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Alzac (Alprazolam)

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Alzac is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alzac, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alzac is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aldep, Aldip, Alflux, Alpaz, Alprose, Anxitab, Belfa, Benzax, Benzolam, Besquil, Cardilax, Censir, Dizeral, Eurolam, Exiten, Fluzolam, Mcalm, Nucalm, Oclam, Omelam, Optizole, Ozolam, Procalm, Prosanti, Prozam, Resto, Setlan, Suzilam, Tenan, Zocam

Similar Products:
Strattera, Loxitane, Desyrel, Clomid, Noroxin, Exelon, Silagra, Plavix, Eldepryl, Chloramsone, Amitrim, Metclam, Cefdinirum, Cardival, Loette, Recamicina,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alzac dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alzac XR dosage information

Side effects

The most common side effects associated with Alzac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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In this study, the results achieved by residential care programs for minors were evaluated. We report a case of spontaneous embolization to the right cerebral circulation from a severely regurgitant, calcified bicuspid valve. Evaluation of the quality of proteins of various vegetable grains used in various biological methods. A series of 38 cytological samples from the larynx, obtained with a replica method, is presented. In destructions of vertebrae due to tumors, the extent of bone destruction and the altered position of the vertebrae in relation to each other can be imaged. Septic abortion is a frequent cause of maternal death in our patient population. FgSrp1 localized to the nucleus and interacted with FgPrp4 in vivo.

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Extracontractual referrals in first three months of NHS reforms. We also searched five trials registry databases, and checked reference lists of included studies and reviews for further references to relevant randomised controlled trials (RCTs). Bacterial pathogen-associated molecular pattern molecules (PAMPs) such as LPS activate the endothelium and can lead to lung injury, but the signaling pathways mediating endothelial injury remain incompletely understood. Age and the clinical profile of idiopathic mitral valve prolapse. We report a case of a young man with widely metastatic testicular stromal cell tumor who achieved complete clinical remission following chemotherapy with etoposide, ifosfamide, cisplatin, and bleomycin. The aim of this study was to investigate structural alterations in the hippocampus (HIPP) and amygdala (AM) following conventional rTMS in patients with depression. It is known that glucagon administration elicits ACTH and cortisol responses in humans, although this effect takes place after intramuscular or subcutaneous but not after the intravenous route of administration. Amniocentesis under permanent ultrasonic control--advantages of a special procedure. The contractions by K,ACh and Ba are exponential in shape, but consisted of phasic contraction (PC) and the subsequent tonic contraction (TC). We preferred a non-surgical, organ-sparing treatment which started with chemotherapy followed by radiation.

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We identified published equivalence trials in the venous thromboembolic disease, by a systematic search in Medline. Expression of (His)(6)-eIF3s4 fusion protein in human breast cancer cell Bcap37. The higher the pK(a) of the substrate, the higher is the reactivity. Large geographic variation exists in oral anticoagulation use in atrial fibrillation. Remission of membranoproliferative glomerulonephritis type I with the use of tacrolimus. YrrB is a hypothetical protein containing a tetratricopeptide repeat (TPR) domain from a Gram-positive bacterium, Bacillus subtilis. Accumulated evidence suggests a direct effect of vitamin D and its metabolites on uremic bone. 378 larvae from plain and lowland rivers, also in the northeast and central regions, were identified as Nkusi, Kisiwani and Kibwezi forms. Gelation of deoxygenated solutions of sickle-cell human Hemoglobin (HbS) is of high theoretical interest and it has serious pathological consequences.

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The antagonistic effects of IFN on IL-4-mediated responses prompted an examination of the effects of IFN on the host response to Nb. Purification and characterization of adenylyl cyclase from Bacillus anthracis. A lipid-loading test of ORP-Tg mice revealed reduced triglyceride uptake, which mainly was due to suppressed uptake of very low-density lipoproteins. In this design, with a rare event, all the events are selected for risk-factor assessment. Determining the drivers of population structure in a highly urbanized landscape to inform conservation planning.

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The microvilli became attached to the fibrin threads in an initial period of fibrinolysis. As revealed by autoradiography after labeling with tritiated thymidine and uridine, the lymphoid infiltrate had a low rate of proliferation and a normal or enhanced synthetic activity of ribonucleic acid. Observables such as two-photon absorption cross sections cannot be computed from the wave functions of initial and final states alone because of their nonlinear nature. The method can be applied on any programmable FT-NMR spectrometer and is demonstrated here on micromole quantities of sample in a standard 5-mm NMR tube. Clinical practice guidelines recommend temsirolimus for use in treatment-naive patients with poor-prognosis metastatic RCC of any histology (predominant clear cell or non-clear cell histology). We used binary logistic regression to assess characteristics associated with immunization and bivariate analyses to compare refugee immunization rates with those of the general US population. Observations on the choice of reconstruction matrix in magnetic resonance imaging. Here we report the molecular identification of membrane-bound glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (mPGES), a terminal enzyme of the cyclooxygenase (COX)-2-mediated PGE(2) biosynthetic pathway. Structural differences in the heavy chains of rat ventricular myosin isoenzymes. Ninety-three percent preservation of morphological left ventricle function in 15 years of follow-up supports the concept of anatomic correction.

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Pharmacodynamics of simulated total versus free-drug serum concentrations of a low versus a high protein bound third-generation oral cephalosporin (Cefpodoxime versus cefditoren) against Streptococcus pneumoniae. Stereotactic ablative radiotherapy (SABR) has improved the survival for medically inoperable patients with peripheral early-stage non-small cell lung cancer (NSCLC). Hand therapy interventions, outcomes, and diagnoses evaluated over the last 10 years: A mapping review linking research to practice. Evidence for a causal relationship between presence of Helicobacter pylori (H. Two types of oestrogen receptor, alpha and beta, add the second variable susceptible to modulating the response to receptor activation. It is concluded that the quality of the histone-DNA interactions at the promoter makes an intrinsic contribution to the regulation of the gene. IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN-gamma production by NK cells.

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At the 1-year follow-up visit, compared with participants without prediabetes, participants with prediabetes had the greatest improvements in physical functioning. The authors present a stepwise method of assessing and treating peroneal intraneural ganglion cysts. The mutation beta 99 Asp-Tyr stabilizes Y--a new, composite quaternary state of human hemoglobin. Experience of the surgeon combined with careful surgical handling are of great importance for success in this technique. One approach to deliver pharmacophores is by conjugation to the lipophilic triphenylphosphonium (TPP) cation that accumulates in mitochondria driven by the membrane potential.

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Alternative role for prolactin-releasing peptide in the regulation of food intake. Twenty-four male Sprague-Dawley rats were randomly divided into four groups and designated as exhaustive exercise only (E), exhaustive exercise with low dosage (EL), medium dosage (EM) and high dosage (EH) GT at 0, 0.1875, 0.9375 and 1.875 g/kg/day, respectively. Depressive disease: basal cortisol levels and demographico-clinical variables. Multivariate statistical methods were used, including Cluster Analysis, Principal Component Analysis and Multivariate Analysis of Variance. Although antipsychotic medications can alleviate the psychiatric symptoms of patients with schizophrenia, the treatment effect for both positive and negative symptoms would be even more effective if it is combined with horticultural therapy. Flupenthixol was given in a dosage of 0.5 to 2 mg a day, diazepam in a dosage of 2.5 to 10 mg a day and sulpiride 100 to 200 mg a day, in identical capsules. Hyperexcitable nociceptive neurons also activate satellite glial cells in the TG and microglial cells and astrocytes in the Vc and C1-C2. Blood samples were collected before (baseline) and 24, 120 and 192 hr after the anesthesia.

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Utilizing several independent markers for blood vessels, inflammatory processes and neural activity in the vHPC, we found that SL/vulnerable rats exhibit increased neural activity, vascular remodeling and inflammatory processes that include both increased blood-brain barrier permeability and increased number of microglia in the vHPC relative to control and resilient rats. The gene was cloned using a genomic fragment during a chromosomal walk upstream of the AP3 gene located at chromosomal location 79CD on the left arm of the third chromosome (Kelley, M.R. 3 year outcome of percutaneous endoluminal closure of persistent ductus arteriosus. New version of LSTSIM for computer simulation of Amblyomma americanum (Acari: Ixodidae) population dynamics. Insulin and glucagon secretion by pancreatic islets from nondiabetic and diabetic sand rats (Psammomys obesus). A GC/MS method was used for the identification of anabasine as the main constituent in the leaves, food extract, blood, and the urine of the deceased. The survival period of skin homografts in cyclophosphamide treated group was significantly increased (P less than 0.01) in rabbits, but there was insignificant increase in rats (P greater than 0.01). This cross-sectional population-based survey was conducted to determine the incidence of workplaces injuries and assess the magnitude of some important risk reduction practices among workers.

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Childhood cyanotic breath-holding spells and cardiorespiratory control. Smokers have weak positive expectancies for nicotine replacement therapies relative to smoking (Juliano and Brandon, Nicotine Tob Res, 6:569-574, 2004). Little information is available regarding current practice in continuous renal replacement therapy (CRRT) for the treatment of acute renal failure (ARF) and the possible clinical effect of practice variation. Overextended RNA:DNA hybrid as a negative regulator of RNA polymerase II processivity. Commentary: going to the people--public health nursing today and tomorrow. Forty root canals were obturated without a root canal sealer and served as positive controls. Therefore, when evaluating suicide risk, assessing character dimensions, especially self-directedness along with depressive mood, a risk factor, will be helpful. In vivo resistance to amodiaquine and pyrimethamine were demonstrated from two isolates.

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This review will highlight the morphological features of these precursor lesions and their relationship to the complex molecular processes involved in their development. Adult T-cell leukemia/lymphoma belongs to the group of mature T-cell malignancies according to the WHO classification. In diabetic patients the improvement in postprandial hyperglycemia produced by somatostatin can be accounted for by its inhibitory action on carbohydrate absorption in the gastrointestinal tract. This study examined the ability of occupational therapists to reliably and accurately analyze data from single-subject designs using visual inspection of graphed data. Proteolytic destruction of many cyclins is induced by a multi-subunit ubiquitin ligase termed the anaphase promoting complex/cyclosome (APC/C).

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The model predictions are consistent with the results of experimental exercise and immobilization studies performed by other investigators. Piwi1 is essential for gametogenesis in antivert alcohol side effects mollusk Chlamys farreri. Adequate protein intake is necessary in renal failure to reduce morbidity. Dendritic cells (DC) are unique in their ability to initiate a primary immune response by the presentation of soluble Ags to T cells. After chronic administration of PTU, thyroid image showed predominant microfollicular hyperplasia and attenuated density of parafollicular cells.

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In this study, we confirmed the presence of a novel protease exhibiting substrate specificity toward Lys-Arg sequence. A historical comparison with the reports in the literature of which we are aware indicated that the hips in our study had a lower rate of acetabular revision and loosening than did those with previous metal-on-metal designs and that they had no more acetabular loosening or osteolysis than did those with metal-on-polyethylene articulations followed for an average of five years. Contrast-enhanced CT scan (CECT) of testes showed testicular mass with ascitis and enlargement of retroperitoneal lymphnodes. Our current knowledge of the organisation and assembly of Ty1 and Ty3 VLPs is reviewed here. The anesthetist must pay particular attention to avoid the consequences of possible intraoperative movement. Induction by ouabain of hemoglobin synthesis in cultured Friend erythroleukemic cells. Aerosol delivery of amphotericin B desoxycholate (Fungizone) and liposomal amphotericin B (AmBisome): aerosol characteristics and in-vivo amphotericin B deposition in rats.

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Combination chemotherapy with carboplatin and etoposide against lung adenocarcinoma in a patient undergoing hemodialysis: a case report. The antigen of hepatitis delta virus: examination of in vitro RNA-binding specificity. The specific activity of the enzyme was 1,207 units per mg of protein for hydrolysis of penicillins and cephalosporins, including cefuroxime, cefotaxime, and aztreonam. Clinical experience using mezlocillin in acute and chronic broncho- pneumonia. Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation. Chronic administration of chlorphentermine to rats resulted in a reduction of body weight compared to a normal control group. Clinical effects of amphetamine and L-DOPA on sexuality and aggression. By argon plasma coagulation (APC), a current is applied to tissues as ionised gas.

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A life course approach yields breakthroughs in understanding food insecurity and obesity among Brazilian females. This article summarizes recent developments in packed column supercritical fluid chromatography. In addition, we fitted an ordinary linear regression model (OLSM) and negative binomial regression model (NBRM) of the relationship between body mass index and the rate of apnea and hypopnea events. Starting from the level of 1972 the development is characterized in view of -- general technical, psychological and economical problems -- completion of the program library and the -- technique of semi-on-line data collection. This results in a reduction in colony size which prevents the identification of primitive versus mature progenitor on the basis of standard criteria of colony size. Recently, gene mutations of ABCA12 were found to underlie Harlequin ichthyosis and lamellar ichthyosis, two devastating skin disorders. This study investigated the potency of individual polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) to reduce hepatic vitamin A in the rat.

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The 29-36 kDa ovarian protein (OP), responsible for transient immunosuppression in the permissive host H. Analysis of the purified conjugate formed between synthetic benzidinediimine and glutathione by proton magnetic resonance spectroscopy demonstrated the product to be 3-(glutathion-S-yl)-benzidine. Eligible studies were randomized trials enrolling children 6 to 12 years old and assessing the impact of educational interventions during 6 months or longer on waist circumference, body mass index (BMI), blood pressure and lipid profile to prevent or treat childhood obesity. The 2856 patients were included because of symptoms compatible with an STD, a history of sexual contact with a person known or duricef cost suspected to have chlamydial infection, a history of a nonexclusive sexual relationship or presentation for an abortion. Nuclear morphometric and DNA content analyses of cancer cells in superficial esophageal cancer with reference to lymph node metastasis. The oxoclusters, covalently anchored to the polymer network, act as metal-organic cross-linkers, thus improving the thermomechanical properties of the resulting hybrid nanoparticles. To assess the effect of intermittent subcutaneous injections of signal-selective parathyroid hormone (PTH) peptide analog on fracture healing in orchiectomized mouse models. A number of novel therapies that are currently under investigation may also offer beta-cell structural and functional protection, including dipeptidyl peptidase IV inhibitors and cannabinoid receptor type 1 blockers.

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The characteristics of uterine contractile function in pregnant women in threatened abortion. The central processes of the DRG cells were activated antidromically by stimulation within the spinal cord so that changes in the excitability of the fibers could be examined following conditioning volleys in muscle and cutaneous nerves. Influence of eccentric actions on the metabolic cost of resistance exercise. These were flushed out by the use of retrograde cold crystalloid cardioplegia. Oncolytic adenovirus armed with shRNA targeting MYCN gene inhibits neuroblastoma cell proliferation and in vivo xenograft tumor growth.

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Secondary psoas actinomycosis: a complication of an intra-uterine contraceptive device. Fifty-three patients with megaloblastic anaemia treated with cyanocobalamin and folic acid have been studied. The molecular composition of tau proteins in the range of 45 kD to 64 kD at birth changed after the first postnatal month to a set of several adult variants of higher molecular weights in the range of 59 kD to 95 kD. The amino acid sequence of the protein contains a lipase consensus sequence in the large subunit symmetrel generic name and a region in the small subunit that is similar to the saposins, cofactors for sphingolipid hydrolases. Effect of experimentally induced calcium deficiency on development, metabolism and liver morphogenesis of the chick embryo. Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus. The aim was also to find what percentage of subjects without neurologic signs or symptoms associated with falling had less than ideal stability. As long as catheters are left in place until anastomotic healing is complete, extravasation of contrast material (implying urine extravasation at the anastomotic site) does not influence the subsequent formation of anastomotic strictures. NA was localized on the surface of tissue culture trypomastigotes and in the Golgi apparatus suggesting that the enzyme is modified post-translationally.

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