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Alpkair (Alprazolam)

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Alpkair is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Alcicalm, Alflux, Alltop, Alpaz, Alprazolam, Alzokam, Ambutech, Anilam, Anxorel, Anxyl, Balzam, Cooltime, Cozac, Dazolam, Ecsit, Fledore, Notence, Pizolam, Prozam, Pyrex, Rezolam, Sertakem, Silam, Synozolam, Zopic, Zotin

Similar Products:
Hydrea, Zofran, Zyprexa, Kemadrin, Calan, Otreon, Melitus, Glycurb, Albrodo, Glycomet, Dopezil, Mecotin, Arzyt,

Also known as: Alprazolam


Alpkair XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alpkair XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alpkair XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpkair XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpkair for medical reasons, the best way to avoid a Alpkair overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpkair consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpkair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Altered distribution of 51Cr-labeled mouse lymph node cells pretreated in vitro with lipopolysaccharide. In contrast, the intracellular transport of free heavy chains or peptide-deficient heavy chain-beta 2-microglobulin heterodimers is impaired. The finding may be isolated or associated with complex heart disease. Of the two major classes of CpG-containing oligonucleotides, CpG-A appears restricted to inducing type 1 IFN in innate immune cells and CpG-B to activating B cells to proliferate and produce Abs and inflammatory cytokines. The current investigation examines a recently learned speech motor sequence under dual-task conditions. Most neurosurgical procedures can be conceptualized and segmented into critical task components, which can be simulated independently or in conjunction with other modules to recreate the experience of a complex neurosurgical procedure. Furthermore, intestinal GS mRNA expression was significantly increased by 0.2, 0.4, 0.6, 0.8mM concentrations of glutamine dipeptide in vitro.

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The exploration of novel NRPS products may lead to a better understanding of the chemical communication used by human pathogens and potentially to the discovery of novel therapeutic approaches. Lateral cecal arterial blood flow after xylazine administration was decreased substantially more than was cardiac output, suggesting that xylazine caused constriction of the cecal vasculature. Third, complementary expression patterns for Notch1, Manic, and Lunatic Fringe, as well as Serrate1 and -2 as previously shown (Powell et al., 1998), are progressively established from stage 4 of embryonic development both in the outer root sheath and in the hair matrix. To compare first trimester 2D conventional and 3D power Doppler angiography measures in twins and singletons following assisted reproduction. Fertilizer recommendations are embodied in decision rules, which give a recommended dose of nitrogen (N) as a function of information available at the time the decision is made. This study sought to quantify the incremental cost-effectiveness ratios (ICER) of angiotensin-converting enzyme inhibitor (ACEI), beta-blocker (BB), and aldosterone antagonist (AldA) therapies for patients with heart failure with reduced ejection fraction (HFrEF). Impact of introduction of Bactrocera dorsalis (Diptera: Tephritidae) and classical biological control releases of Fopius arisanus (Hymenoptera: Braconidae) on economically important fruit flies in French Polynesia. Non-immunologic hydrops fetalis--report of 14 cases and literature review.

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This study investigated host factors in children who developed the disease despite conjugate vaccination. Septicemia with this organism usually affects elderly, debilitated patients, who frequently have chronic hepatic disease. Mortality during the first 12 months of life increased with age, presumably because of the decrease of maternally derived measles antibodies. In the present study, 13 subjects repeated several words, which contained extreme consonant and vowel tongue positions, during upright and supine condition. These binding sites appeared not to be coupled to guanine nucleotide-binding proteins, and affinity labeling experiments revealed a specifically labeled protein with an apparent molecular weight of about 100,000. The aim of this study was to evaluate the effects of arterialization of the portal vein on oxygen supply, hepatic energy metabolism and liver regeneration after extended hepatectomy. The repeated measures concordance correlation coefficient was proposed for measuring agreement between two raters or two methods of measuring a response in the presence of repeated measurements (King et al., 2007). No statistically significant increase in serum potassium occurred following succinylcholine, nor were there any ECG changes associated with succinylcholine administration. This article discusses how this emerging knowledge related to schizophrenia affects the nursing care of patients with the disorder.

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Analysis of components of the phosphoinositide 3-kinase pathway revealed expression of phospho-S6 ribosomal protein in cytomegalic neurones. The comparison between a realistic and an idealized gold nanoantenna shows that second harmonic generation is extremely sensitive to asymmetry in the nanostructure shape even in cases where the linear response is barely modified. Antimetabolites like itaconate, which inhibits the isocitrate lyase in A. Cardiac catheterization was performed five patients with one total anomalous pulmonary venous connection and four with partial anomalous pulmonary venous connection. SETTING AND PRACTICE DESCRIPTION: Relevant to community and institutional pharmacists servicing patients with gout. Laboratory experiments for cockroach control with boron preparations. Exonuclease III induced ligase-free directional subcloning of PCR products. Following oral doses, plasma exposures of TGZ were not different between WT and KO rats, and were similar on day 1 and day 7. The primary matching factors were sex, age, initial diagnosis, surgical approach, implantation date and type of implants (bearing size, standard or dual-mobility cup). To validate our method, we perform experiments on the real-world large-scale TRECVID MED 2013 and 2014 data sets and compare our method with several state-of-the-art algorithms.

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The mean value of IGF-1 was 65.9 ng/ml among virus-positive HCC patients, 79.5 ng/ml among virus-negative HCC patients, 110.8 ng/ml among patients with MLC, and 174.7 ng/ml among hospital controls. Targeting antioxidants to mitochondria and cardiovascular diseases: the effects of mitoquinone. We also advance the differential expression of selected genes in the three life cycle stages to explore the potential of RNA-seq for improving knowledge on functional processes along the sponge life cycle. Oleoyl-estrone treatment to late pregnant and mid-lactating rats affects the expression of lipid metabolism genes. This study compared three occlusal examination methods to determine the influence of materials and procedures on the number of tooth contacts recorded. Compared to the GRS infant scales the sensitivity of the ADBB, using the recommended cutoff point of 5 or more, was 0.77 and specificity 0.80.

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Vulnerability of premyelinating oligodendrocytes to white-matter damage in neonatal brain injury. Samples showing negative reaction for the presence of D antigen by Indirect Antiglobulin test were further tested for DEL phenotype by adsorption and elution technique. One possible explanation is that PC subpopulation with metastatic potential may require different level of endogenous androgen or are androgen-independent. It is important for the midwife and the woman to keep in contact in the first six months post partum. Epidermal nevi of her left auricle extended deep into the external ear canal. This retrospective bi-central study involved 98 ONJ patients, 13 of whom were treated with oral bisphosphonates. Understanding these compensatory mechanisms may permit their use to facilitate recovery from trauma or sensory deprivation. pylori-associated gastritis was performed according to the Sydney classification before and after the treatment in 97 patients.

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A model system for tumor invasion of extracellular matrix barriers has been developed, and application of this model has facilitated our understanding of the molecular mechanisms of metastasis formation. Using the derivation for pressure generation, reasons are provided for the varying degree of inflammation found. Rotavirus particles were demonstrated by electron microscopy in the feces of lambs with diarrhea. During maturation granulocytopoietic cells develop intense motility which determines the morphology of the cells on smears. In the absence of periodicity and the presence of quasicrystalline order, the ways that electronic states change remain a mystery. Counterpoint: gamma globulin therapy for children with recurrent respiratory infections.

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Expression of GMP-140 (P-selectin) correlates with graft viability in cold-preserved rat livers. Ficus deltoidea Jack (mistletoe fig) is an ornamental plant found in various parts of the world and used as traditional herbal medicine in some countries. The small animal emergency and critical care veterinarian should have a thorough knowledge of vascular access techniques, including peripheral and central venous catheterization, intraosseous, and arterial access. Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China. It has been found that beta-carotene cleavage products (CarCP), besides having mutagenic and toxic effects on mitochondria due to their prooxidative properties, also initiate spontaneous apoptosis of human neutrophils. Recently, we could report the formation of cationic clusters in pure ionic liquids. Patients were followed up for 57 to 128 months (mean, 85 months). In contrast, in rare cases, spontaneous regression or differentiation towards a benign ganglioneuroma are observed. Phosphotungstic acid hematoxylin stain revealed cross-striations in the cytoplasm of scattered neoplastic cells. Using retrograde approaches with either single or double balloons, successful dilatation can be readily achieved, but with little control of balloon position across the valve.

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Radical resection of certain very low malignant tumours restricted to the bowel wall as well as lymph node staging are possible by this technique. Nickel-titanium orthodontic wires have various temperature-dependent phases. Mechanical strength assessment of a drilled hole in the contralateral cortex at the end of the open wedge for high tibial osteotomy. This will ultimately hinder recognition of chronic HCV in an otherwise easily identifiable, high prevalence group, allowing progression of disease at a time when therapeutic advances make cure a realistic opportunity for many. It is concluded that gelatin as a plasma substitute does not impair the opsonising effect of plasma fibronectin upon the reticuloendothelial system. To evaluate the efficacy, safety, and tolerability of repeated NGX-4010 treatments in the open-label extension phase of a 52-week study in patients with neuropathic pain due to HIV-associated distal sensory polyneuropathy (HIV-DSP).

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In a series of 62 patients with cervical nerve root symptoms CT myelography of the cervical spine revealed specific radiological signs in 24 patients. The melanization response of adult female Aedes aegypti (black-eyed Liverpool strain) against intrathoracically inoculated Dirofilaria immitis microfilariae (mff) was assessed with transmission electron microscopy. However, the amount of 3H-acetylcholine (3H-ACh) was much higher in the striatum, hippocampus and cortex, in particular. The effect of memory blocking antibiotics and norvasc good reviews their analogs on acetylcholinesterase. Physiological principles of ventricular contraction from the molecular biology viewpoint. We studied IGFBP transcripts in C2C12 cell cultures and in adult control and denervated gastrocnemius muscle. Capsular thickness was measured with T1-weighted MRI at the upper areola area. Agonist/inositol trisphosphate-induced release of calcium from murine keratinocytes: a possible link with keratinocyte differentiation. Spectrum of normal and abnormal CT appearances of the ileocecal valve and cecum with endoscopic and surgical correlation.

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At baseline, no significant difference between controls and patients was observed, except for eosinophils. To evaluate intraocular pressure (IOP) control after extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PCIOL) implantation in patients with capsular glaucoma (CG) and coexisting cataract. In the method, the down-slope component of gravity acting on a mass on an inclined plane is used as a static force. Clinical parameters (body mass index and age) are the best predictors for the need of insulin therapy during the first 18 months of diabetes mellitus in young adult patients. At autopsy, a papillary adenocarcinoma was located in the right lung.

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It helps to characterize sources of ethnic variability and provides a foundation for predicting ethnic variability in transporter substrate pharmacokinetics. Basic principles of mechanics indicate that intrabolus pressure must be distinguished from the direct contractile squeeze of the circular muscle on the manometric assembly. New instruments and implants for supplementation of the Harrington system. Concurrent neural control of shivering and nonshivering thermogenesis. Use of experiential methods to teach research in a pre-registration nursing curriculum. With practice, most physicians could employ decision analysis to help solve moderately complicated problems at the bedside or in the office. Emotional behavior in those stressed animals were attenuated by anxiolytics like diazepam, a benzodiazepine receptor agonist and buspirone, a serotonin (5-HT) 1A agonist. Immunonephelometric measurement of human plasma apolipoproteins A-I and A-II: an assay performed by consecutive addition of the two antisera to a single specimen. The main aim of lodine 300 mg fiyat this work is to develop a one-step method for the characterization of mixtures of single- and multi-walled carbon nanotubes using a simple and inexpensive tool, a portable Raman spectrometer.

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This study was to examine whether skeletal health deterioration in the hypogonadal situation is a consequence of an alteration in the functional status of peripheral mononuclear cells and its amelioration, if any, by an oil extract of garlic. Complications of surgical treatment of interventricular communications in the infant. The cautious use of t-PA with heparin in patients who are elderly or demented may be advisable. Vascular perfusate--new theolair 250 mg hond source for preparing fibrinolytic agents. Operative cholangiogram can effectively identify incidental choledocholithiasis or anatomic variation in the biliary system that may significantly influence the surgical approach or postoperative management of the patient. Substituent effect of bis(pyridines)iodonium complexes as iodinating reagents: control of the iodocyclization/oxidation process. Capsule structural heterogeneity and antigenic variation in Cryptococcus neoformans.

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Clinically significant infection could be differentiated from peritoneal contamination with Candida by the presence and persistence of fever, peritoneal signs, peripheral leukocytosis, positive peritoneal cultures for Candida, abnormal films of the abdomen and purulent ascitic fluid. Improvements in early diagnosis, wound care, and critical care delivery may be the cause. Review of the literature indicated that other authors had described similar cases but without specifying the methods of data collection. A total of 757 patients were enrolled in 2 prospective multicenter AOSpine studies, which involved 26 international sites. It is strongly recommended that mandatory family violence courses should be incorporated into the dental curriculum, and that dentists recognize the need for multi-disciplinary cooperation when dealing with mistreated older adults. Designs utilising screws through the plate trended towards statistically significant improved stability against plateau displacement relative to utilising screws outside the plate. A functional HECT E3 ligase domain with a conserved temovate dosage catalytic site was identified in the C-terminal region of TRP120, and TRP120 autoubiquitination occurred in vitro in the presence of host UbcH5b/c E2 enzymes. Vertebral artery compression due to spondylosis and hyperflexion of the cervical spine during operation is discussed as a possible pathogenetic mechanism. By constructing and testing subcongenic strains combined with gene-expression assays, we provide evidence for the candidacy of the Yy1 gene - encoding the ubiquitously expressed and multifunctional Yin Yang 1 transcription factor - as responsible. The mechanism of homeostatic regulation of the intracellular concentration of amino acids by active transport systems is discussed on the basis of this transport model.

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