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Alsartan (Valsartan)
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Alsartan

Alsartan is used in adults and in children 1 year of age and older alone or in combination with other medications to treat high blood pressure. It is also used in adults to treat heart failure (condition in which the heart is unable to pump enough blood to the rest of the body) and to improve survival after a heart attack.

Other names for this medication:
Alsart, Alsartan, Arovan, Codiovan, Combisartan, Cordinate, Cotareg, Disys, Kalpress, Miten, Provas, Ramartan, Sarval, Simultan, Starval, Valcap, Valitazin, Valpresan, Valpress, Valpression, Valsaprex, Valsartan, Valturna, Valzaar, Vartalan, Vasaten

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Also known as: Valsartan

Description

Hydrochlorothiazide is a diuretic (water pill). Valsartan is an angiotensin II receptor blocker (sometimes called an ARB blocker).

Alsartan HCT is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Alsartan HCT is given after other blood pressure medicines did not work or have stopped working.

Dosage

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 40 mg orally twice a day Maintenance dose: 80 to 160 mg twice a day. The dose should be increased to the highest dose tolerated by the patient.

Usual Adult Dose for Hypertension:

Initial dose: 80 to 160 mg orally once a day. Maintenance dose: 80 to 320 mg orally once a day

Usual Adult Dose for Myocardial Infarction:

Initial dose: 20 mg orally twice a day Maintenance dose: The initial dosage may be titrated upward within 7 days to 40 mg twice daily, with subsequent titrations to a target maintenance dose of 160 mg twice a day as tolerated by the patient. If symptomatic hypotension or renal dysfunction occurs, consideration should be given to a dosage reduction. Comment: Valsartan may be initiated as early as 12 hours after a myocardial infarction, and may be given with other standard postmyocardial infarction treatment, including thrombolytics, aspirin, beta blockers, and statins.

Usual Pediatric Dose for Hypertension:

6 to 16 years: Initial dose: 1.3 mg/kg once a day (up to 40 mg) Maintenance dose: up to 2.7 mg/kg (up to 160 mg) once a day titrated according to patient response Comments: If the calculated dosage does not correspond to the available tablet strengths, or if children are unable to swallow tablets, the use of a suspension (which can be prepared from the tablets) is recommended. The valsartan dose may need to be increased if the suspension is replaced by a tablet. No data are available in pediatric patients either undergoing dialysis or with a glomerular filtration rate less than 30 mL/min.

Detailed Alsartan dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alsartan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:

decreased urination or are unable to urinate; or an allergy to sulfa drugs.

If you have diabetes, do not use Alsartan HCT together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Alsartan HCT with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood); liver disease; kidney disease; gallstones; lupus; congestive heart failure; gout, or high levels of uric acid in your blood; asthma or allergies; high cholesterol or triglyceride levels; an allergy to penicillin; glaucoma; or if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Alsartan HCT is not approved for use by anyone younger than 18 years old.

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State Estimation with Sensor Recalibrations and Asynchronous Measurements for MPC of an Artificial Pancreas to Treat T1DM. The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERbeta, and enhances expression of oncogenic cytokine GRO. Endoscopically placed stents: a useful alternative for the management of refractory benign cervical esophageal stenosis. This review summarizes the most recent epidemiological data and advances in research into the pathogenesis, diagnosis and treatment of Clostridium difficile infection (CDI). These results strongly demonstrated that coating stability and drug release patterns can be changed by physicochemical properties of various parameters such as organic solvents, additive, and coating strategy. Inspection and measurement of protections against ionizing radiations. The propose of this study was to describe the imaging findings in four patients with emphysematous pyelonephritis and to perform a review of the literature. Recent work in animals and plants suggests that reactive oxygen species (ROS) control cell proliferation. Pravastatin, a 3-hydroxy-3-methyl-glutharyl coenzyme A inhibitor does not show pleiotropic effects in patients with systemic lupus erythematosus.

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Radiative transfer codes for atmospheric correction and aerosol retrieval: intercomparison study. Measurement of total CO2 in microliter samples of urine and other biological fluids using infrared detection of CO2. Optimization of physicochemical conditions was carried out to achieve maximum decolorization of Reactive Red 31 by fungal pellets. Clinical observations suggest that in neuroendocrine digestive tumors a high intratumoral microvascular density is associated with good prognosis. Extravascular mycotic aneurysm of the intracavernous portion of the internal carotid artery. The lower strip (D, displacement of the handle) was moved in proportion to angular displacement of the handle by a potentiometer coupled to the handle axis. Different tensions exist during respiration within alveolar units, and hence the pulmonary capillaries. Other membranes in the human body can also present significant barriers to drug permeation. Structural details of the glycosyltransferase step of peptidoglycan assembly. We believe that the problem with heterogeneous drug information on this subject is not confined to Norway and that our results should be of international interest.

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A new intraoral bone-conduction device has advantages over existing bone-conduction devices for reducing the auditory deficits associated with single-sided deafness (SSD). The most common malignancy amongst the males being the carcinoma of the lungs and amongst the females, carcinoma of the breast. Both psychotic symptoms and neurocognitive deficits appear to contribute independently to decreased quality of life in schizophrenia. Patients should be provided with information and guidance about the advantages and disadvantages of using herbal products. At the protein level, we depict numerical models about the receptosome, the protein machinery connecting neurotransmitters or growth factors to specific, unique downstream effector proteins. One of the most regularly encountered forms of partial hand loss causing physical, psychosocial and financial burden to an individual is the finger amputation followed by trauma. In this article we analyze quantitatively and discuss in detail a number of reactions that take place on a C3H5 potential. Effects of zinc oxide in an occlusive, adhesive dressing on granulation tissue formation. In this study, to evaluate the HA-coated polymeric micelles as a drug carrier, model drug release from the micelles and cytotoxicity of the micelles were investigated. Strategies to tackle the challenges of external beam radiotherapy for liver tumors.

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