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Alprazan (Alprazolam)

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Alprazan is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprazan, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazan is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Albiz, Alparazole, Alpranex, Alprastan, Alprawin, Alprosym, Alprozam, Altin, Andep, Anxilam, Axnil, Balmusa, Besquil, Deproz, Diprex, Exiten, Hiprazole, Notens, Plxna, Prosanti, Sertakem, Tenan, Tensfree, Viprax, Zolark, Zoldac, Zolyde

Similar Products:
Clarinex, Glucotrol, Trandate, Silagra, Zyprexa, Vivosprin, Glyburide, Glicon, Diamet, Grenis,

Also known as: Alprazolam


Alprazan (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alprazan is used to treat anxiety disorders and anxiety caused by depression.

Alprazan is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alprazan on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprazan XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alprazan for medical reasons, the best way to avoid a Alprazan overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprazan consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazan XR dosage information

Side effects

The most common side effects associated with Alprazan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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Patients were then diagnosed by prostatic needle biopsy and the results compared with the other detection methods. Whether SLE alters left ventricular (LV) structure and function in the absence of valvular and clinical coronary artery disease is unknown. Distribution and hypoxia-regulation of haemocyanin in springtails (Collembola). Thus, present results do not support the concept that the pineal body contains comparatively large amounts of lhrh. Then multiple RHs are built on the basis of the region segmentation result, and the color-spatial similarity between each pixel and each RH is calculated accordingly. Sam68 modulates the proliferation of NPC cells probably by activating Akt/FOXO3a pathway and regulating the cell proliferation-related molecules. We therefore conclude that violent video game effects should remain a societal concern. Thirty-five of the patients were free of any recognizable pathology to account for their amenorrhoea and apparently had a dysfunction of the hypothalamic-pituitary axis.

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This paper therefore reviews such data with special reference to nineteenth-century Britain. These results were discussed in relation to the two theories and models of punishment. The spectrum of imaging findings and microscopic appearances in both patients best fit the diagnosis of intraosseous myelolipoma. An analysis of routine-EEG findings with a view to surgical treatment of epilepsy. Metastatic tumors in the breast: a report of 5 cases and review of the literature. Repetition of the semi-automatic segmentation by the same operator did not influence the quality of the contour or our new MR distribution parameters whereas the skills of the operator influenced only the MR distribution parameters, and the instructions given prior to the segmentation influenced both the quality of the contour and the MR distribution parameters. Indication and timing of cholecystectcomy after endoscopic treatment of bile duct stones is critical, and early cholecystectomy within 3-7 days prevents recurrent biliary events. Here, we present a case of epidermolysis bullosa acquisita in a patient with HIV infection.

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High energy irradiation is produced by a quasi-continuous N2-laser. Measles, immune suppression and vaccination: direct and indirect nonspecific vaccine benefits. Acute and chronic hepatic injury has previously been reported with the use of nitrofurantoin. The use of four rating scales which are little known yet within German speaking countries in demonstrated by means of a psychopharmacological investigation on the clinical effects of Desmethyl-Loxapine. The pathway of olfactory transduction was enriched by OPL- and OSCC-related DEGs. It is not known whether these abnormalities progress over the course of the illness or how they relate to neuropsychologic functioning. The ability of the inhibitor to bind the IGFs has now been confirmed directly using covalent cross-linking techniques.

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At a cell number of 0.5 X 10(6) cells/ml a viscosity of 1.094 centipoise (25degrees C, shear-rate 230 s-1) could be found. We identified several polymorphisms that might potentially affect the risk of CHA among exposed fetuses, which warrants further investigation. Additionally, multiple cytotoxic lymphocyte populations with leukemia lytic activity are induced in AML/IL-2 cultures. It is one of the main functional measures of the effect of disease upon the visual system. The elaborate interplay between ERK1/2 and p38 pathways provides a more sophisticated mechanism for regulating MMP-9 activity in neuroinflammatory diseases.

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Most of those who embrace microdentistry are not unscrupulous opportunists but are probably trying to provide the care that represents the highest quality in their opinion. The colonization of pregnant women by Ureaplasma urealyticum makes a premature birth more likely. Results suggested that farms adopted specific management practices irrespective of certification. We use our modular design strategy to assemble tetrahedral, rectangular, and linear shapes of defined dimensions. Mini-computer of M-6000 type is used as the technical base of the information search system.

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One group prior to orthodontic treatment, one group following completion of active orthodontic treatment and an untreated group. Regional bone mineral density of the football players was compared with age-matched reference norms. Cloning and expression of genomic DNA sequences coding for putative erythrocyte membrane-associated antigens of Plasmodium falciparum. The cardiac intensivists usually are medical doctors with a background in cardiology. However, anatomical and functional preservation of the facial nerve (FN) remains a challenge during this surgery. To reduce mortality and morbidity of open repair, a multimodal approach has gradually evolved by maximizing organ protection. Younger patients undergoing complete resection of stage I-III colon cancer had DSS similar to older patients.

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The clinical presentation is characterized by signs and symptoms of portal hypertension such as ascites and digestive hemorrhage. We now show that certain chemokine gradients have the potential to suppress T cell activation by preventing formation of the immunological synapse, the specialized cell-cell junction that forms before a T cell can be fully activated. Comparative study of the specificities of needling acupoints DU20, DU26 and HT7 in intervening vascular dementia in different areas in the brain on the basis of scale assessment and cerebral functional imaging. A rare occurrence of epidermolysis bullosa acquisita in a patient with retroviral disease. Cyst-like spaces were seen histopathologically in the white matter of the cerebellum of the two highest dose groups.

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Effects of aminooxyacetic acid and baclofen on catalepsy, striatal homovanillic acid increase and antinociception caused by methadone in rats. At threshold doses, clorgyline, but not deprenyl or milacemide, increased call duration and decreased call peak frequency compared to vehicle control values. Thymic substance in myasthenia gravis showed inflammatory reaction characterized by presence of neutrophils and macrophages, plasma cell infiltration, epithelial reticular cell hyperplasia, and new germinal center formation. The neuropathologic findings in one patient showed microgliosis and meningovascular involvement of the central nervous system, resulting in two ischemic infarcts in the myelencephalon. Here we investigate the activity of four well-characterized aggregators against three G protein-coupled receptors (GPCRs) recognizing peptide and protein ligands. Measurement of bilirubin-protein conjugates in serum and application to human and rat sera. Eight adult CAH patients with bilateral testicular adrenal rest tumors were treated with testis-sparing surgery. Two patients, catheterized primarily for the preoperative assessment of clinically apparent aortic stenosis and insufficiency, were found to have a patent ductus arteriosus as well at cardiac catheterization. Caffeine significantly affects LH recovery of DEB-treated RAD strain, slightly decreases recovery of rad3 and has almost no effect on survival of rad6.

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Oncogenic mutations in UM involving exons 4 and 5 of GNAQ and GNA11, respectively, were analysed by sequencing. Electrophoretic comparison with glutelins extracted by acetic acid and with hordeins, all reduced and alkylated, discloses a great similitude between this fraction, the glutelins and some hordein fast components alpha, beta and gamma. Earlier and more accurate detection of cardiovascular disease may play an important role. Plain anteroposterior and lateral radiograph were taken preoperatively and postoperatively and during follow-up. Mean depressor response of BP changed in the same way as the conditioning stimulus, while the pressor response changed in the opposite way. The marriage of design and presentation addresses the mechanical and anatomic needs of surgeons in the pelvis, subdiaphragmatic area, and in large and obese patients. This family does not fit any of the recently proposed five subcategories of type II distal arthrogryposis, nor does it fit any other recognized autosomal dominant condition with distal contractures. Solid phase extraction of chromium(VI) from aqueous solutions by adsorption of its diphenylcarbazide complex on an Amberlite XAD-4 resin column. In cryostat sections, neurofilament immunoreactivity was evident between P6 and P13 as a band of staining in the molecular layer indicative of staining of parallel fibres. CEP is a disease wherein photomutilation is a dominant concern and aggressive new approaches of therapy also have been discussed.

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Attempts to treat adult respiratory distress syndrome (ARDS) through modification of inflammatory mediators have been disappointing, and the prognosis remains poor. In summary, these mouse models reveal a broad variety and region-specificity of parenchymal versus vascular cerebral amyloid. Controlling Nutritional Status (CONUT) score is a prognostic marker for gastric cancer patients after curative resection. Synthesis and effect of affinity-labeled analogs and partial sequences of the bradykinin potentiating nonapeptide BPP9 alpha (teprotide). Incorporation of noncomplementary nucleotides at high frequencies by ribodeoxyvirus DNA polymerases and Escherichia coli DNA polymerase I. The revealed differentially changes in protein expression patterns associated with oocyte maturation suggest that several of the examined proteins, such as vitellogenin(Vtg3), protein S100(S100A10), 17-beta hydroxysteroid dehydrogenase(HSD17B1), pentaxin, zona pellucida (ZP3.2), elongation factor1-alpha, caluemnin B, and 14-3-3 protein may play a specific role during zebrafish final oocyte maturation. The start-up time of the CANON process from the activated sludge in the SBBR was 80 d under controlled free ammonia (FA) conditions and sufficient IC source.

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Probing losses of dielectric multilayers by means of Bloch surface waves. Next-generation RNA sequencing (RNA-seq) analyses of corneal endothelium from two PPCD-affected individuals (one with PPCD3 and one of unknown genetic cause) compared with two age-matched controls, and primary human CEnC (pHCEnC) transfected with siRNA-mediated ZEB1 knockdown. It is concluded that the area of greatest potential application of EIT is monitoring cardiopulmonary function, but that studies on much larger groups of patients than have been carried out hitherto are required to fully assess the potential of EIT as a clinical tool. In vivo, highest proliferation of histologically normal mammary epithelium occurs in the progestogenic phase of the menstrual cycle or under the progestogenic influence of oral contraceptives. In Arabidopsis thaliana, CONSTANS (CO) transcription factor plays a central role in regulating photoperiodic flowering. There is growing interest in the role of vitamin C physiological role.

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The development, validation, and adoption of sensitive and discriminatory measures of disease activity is an unmet need that has the potential to transform both drug development and routine clinical care for the patient with uveitis. The two professions have a profound positive impact on animal health, feeding performance, cattle well being, beef quality, and consumer acceptance. In fully condensed, mature sperm nuclei, the telomere sequences appeared as discrete spots of various sizes interspersed throughout the volume of the nuclei. Optimal stopover decisions under wind influence: the effects of correlated winds. Although the two subjects had had diabetes for more than 30 years, there were no signs of diabetic retinopathy. Secondarily, compared to standard care, PIP WLH were more likely to complete tasks to prevent vertical transmission, use one feeding method for 6 months, avoid birth-related medical complications, and have infants with healthy height-for-age measurements. It is not yet known whether calcitriol 25 mcg capsule SMC from AAA tissue exhibit a difference in proliferative capacity compared to SMC from nonaneurysmal vessels or to what extent such differences might be due to aging alone or other patient-specific factors. The former is essential to the support of the pig health care programme in Denmark. Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta.

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The effect of lignocaine (USP: lidocaine) on intramyocardial conduction in ischaemic and nonischaemic areas of the left ventricular myocardium was determined in 11 mongrel dogs. The case presented is a 25-year-old male with a malignant neuroectodermal tumour on the left chest wall (Askin tumour), treated with surgery after neoadyuvant chemotherapy and followed by consolidation chemotherapy. The method combines a 3D PRESTO pulse sequence with the concept of sensitivity-encoding with multiple receiver coils (SENSE). Inhibition of secretion occurred in all three patients, as evidenced by decrease in catheter output, which allowed the catheter to be removed. Repeated administration of citalopram increased the amount of dopamine D2 receptors, the level of dopamine D2 receptor mRNA, and the transcription rate of the dopamine D2 receptor gene. There is evidence for a differential alteration in the concentrations of 3 alpha-reduced neuroactive steroids in major depression. Distraction and reappraisal were used more when regulating for hedonic reasons (e.g., to feel better), but these strategies were also linked to certain instrumental goals (e.g., getting work done).

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Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Sufficient epidemiological information should be available before controlled release technology is implemented. The role of chronic inflammation as a possible contributing factor to anemia in pregnancy has important implications for the clinical evaluation and treatment of women. The ability of a PAF antagonist, BN 52021, to limit myocardial infarct size in rat was assessed. High-dose methylprednisolone in a porcine model of ARDS induced by endotoxemia.

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The five year survival of this group was the same as that of a control group. To study the ocular hypotensive effect of a nonpsychotropic cannabinoid, HU-211 (11 -hydroxy-delta8-tetra-hydrocannabinol, dimethylheptyl), an N-methyl-D-aspartate (NMDA) agonist, in normotensive rabbits. Improving access to dementia services for people from minority ethnic groups. Quality of life, patient satisfaction and cosmetic outcome after breast reconstruction using DIEP flap or expandable breast implant. Using monoclonal anti-bodies of each subset of lymphocytes, immunological distributions of tumour infiltrating lymphocytes (TIL) were evaluated by means of immunohistochemical staining and the peripheral blood lymphocytes (PBL) were evaluated by flow-cytometry. Blood flow through a prosthetic heart valve operating in a ventricular assist device can be subdivided into three phases: a) forward flow through an open valve, b) rapid valve closure, and c) regurgitant back flow through a closed valve. Localization of transferrin on the surface of the human placenta by electron microscopic immunocytochemistry.

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The bath environment, the bathing task, and the older adult can you drink alcohol while taking diflucan 150 mg : a review and future directions for bathing disability research. In this work we described the results that were obtained using various immunodiagnostic assays for the detection of lyme borreliosis. Here, we discuss several pathogenic mechanisms that have been proposed to explain astrocyte-mediated motor neuron death in ALS. A model for chronic perfusion of the liver of ruminants was developed. A meta-analysis on parent training effectiveness for disruptive child behavior. Radiotherapy is effective in preventing post-operative regrowth of non-secreting pituitary adenomas. Evolutionary relationships among group II intron-encoded proteins and identification of a conserved domain that may be related to maturase function.

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These observations demonstrate physiological dissimilarities between vitamin D2 and vitamin D3 in rats which are in accordance with a different metabolism of the two vitamins. Further studies will be required to establish its optimal dosage and schedule of administration. The variant ER transcript is translated into a truncated receptor protein of approximately M(r) 42,000 when expressed in yeast and, more important, in breast tumor cells. Consecutive adults with UTI presenting to our emergency department (ED) were recruited and followed for 30 days. These studies showed that classic treatment was comparable, but they are insufficient as monotherapy. Furthermore, effusion fluid of the joint may be examined for RF, ANA, complement, rhagocytes, crystals, protein content etc.--Among the collagen diseases sensu strictori, systemic lupus erythematosus is the most important.

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The actions of various growth factors on KGF, HGF, and KL expression are examined. Furthermore, following MALL13 stimulation in PRP platelets, the amount of buffer LDH markedly increased and electron microscopy findings showed vacuoles appearing inside the platelets. Persistent primitive hypoglossal artery: an incidental autopsy finding and its significance in clinical practice. It was found that there is significant interspecific and even intraspecific variation in the spontaneous frequency of SCEs. In this review, we aim to provide an update on the epidemiology, pathogenesis, clinical presentation, and management of this challenging extra-articular manifestation. Evaluation of mass examinations of can protonix cause positive drug test pregnant women for syphilis detection using the FTA-ABS reaction with a dried drop of blood.

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Satisfaction with oncology care among patients with advanced cancer and their caregivers. Enhanced intraphagocytic killing of Brucella abortus in bovine mononuclear cells by liposomes-containing gentamicin. Role of gastric acid secretion in progression of acute gastric erosions induced by ischemia-reperfusion into gastric ulcers. Tools to minimize interlaboratory variability in vitellogenin gene expression monitoring programs. Polymorphisms of the UDP-glucuronosyltransferase 1-A1 gene in Tunisian population. Some of the same drugs which cause phototoxic responses occasionally produce photoallergic reactions.

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The psychological development of orphanage-reared infants: interventions with outcomes (Tehran). In a study of the sources of health care news, nurses appeared to be virtually silent: Journalists do not seek out nurses as sources of information on health care. Susceptibility to multiple sclerosis: interplay between genes and environment. Reconstitution of clathrin-coated pit budding from plasma membranes. Learning to Detect Triggers of Airway Symptoms: The Role of Illness Beliefs, Conceptual Categories and Actual Experience with Allergic Symptoms. Limitations of the MANOVA of statistical moments in bioequivalence trials of drugs with slow elimination rate: will klonopin help with alcohol withdrawal a study with spironolactone. Use of the fatigue questionnaire (QFES) in child athletes for individual follow-up: two cases. Selectins belong to the family of adhesion molecules that recognize sugars as ligands through their Carbohydrate Recognition Domain (CRD). These finding, trophoblastic growth and the absence of the chorion were indicative of the ectopic pregnancy.

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Multidisciplinary radiological diagnosis of hepatic angioma in cancer patients. In mosquito cells, growth of SP and WT was similar, but in vivo in Culex pipiens (L.) there were substantial differences. Clinical features associated with a 15.41 Mb deletion of chromosome 13q encompassing the MIR17HG locus. Classification and relationships of rice strains with AA genome by identification of transposable elements at nine loci. Consequently, inferences on the potential effects of presumedly nondifferential exposure misclassification in any given study should only be made after careful sensitivity analyses that take into account the full range of plausible misclassification rates as well as of plausible deviations from nondifferentiality. The purpose of this study was to determine the efficacy of 10 weeks of resistance (RT), functional (FT), or functional plus resistance (FRT) training in older adults who modify tasks of everyday life and are at risk for subsequent disability.

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