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Alpose (Alprazolam)
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Alpose

Alpose is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpose, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpose is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Actirax, Aldip, Almac, Alpam, Alpra, Alpranex, Alprazan, Alprazolam, Alprine, Alzom, Alzonex, Alzotime, Anxigon, Anxizam, Anxorel, Avizolem, Besquil, Betapax, Diprex, Elzopam, Endep, Fludep, Golprax, Hiprazole, Indolam, Kurelam, Luzarn, Niravam, Notence, Oclam, Ozolam, Pronil, Samitol, Selamb, Sertakem, Sinaday, Sinozol, Tancalm, Tenan, Xerodep, Zedep, Zenax, Zocam, Zolam, Zoldac, Zolyde, Zopain, Zopic, Zotam

Similar Products:
Celexa, Ceftin, Zyvox, Eldepryl, Rhinocort, Clarinex, Opidol, Enalind, Benformin, Velpo, Lanzosec, Sildenafilum,

Also known as: Alprazolam

Description

Alpose XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alpose XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alpose XR may also be used for other purposes not listed in this medication guide.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpose dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpose XR dosage information

Side effects

The most common side effects associated with Alpose are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking Alpose, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alpose is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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The European Recombinant Human Chorionic Gonadotrophin Study Group. The aims of this study were to evaluate the severity of untreated carious lesions in a population of asthmatic adults and to evaluate the mediation of socio-economic and oral health behaviour variables. Twenty-one esophageal cancers were used for intra-patient response comparison between the primary disease and the lymph-node metastases. Effects of omeprazole on gastric mucosal growth and differentiation in developing rat. Rapid tumor imaging by active background reduction using biotin-bearing liposomes and avidin. Active immunisation against strong antigens depressed the response. Here we report that an NBS-LRR R protein and its cognate Avr protein form a complex together in the plant cell. We report a new case of primary malignant fibrous histiocytoma of the pancreas in a 72 years old man. Thermotherapy for cancer of the urinary bladder in combination with tegafur suppository and picibanil--concentrations of tegafur in the serum and tissues in bladder carcinoma. To maximize the validity and generalizability of prevalence estimation, we restricted eligibility to general population-based studies (English speaking, 1990 onward) using state- or national-level probability sampling and collecting data directly from older adults.

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Immunostaining revealed that LTA-A attenuated the inflammatory response produced by seizures. Initial drug therapy, including glucose, oxygen and bicarbonate, is intended to restore metabolic homeostasis. Participants performed a semantic judgment task in which they decided whether each word pair conveyed a meaningful expression. By day 4 post-implantation, cancer cells invaded across the diaphragm to the contralateral diaphragmatic surface. Injury to a skeletal muscle belly resulting in discontinuity of the muscle fibers is an infrequent but serious occurrence. Our results suggest that maximal transcriptional activation of the uPA gene by PMA, IL-1 and TNF alpha requires the induction of NFkB activity and the decay of a short lived repressor protein, possibly IkB. If after 1 month a DP less than or equal to 90 mmHg had been reached the patient was reassessed after a further 3 months. However, the roughly equal numbers of patients and controls responding positively to each antigen and the large background variation suggest a lack of biological significance.

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Following vesicular release, the biogenic amine neurotransmitters dopamine, norepinephrine and serotonin are actively cleared from extracellular spaces by presynaptic transporters. Regulation of nitrogen fixation in Rhodospirillum rubrum grown under dark, fermentative conditions. LXA(4) blocked LTD(4)-stimulated phosphatidylinositol 3-kinase (PI 3-kinase) activity in parallel to inhibition of LTD(4)-induced mesangial cell proliferation. The mainstay of treatment is anticoagulation, but given the high mortality associated with some presentations of symptomatic PE, some advocate more aggressive therapy. Metastatic C-cell carcinoma: calcitonin and CEA production in monolayer culture. Radiation doses to members of the public near to Sellafield, Cumbria, from liquid discharges 1952-98. Ultrastructure of intracytoplasmic (cytoplasmic) desmosomes in the squamous cancer cells of the human lung was studied by electron microscopy.

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A study of life insurance claims has permitted a broad multivariate analysis of laboratory and biometric risk factors for cancer mortality in an insured population. The translational functions of the bacterial ribosome are the target for a large number of antimicrobial agents. The treatment of this case was very complicated because of the bleeding from the esophageal varices induced by the anticoagulant therapy for the thrombus. Gastrointestinal damage induced by celecoxib and rofecoxib in rats. Agents, generated both exogenously (environmental radiation, dental X-rays, etc.) and endogenously (reactive oxygen species, DNA replication, V(D)J recombination, etc.), induce numerous DSBs every day. Then the model is extended to multiview network data by maximizing the consistency of the clusters in each view. Eleven patients, eight (8) females and three (3) males aged between 20 and 40 years with a median age of 32 years were treated.

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Recent research has identified abuse victims who lack a perception of themselves as having been abused. DNC is similarly organized to DNI, but the cell crosses the midline in the brain. DCP extracted from serum by affinity-chromatography was analyzed by Western blotting. Biosynthesis of membrane-bound nitrate reductase in Escherichia coli: evidence for a soluble precursor. Diffusion of cancer education information through a Latino community health advisor program. Bacteriophage P22 helps bacteriophage MB78 to overcome the transcription inhibition in rifampicin resistant mutant of Salmonella typhimurium.

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Most of the pulmonary parameters showed statistically significant improvements within the RIMT and control groups, but the improvements were greater in the RIMT group. Association of high plasma TNF-alpha levels and TNF-alpha/IL-10 ratios with TNF2 allele in severe P. Acute post-operative infective endophthalmitis detected on first-day check. We studied the molecular basis of familial Type I hyperlipoproteinemia in two brothers of Turkish descent who had normal plasma apolipoprotein C-II levels and undetectable plasma post-heparin lipoprotein lipase (LPL) activity. Comparative morphological study of the prothallial development in Asplenium species. It was shown that amphetamine treatment did not modify kindling rates when electrodes were situated in the dorsal hippocampus. This fact points to enzymic mechanism involved in elimination of the damaging effect of mutagenic metabolites of the compounds studied.

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Combined results implicate neuroendocrine mechanisms as important factors in the development of lateralization for auditory temporal processing. A genome-wide screening for pathological myopia suggests a novel locus on chromosome 15q12 - 13. Monosomic F1 plants were allowed to self-pollinate and to produce F2 seeds. The effect of weak acid anions on the selective catalytic wet air oxidation of aqueous ammonia to nitrogen. Automatic analysis of some sulfanilamides in therapeutic preparations with the aid of liquid chromatography. Early mucosal changes in dimethylhydrazine (DMH)-induced colonic carcinogenesis were investigated in 12 rats. De novo transcriptome sequencing in Frankliniella occidentalis to identify genes involved in plant virus transmission and insecticide resistance. Because agr signaling mediates a phenotypic change in this pathogen from an adherent colonizing phenotype to one associated with considerable tissue injury and invasiveness, we postulated that a significant contribution to host defense against tissue damaging and invasive infections could be provided by innate immune mechanisms that antagonize agr signaling.

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It is concluded that most probably the growth-promoting effect of antibiotics is obtained by way of an eradication of the bacterial flora harboured in the vagina. Calcitonin gene-related peptide inhibits spontaneous contractions in human uterus and fallopian tube. Characterization of rat liver microsome proteins during development. To specifically target malignant cells, cancer gene therapy needs to combine highly selective gene delivery with highly specific gene expression. CT angiographic data were reconstructed with shaded surface display (SSD) and maximum-intensity projection (MIP). Despite the fact that the reduction of absolute dermal perfusion and improper distribution of perfusion in ischemic feet, primarily diminished perfusion or even a complete loss of blood flow in nutritional capillaries, rather than arterial occlusion per se, is the eventual reason for critical limb ischemia symptoms, the vessels of the microcirculation are not routinely assessed in clinical practice.

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LncRNA TUG1, a tumor oncogene associated with various human cancers, has been reported to be involved in regulating various cellular processes, such as proliferation, apoptosis and invasion through targeting multiple genes. 0.6 T MR imaging of the cervical spine: multislice and multiecho techniques. The wild-type FPP synthase reaction of HOGPP (and CH(3)OGPP) with isopentenyl diphosphate (IPP) gave hydroxyfarnesyl- (and methoxyfarnesyl-) diphosphates that stopped at the first stage of condensation. To be diabetogenic, ppins-specific CD8 T cells had to express IFN-gamma. This may be a mechanical, nonautonomic cause of orthostatic intolerance. Comparison of ranging behaviour in a multi-species complex of free-ranging hosts of bovine tuberculosis in relation to their use as disease sentinels. Respiratory arrest produced by anticoagulant-induced haemorrhage into parapharyngeal space. Substitution of residues diverging between the alpha and beta subunits identified combinations of sequence motifs determining subunit stoichiometry. A Retrospective, Longitudinal, Claims-Based Comparison of Concomitant Diagnoses Between Individuals with and Without Down Syndrome.

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Survival of spray-dried and free-cells of potential probiotic Lactobacillus plantarum 564 in soft goat cheese. Streptavidin-biotin immunotoxins: a new approach to purging bone marrow. In this article, we aim to provide oncologists with models for CM integration within supportive care. Effects of superstructure type and design on force transmission via implant-stabilised mandibular prostheses. The evidence linking hyperinsulinaemia to the cardiovascular complications and diabetes is suggestive but incomplete and much more information on predictive factors for arterial disease in diabetes is urgently required. Bioreactor for the study of defined interactions of toxic metals and biofilms. There is little guidance in the literature for those seeking to publish program evaluation studies and innovation papers.

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We conducted a retrospective analysis of a multi-institutional breast cancer database for patients treated between 1999 and 2009. However, secondary effects of focal brain injury, such as spreading depression and seizure activity, also have been shown to induce the expression of c-fos. Even from our as yet limited small experiences, its high evaluability and high specificity are promising. Two groups of patients with gastro-intestinal (GI) tumours (41) and recurrent glioblastoma (GBM), (17) underwent radioimmunotherapy after the failure of traditional treatments. A posterior P300 was observed in both tasks as participants encoded information into memory, however the amplitude of the P300 correlated with RT in the spatial task but not in the verbal task. The search for gonadal proteins that regulate pituitary FSH led to the isolation of inhibins and activins. Bile acid and vitamin B12 malabsorption were evaluated in 34 cases of ulcerative colitis. By strategically distributing available frequency channels between the mobile agents and the stationary nodes, the overall network provides reliable long-term communication paths while maximizing data throughput when needed. Possibilities of ovulation induction by pulsatile administration of gonadotropin releasing hormone to women with infertility of hypothalamic origin.

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Labeling of peritoneal macrophages with LPS-gold particles (LPS-Au) at 4 degrees C followed by incubation of the cells at 37 degrees C permits the investigation of LPS endocytosis. The severity of asthma is considered in relation to changes in thyroid function following withdrawal of iodine. Bunyaviruses are negative stranded RNA viruses with a trisegmented genome, and the large, medium, and small RNA segments encode the polymerase, the glycoproteins, and the nucleoprotein, respectively. Balancing autonomy and protection: A qualitative analysis of court hearings dealing with protective measures. Anthropometric and lipid measurements were performed and used to define the hypertriglyceridemic waist phenotype and VAI according to published methods. Salmonella Typhi showed highest susceptibility to Ceftriaxone and does lexapro affect alcohol tolerance Salmonella Paratyphi A to trimethoprim-sulphamethoxazole and Chloramphenicol.

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Limited accuracy for carbon dioxide and a low signal-to-noise ratio together with rapid ageing of electron multipliers were identified as problems still only partially solved. The expressed IL-1-like molecules were characterized by the presence a 60-kd protein for both IL-1alpha-like and IL-1beta-like molecules. The implications of these findings for the use of single-stranded, negative-sense RNA viruses as vectors for vaccines are discussed. The aim of the present study is to investigate which tretinoin brand is best the demographics, aetiologies, complications, treatments and visual outcomes in paediatric uveitis patients in the French-speaking part of Switzerland. HBV prevalence from population-based sero surveys in the APR countries was used to estimate new chronic HBV cases (immigrant arrivals per year with chronic HBV).

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