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Altraz (Anastrozole)
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Altraz

Altraz is a selective non-steroidal aromatase inhibitor. Aromatase is a protein in your body that produces estrogen, which can promote the growth of some cancer cells. By blocking aromatase, Altraz lowers the body's normal production of estrogen. Without estrogen, some breast cancer cells can't grow.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Remeron, Maxolon, Diflucan, Symmetrel, Avapro, Abilify, Sporanox, Nimotop, Cefpolek, Finster, Jumax, Epicure, Inocid,

Also known as: Anastrozole

Description

Altraz is approved to treat certain types of breast cancer in women who’ve gone through menopause.

What breast cancer is

Breast cancer develops when cells in your breast start to grow and multiply (make more cells) more quickly than usual. With most breast cancers, the abnormal cells are encouraged to grow by the hormone estrogen.

If your breast cancer is stimulated by hormones, such as estrogen, certain tests will show that the cancer cells have receptors (attachment sites) for those hormones. This type of breast cancer is called hormone receptor-positive (HR+).

HR+ cancers can be treated with hormone therapies that lower the estrogen level in your body. And because most breast cancer is HR+, hormone therapies are also sometimes used to treat breast cancer whose receptor status isn’t known.

What Altraz does

Altraz is a hormone therapy that’s used to treat certain forms of breast cancer. It’s a type of drug called an aromatase inhibitor. Altraz works by stopping (inhibiting) the action of an enzyme called aromatase. (Enzymes are certain proteins that help chemical reactions to happen inside your body.)

The aromatase enzyme makes estrogen out of steroid hormones in your body, such as testosterone. Aromatase is found in various tissues, including your brain, fat, and skin.

Before menopause, estrogen is mainly produced by your ovaries. And just a small amount is made by the aromatase enzyme. But after menopause, your ovaries stop producing estrogen. At that point, the aromatase enzyme is the main way that your body makes estrogen. (And in men, estrogen is also mainly produced by the aromatase enzyme.)

By stopping aromatase from working, Altraz lowers the amount of estrogen in your body. This helps to stop estrogen from encouraging breast cancer to grow and spread.

How long does it take to work?

Altraz will start working soon after you begin taking it. But you won’t be able to notice this. Your doctor may order different kinds of tests during your treatment to check and see if the drug is working for you.

Dosage

Usual Adult Dose for Breast Cancer:

Initial dose: 1 mg orally taken once a day Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer) Uses: -Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; -First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer; -Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.

Detailed Altraz dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Altraz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Altraz can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Altraz and other medications

Below are lists of medications that can interact with Altraz. These lists do not contain all the drugs that may interact with Altraz.

Before taking Altraz, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Altraz and tamoxifen

Like Altraz, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Altraz can lower the amount of Altraz in your body. This can make Altraz less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Altraz. However, if recommended by your doctor, it’s fine to take Altraz after you’ve finished taking tamoxifen.

Altraz and drugs that contain estrogen

Taking Altraz with drugs that contain estrogen could make Altraz less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Altraz.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Altraz, talk with your doctor.

Altraz and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Altraz. However, you should still check with your doctor or pharmacist before using any of these products while taking Altraz.

For example, it’s possible that supplements such as red clover or wild yam could make Altraz less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Altraz.

Altraz and foods

There aren’t any foods that are known to interact with Altraz. Talk with your doctor to find out if there are any foods you should avoid during Altraz treatment.

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NLG2 and -3 mRNAs decreased to a smaller degree after SNC than after SNT. Diversity of RuBisCO and ATP citrate lyase genes in soda lake sediments. Heparan sulphate proteoglycan (HSPG) efficiently concentrated secreted APRIL in lesions. The results indicate that neck receptors of one side enhance the excitability of the contralateral soleus motoneurons and depress the ipsilateral ones. Compound 1 was deduced as (24S)-lanosta-7-oxo-8-en-3beta, 24, 25-triol on the basis of spectral analysis (UV, IR, MS, 1H NMR, 13C NMR and 2D NMR). Furthermore, analyses of antigen-binding assay and competitive binding assay indicated that the chimeric antibody possessed specificity and affinity similar to that of its parental murine antibody. Environmental control of phase transition and polyp survival of a massive-outbreaker jellyfish. The results obtained expressed the difference of H(2)O(2) scavenging activity between various tested compounds, and the relationship between function and structure of antioxidants was also discussed in this article. The Emerging Role of Bisphosphonates in the Prevention of Bone Metastases. Echocardiography six months after discontinuation of medication showed regression of mitral regurgitation and the laboratory parameters were also normalized.

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