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Alprasan (Alprazolam)

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Alprasan is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alprasan is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprasan may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aaram, Aderta, Alpaz, Alpose, Alprac, Alpradol, Alprax, Alzep, Alzolam, Alzolite, Alzom, Anxitab, Anxofit, Aryalam, Ateez, Axnil, Depwell, Dexolam, Ecsit, Elzopam, Endolam, Morecalm, Nexlpra, Norex, Ozolam, Plaxid, Resolin, Resta, Romipraz, Samrox, Selam, Sertakem, Sowel, Sozox, Wycalm, Zenax, Zodia, Zopain, Zopam

Similar Products:
Cozaar, Valtrex, Ceftin, Terramycin, Ultram, Strattera, Trileptal, Bystolic, Starlix, Zudena, Cetzest, Hepravir, Ciprofloxacin, Tenocard, Sinozol, Zolyde, Dumore, Xylonite,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprasan. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprasan XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprasan dosage information

Side effects

The most common side effects associated with Alprasan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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The best comparative methods typically outperform the best single-sequence methods if an alignment of homologous RNA sequences is available. Of the sympathetic ganglia, the superior cervical ganglion (SCG), middle cervical ganglion (MCG) and stellate ganglion (StG) were examined, and of the parasympathetic ganglia, the pterygopalatine ganglion (PpG) and the otic ganglion (OtG) were examined. Multilevel mixed regression models, adjusted for clustering, will be applied to investigate the association between various exposure variables of interest and the longitudinal outcomes, taking into account the correlated data structure and the nesting of observations. In addition to this she showed severe neurological and ocular abnormalities. Acute effects of ambient temperature and particulate air pollution on fractional exhaled nitric oxide: A panel study among diabetic patients in Shanghai, China. Evidence for a role of conditioning in the development of tolerance to morphine-induced inhibition of gastrointestinal transit in rats. PAH was induced in male Sprague-Dawley rats by administering monocrotaline. 49 patients had surgery without IONM while 61 had surgery with IONM.

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Indications for the operation were isolated left main disease or left main equivalents. In the non-pregnant state the mean serum concentrations of zinc and magnesium were lower in IDDM patients than in healthy control women. The agreement was evaluated between the preoperative planning and postoperative actual dose parameters using Bland-Altman analysis. In this review article, we demonstrate and discuss the application of CBTs for psychosomatic problems, including temporomandibular disorders, dental anxiety, burning mouth syndrome, and other oral complaints in dental settings. A comparison of radionuclide methods of evaluating aortic regurgitation with observations on the effect of exercise and symptoms. The gain for higher-order modes up to LP31 is calculated and verified experimentally. Fever had developed after incomplete removal of a pacemaker with the ventricular lead left in situ followed by a new implantation of cardiac stimulation material. Norovirus GII.17 as Major Epidemic Strain in Italy, Winter 2015-16.

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Volume estimation is more sensitive than diameter measurement for detection of aneurysm growth after endovascular aneurysm repair (EVAR), but this has only been confirmed on three-dimensional, reconstructed computer tomography (3-D CT). Oxymetholone treatment in aplastic anaemia: changes in erythropoiesis and serum erythropoietin. Measures of partitioning between sediment, IW, and oligochaetes showed that measured sediment-IW partition coefficients (KTOC ) tended to increase slightly with increasing sediment contamination, whereas the ratio of tissue PCB to IW PCB tended to decrease with increasing concentration in IW. Hysteroscopy is performed often and in many indications but is challenging to learn. Ascorbic acid (VC) deficiency resulted in a decrease in the activities of aminopyrine N-demethylase, aniline hydroxylase, and p-nitroanisole O-demethylase and in the content of cytochrome P-450, as spectrally determined, whereas it caused an increase in the activities of 6 beta-hydroxylases for testosterone and progesterone in liver microsomes of guinea pigs. A mathematical analysis of the mode of action of the inhibitor revealed the progressive establishment of a competition between Dexamethasone and the molecule(s) responsible for the process of attraction. The plasticity of these stromal cells was analyzed using cell culture and histology techniques. Serum progesterone levels were higher in the normal women after the expected day for ovulation. Collective electronic excitations occurring in Na layers grown on Cu(111) and in H2O/Na/Cu(111) have been investigated at room temperature by high resolution electron energy loss spectroscopy.

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Each specimen was then cyclically loaded with 250 N vertical loads applied for 10, 100, 1000, and 10,000 cycles. Chromatographic techniques in plasma, bile, and feces reveal a PCT-specific porphyrin: isocoproporphyrin. When the dynamics of mRNA is assumed to be a fast process (due to faster mRNA degradation than that of protein) we prove that, with appropriate scalings in the burst rate, jump size or translational rate, the bursting phenomena can be transmitted to the slow variable. Trial of oral flupirtine maleate in the treatment of pain after orthopaedic surgery. The central nervous system (CNS) pathology of HTLV-I associated myelopathy or tropical spastic paraparesis (HAM/TSP) is reviewed, based mainly on 12 autopsy cases of Japanese HAM/TSP with a serological confirmation of HTLV-I infection. The development of new ultrasound techniques such as colour power angiography (CPA) and three-dimensional ultrasound may expand the role of ultrasound in the management of the infertile couple. Platelet derived vasoactive mediators may increase vascular permeability and facilitate further deposition of complexes in the tissues. However, re-occlusion often took place, especially in bypasses without flow-limiting lesions. Scale reliability was evaluated by intrarater and interrater variability, internal consistency, and rater agreement.

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Homology modeling study indicated that the hypothetical protein was an unconventional and atypical serine protease belonging to HtrA protein family. Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Endocrine and metabolic diseases: Treatment of infertility and menopausal symptoms. The capacity of educational programs to improve physician performance remains doubtful despite many evaluative efforts. The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells. The ultrastructural changes to the ovaries and oviducts in experimental inflammation under the influence of eplir phonophoresis. In examining the evidence base on daily dialysis according to these ethical criteria, we find that there are not yet sufficient grounds to recommend funding of daily dialysis by the Medicare ESRD Program. Analysis of immunohistochemical and immunogold-stained sponge sections, using light and transmission electron microscopy, revealed latrunculin B labeling mostly beneath the sponge cortex at the border between the external (ectosome) and internal (endosome) layers (ectosome-endosome border). We performed a cross-sectional study of 360 patients attending academic osteoporosis clinics in Toronto, Canada in 2001. Isotope labeling is used to reveal residue-specific information.

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Mechanisms for the modulation of alkylating activity by the quinone group in quinone alkylating agents. Surgical treatment of such fractures should be performed in the shortest possible time after the accident. Although the resumption of low-impact sports activities is compatible with total hip arthroplasty (THA), participation in high-impact sports seems problematic, and there is no consensus as to whether it is advisable. Information has been collected regarding the immediate physiological effects of spaceflight on humans. The recent discovery of checkpoint kinases has suggested the conservation of checkpoint mechanisms between yeast and mammals. its action is immediate, but heparin must be given parenterally. A case of localized amyloidosis of the bladder in a 48-year-old man with painless gross hematuria and evidence of bladder mass on ultrasound is presented. The 3-T systems provide increased signal-to-noise ratio and contrast enhancement (compared with 1.5-T), which can potentially improve spatial resolution and image quality. Problems and countermeasures in the treatment of medullary thyroid carcinoma. The peripheral effects of nociceptin were examined in normal and acutely inflamed rat knee joints by analyzing single unit recordings from articular primary afferents in response to normal and extreme rotation of the knee.

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Airway management for trauma patients with potential cervical spine injuries. Addition of isoproterenol (10 mg/kg) caused a notable rise in ornithine decarboxylase activity and a simultaneous decrease in the amount of the complexed enzyme. Extrapulmonary manifestations of tuberculosis are increasing in incidence. The areas considered in the Workshop were divided into three categories: 1. Management is directed at secondary causes, and general cardiovascular risk reduction is aimed at dietary modification, increased exercise and attainment or maintenance of ideal body weight. A case study is utilized to demonstrate the practicalities inherent in the integrated approach offered. Computerized tomography of talocalcaneal tarsal coalition: a clinical and anatomic study. In 12 months since March, 1975, 25 of 27 patients with tetralogy of Fallot have had corrective operations without ventriculotomy. Abnormal spirometric variables such as the FVC and MVV, likely reflect inspiratory muscle weakness and increased RV likely reflect expiratory muscle weakness. Autism spectrum conditions are diagnosed on the basis of impaired imagination.

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(v) More research is required for understanding the molecular mechanisms responsible for the cytotoxicity of phenothiazines. These results suggest a role for oral loading doses of flecainide in the treatment of acute or symptomatic paroxysmal atrial fibrillation. In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma. Abortion Law and Policy Around the World: In Search of Decriminalization. If hydrops is not present, then the initial impression concerning prognosis may not accurately predict outcome, because there may be marked improvement during fetal life. Most recent bronchoscopies have shown widely patent tracheal lumina in all survivors.

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Nine strains of lactobacilli isolated from different parts of the intestinal tract of chicken were studied to determine their taxonomy and cultural characteristics. Finally, we hypothesized that subpopulations carrying metastasis-related CNAs might be present in both the MPT and LNM. A synthetic gene encoding CD4 amino acid residues 372-433 and a protease cleavage site was cloned into the pTKK19xb/ub plasmid. The tumour parenchyma was primarily made up of fusiform and giant cells. In an attempt to study an effect of cold on endocrine function in man, plasma thyroxine (T4), triiodothyronine (T3), TSH, and cortisol concentrations were studied in 24 healthy men who worked in a cold environment (4 to 6C) for 3 h for the culture of mushrooms and 56 healthy men who lived in cold environment in winter. At this centre, 220 consecutive renal transplants have been studied in patients treated by either CAPD or haemodialysis (HD). All children diagnosed with CD between February 2009 and May 2011 were identified, and those children who had biopsy finding of CD limited to duodenal bulb were reviewed with regard to clinical, serological and histopathological parameters. A solid phase radioimmunoassay procedure has been applied for the determination of glucagon and some variables of the assay procedure were studied. Diagnostic significance of ego and superego blocking situations in the Rosenzweig Picture-Frustration Test. Spontaneous or BCDF-stimulated Ig secretion was of the isotype predominant in vivo, whereas C1q selectively stimulated B cells to produce the other isotype (IgG vs IgM).

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Such antisera are capable of releasing histamine from mast cells, but only in the presence of complement. These D(2) doses were compared with radiography-based ICRU point doses. An association between the presence of asymptomatic renal bacteriuria and intrauterine growth retardation was noted. Diagnostic testing for mild hemophilia a in patients with discrepant one-stage, two-stage, and chromogenic factor VIII:C assays. LGG and HGG appear to have different molecular signatures in genomic variations and our results provide invaluable information for the diagnosis and treatment of gliomas in patients with variable duration or diverse tumor differentiation. Histological examination of cyst wall suggested that the cyst belonged to the group of developmental anomalies of the type of dysraphic intracranial cerebral herniae.

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This study was supported by a research grant from the University of Milan School of Medicine (PUR number 2009-ATE-0570). Their application to an approximate computer model of the cochlea produced a cochlear frequency map consistent with experimental findings. The care situation of patients with interstitial cystitis in Germany: results of a survey of 270 patients. Two plaque-type mutants, a wild strain MB(1), and a slow-growing non-plaque-forming variant of LCM virus were compared in L cell cultures. bri1 was found to predominantly function as a flowering-time enhancer.

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Impact of physical exposure on neck and upper limb disorders in female workers. There was no significant difference in glucagon content between the two groups. A parallel-plate flow cell system was developed to assess individual and combined parameters relevant to oral microbial retention. Questioning evidence for recombination in human mitochondrial DNA. The aim of this report is to describe the periprocedural and early clinical/TEE results from this study. The effect of interferon (IFN) alpha and gamma on cell proliferation was measured and compared to the effect of IFN on the expression of class I and class II major histocompatibility complex (MHC protonix medication classification ) antigens. Psammombodies are dystrophic calcifications with high density in CT being helpful to detect even small metastases. Pain catastrophizing scores were higher in nulliparous than in parous women. Radionuclide lymphography demonstrated several thoracic duct malformations that were confirmed by contrast lymphography.

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Retinol was identified in the lacrimal gland fluid of rabbits and rats, and it is concluded that the lacrimal gland is the source of retinol in the tears. They place an increasingly significant economic burden on healthcare providers as their prevalence is rising in keeping with an aging population. Administration of pentagastrin 6 micrograms/kg subcutaneously increased acid output in all age groups. The salivary glands, larynx, and colon were the most common sites of second tumors after a first salivary cancer. flagyl 500 mg tablets side effects Report from the International Bone Marrow Transplant Registry, 1984. The most common findings on computerized tomography were perirenal hematoma in 29.4 per cent, intrarenal hematoma in 24.7 per cent and parenchymal disruption in 17.6 per cent. The opposing effects of bacterial activity and gas production on anaerobic TCE degradation in soil columns.

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Both patients were referred for assessment of pacing-induced cardiomyopathy with a view to upgrading their device to cardiac resynchronisation therapy (CRT). Sperm morphology and chromatin condensation before and after semen processing. The present study examines the importance of information and offers in medical recruitment ads on application decisions by medical students. Insect cells infected with the recombinant virus produced significant amounts of c-myc protein, which constituted the major phosphoprotein component in these cells. The HUVECs were pretreated with 15d-PGJ2 or ciglitazone (30 microM) for 1 h, followed by a 4-h stimulation with tumor necrosis factor alpha (100 U/mL). The adaptive alpha-spending algorithm incorporates additional contextual evidence (including correlations among genes) about differential expression to adjust the initial p-values to yield the alpha-spending adjusted p-values. The dental-arch surfaces preferentially used in mastication were studied by measuring functional and occlusal surface areas and comparing these to the number of chews required to swallow foods of different texture properties. Important support services include availability and interpretation of computed tomography scans 24 hours everyday and rapid laboratory testing. No differences were found in the incidence of diabetes mellitus type I in the four Catalonian provinces. Those attributes, along with their antecedents and consequences, form a conceptual framework from which a middle-range theory of nurse-administered oral hygiene care is derived that could be tested, evaluated, modified, and translated into practice.

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Up-regulation of monocyte and B-cell co-stimulatory ligands CD4O, B7-1 (CD80) and B7-2 (CD86) were also inhibited in a dose-dependent manner by pdFVIII, but LFA-3 (CD58) was unchanged. The objective of these studies was to evaluate the efficacy of different lotion formulations on facial tissues in preventing irritation, or aiding in the healing of irritation. Branches, after branched or fenestrated aortic repair, appear to be durable and are rarely the cause of patient death. NM and NL neurons arise from distinct precursors of rhombomeres 5 and 6 (R5/R6). Severe toxicity (cytokine release syndrome and side effects of effexor and alcohol neurotoxicity) is the primary constraint to broad implementation of CAR T cell therapy.

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High-risk patients were more susceptible to IVIG-related renal complications. Such shifts in resource supply ratios will alter autotroph stoichiometry, which may in turn have consequences for higher trophic levels, including parasites. Influence of bromocriptine administration to mothers on the development of pup thymocyte and splenocyte subsets and on mitogen-induced proliferation in the mouse. Phase I trials should replace inter-patient by intra-patient dose escalation in order to give each patient a chance to benefit from the treatment. Second, by depleting guanosine nucleotides, MPA suppresses glycosylation and the expression of some adhesion molecules, thereby decreasing the recruitment of lymphocytes and monocytes into sites of inflammation and graft rejection. This report describes surgical access to occluded vein grafts for thrombolysis by direct cutdown where indirect angiographic techniques have failed. Based on the superior cell killing effect with red light, reduced toxicity to the cells in the dark and mild skin reaction with UVA, PC may be a more promising photosensitizer for PDT. The mean number of decayed, missing and filled primary teeth (dmft) in the first group was 1.76 in 2005 and 2.39 in 2006, while the significant caries index increased from 4.79 to 6.35 during this period of time. Utilization of personal and employer-driven safety practices and increased coccidioidomycosis awareness among construction workers should be considered during the planning of any construction work in coccidioidomycosis-endemic regions to prevent occupational infections and outbreaks.

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Immune cell membrane lipids are important determinants of membrane fluidity, eicosanoid production and phagocytosis and fatty acid metabolic abnormalities have been reported in immune cells from patients with multiple sclerosis. Proapoptotic Caspase-9 cannot act as a marker of active seizures and epilepsy. Is chemiluminescent immunoassay an appropriate substitution for radioimmunoassay in monitoring estradiol levels?. Concentrations of each microbial strain, of each organic compound, and of degradation product evolved, as well as specific microbial activities via oxygen uptake tests, were monitored. Improvement of ACTH response to insulin tolerance test in female patients with rheumatoid arthritis due to tumor necrosis factor inhibition. The formalin stability of the epitope may be useful in detecting N. Molecular knowledge about pulp alterations in patients with diabetes could offer new therapeutic directions.

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