrium capsule oral aminotransferase monitoring with certain drugs, better marketing strategies, and the future identification of both diagnostic and prognostic biomarkers. Our results provide evidence that the BmArmi and BmYb coexist with BmVasa and play an important role in perinuclear nuage granules formation in ovary-derived BmN4 cell. Characterization of the anaerobic propionate-degrading syntrophs Smithella propionica gen. Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study. It focuses on imaging findings that may deserve immediate surgical intervention. Operative and postoperative measures, resection margins, complications, and survival outcomes were evaluated. The model supports current diagnostic sampling approaches and control measures for the removal and destruction of nervous system tissues in slaughtered cattle. After cleaving with different cleavage reagents, the peptide with an excess of N-terminus and with an un-amidated C-terminus stopped the activity while the peptide with an excess Asn at the C-terminus had the activity level the same as natural CMIV.

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Neurochemical markers calcitonin gene-related peptide, substance P were decreased in medullary dorsal horn ipsilateral to the injury side, whereas substance P receptor NK1 expression was increased after 8 days. The purpose of this case report is to illustrate the use of continuous passive motion machines in the treatment of severe knee flexion contractures. albicans, yet possesses a much wider metabolic repertoire than any of the yeasts studied in this work. To evaluate the flexural strength and rotating fatigue resistance of direct and indirect resin composite restorative materials. Impaired Autophagy and Defective T Cell Homeostasis in Mice with T Cell-Specific Deletion of Receptor for Activated C Kinase 1. and Weston and Watkins) that parallelize the computation evenly over the number of classes.

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Subtracted datasets, using pixel-by-pixel subtraction of the post-contrast images from the pre-contrast images, were created from the 64 detector-row CT of patients undergoing three-phase examination of the liver (unenhanced, arterial phase, and portal venous phase). Complete information regarding different magnetic interactions, namely, principal components and orientation of principal axis system with respect to the molecular frame, can be derived from orientation selective pulsed EPR measurements that are performed at different magnetic field positions within the inhomogeneously broadened EPR spectrum. However, due to the high levels of basal bone mass in Shn2 deficient mice, the bone mass levels after ovariectomy were still comparable to sham operated wild-type mice. A decrease in Bcl-2/Bax ratio with increased expression of Apaf-1 and caspase-3, and cleavage of poly(ADP-ribose) polymerase provide compelling evidence that nimbolide-induced apoptosis is mediated by the mitochondrial pathway. Mild dementia, spastic gait and hyperreflexia were observed on neurological examinations. However, many of the earlier CPT derivatives were either too toxic for clinical use or had very poor pharmacokinetics. Our experiments show that barn owl biomotion-based trajectories consistently improve scan accuracy when compared to intuitive scanning motions. Results: Seven studies, with 8 datasets comprising 530 participants with T2DM and 549 non-T2DM controls, were included. The interactive effects decreased to non-significance after what is generic xanax look like controlling for depressive symptoms and hopelessness. During 50 watt exercise however, an increase of the diastolic PA pressure has been observed simultaneously with a diminution of cardiac output (stroke volume being constant).

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