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Afeditab (Nifedipine)

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Afeditab is used to treat high blood pressure or angina (chest pain). For high blood pressure: Afeditab works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Afeditab works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Addos, Adefin, Afeditab, Anpect, Atanaal, Buconif, Cardifen, Carditas, Cisday, Citilat, Cobalat, Cordaflex, Cordalat, Cordilat, Cordipin, Depin, Depine, Emaberin, Fenidina, Ficard, Glopir, Hexadilat, Jutadilat, Milfadin, Nedipin, Nefelid, Nifangin, Nifatenol, Nifebene, Nifecap, Nifecard, Nifecardia, Nifeclair, Nifedipin, Nifedipina, Nifedipine, Nifedipino, Nifedipinum, Nifehexal, Nifelat, Nipidin, Nirena, Sepamit, Tredalat, Vasdalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Afeditab XL. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Afeditab and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Afeditab are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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In regards to workplace physical activity, some men resist what they perceive to be an emphasis on muscled looks, whereas for others it contributes to looking self-confident. Eukaryotic cells have several quality control pathways that rely on translation to detect and degrade defective RNAs. Chromatin immunoprecipitation (ChIP) assays demonstrated that NSPc1, EZH2 and Dnmt1 bind to the promoter of HOXA7, which is frequently hypermethylated in tumors. Detection of residual carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: a study of surgical margins. Adults 50 and older were identified using cluster random sampling in Liwan District, Guangzhou. Otherwise, there was no consensus regarding use of, or indications for, RNS, SLNB, or ART. Acoustical detection of venous stenosis in hemodialysis patients using principal component analysis. Meningitis associated with serial lumbar punctures and post-hemorrhagic hydrocephalus. Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone. Amphotericin B (10 microM) restored the sensitivity of stationary phase cells to dipyridamole, lowering the IC50 value for thymidine incorporation to 0.25 microM.

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The effect of a simple checklist on frequent pre-induction deficiencies. INBREEDING DEPRESSION, NEUTRAL POLYMORPHISM, AND COPULATORY BEHAVIOR IN FRESHWATER SNAILS: A SELF-FERTILIZATION SYNDROME. I develop a stochastic model to simulate community assembly from a random drift of invasions sustaining the dynamics of recruitment following deaths and extinctions. Submental sEMG and hyoid movement during Mendelsohn maneuver, effortful swallow, and expiratory muscle strength training. Computer simulation to determine how rapid anesthetic recovery protocols to decrease the time for emergence or increase the phase I postanesthesia care unit bypass rate affect staffing of an ambulatory surgery center. The splenic red pulp and the hepatic parenchyma were replaced by masses of amyloid. The reflex bronchodilation evoked by phrenic nerve stimulation was unaffected by propranolol or phentolamine but was abolished by atropine. Mother-child human leukocyte antigen (HLA) concordance and maternal HLA homozygosity may increase the risk of vertical transmission of human immunodeficiency virus type 1 (HIV-1) risk by reducing infant immune responses.

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Effect of protein and mineral supplementation on potential locoweed (Astragalus spp.) poisoning in sheep. Government and private programs help some elderly persons receive adequate health care, but more are needed. The correct transformations between the master and slave coordinate frames can then be calculated and updated when the bases of the endoscope or instrument manipulators are moved to new, unknown, positions at any time before or during surgical procedures. The comparison between nursing prescriptions and the interventions proposed by the NIC for the 3 ND studied evidenced there is agreement among them. In contrast to other direct thrombin inhibitors, argatroban upregulates nitric oxide, enhancing its antithrombotic effect, does not generate antibodies, is not susceptible to degradation by proteases and is hepatically cleared. Trans-arterial and trans-venous interventional radiology for an elderly patient with life-threatening pelvic injury after accidental falling due to life-threatening cardiac arrhythmia: a case report.

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CMV seropositivity determines epoetin dose and hemoglobin levels in patients with CKD. We conducted an uncontrolled, before and after, mixed-methods study in eight health facilities in Bo and Kenema Districts during December 2014 and January 2015. Under slit illumination, images of a fluorescent object are captured using an array detector instead of a line detector so that out-of-focus light is recorded and then subtracted from the adjacent images. Realization of systems able to both recruit cells and influence their fate (affecting their processes) represents a new approach for tissue regeneration. ISAP vaccination is a novel tumor vaccine strategy that is designed to co-load the antigen with a TLR agonist enabling efficient Ag presentation. RT-PCR technique was performed for ASPL-TFE3 gene fusion on two tumours with available frozen tissue. In control mice, PPx stimulated beta-cell proliferation and neogenesis and upregulated Foxm1 and several of its known targets (Plk1, Cenp-a, Birc5/Survivin, and Ccnb1) in islets. While such secretary factors as PTHrP and BMP are thought to be involved in Ihh expression, the mechanism of the restricted expression of Ihh is not clear. Its cDNA was present in human umbilical vein endothelial cells and in most tissues as well as in lung cancer cells.

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Different reaction patterns of dopamine content to prenatal exposure to chlorpyrifos in different periods. The spectrum of abnormalities included posttraumatic lesions, tumor, tethered cord, and syringohydromyelia. Study design was the use of ABS and the KT to reach hemostasis for patients undergoing tonsillectomy. DPSC can be obtained non-invasively and collected from long-distances remaining viable during transportation. This is the first large report of borderline resectable PA and includes objective definitions for this stage of disease. Branches of the vascular bed: a first approach using influence area. There are 14 potential binding sites for SOX9, a transcription factor present in cartilage, in the promoter, and in the first intron of DSPG3. Scant literature exists on neurologic manifestations and treatment regimens in childhood APS. We retrospectively assessed the diagnostic yield of in-house PCR method employed for the amplification IS6110 sequences in 2,973 specimens. In general, the perception of acquired clinical competencies in TMD and OP increased with level of education, and the importance of, and satisfaction with, training was highly rated.

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Mitochondrial oxidative activity was determined in glutamate-malate medium, with micromodification of the YSI Model 53 (Yellow Springs, Ohio) oxygen electrode system. 100 college students from an upper-level community nutrition course. Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics. The authors discuss how to prevent flap failure by allowing close observation and strict offloading of the pedicle flap through current external fixation designs. No significantly increased risk of clinically relevant cardiac valve disorders was found in subjects treated with long-term cabergoline therapy at the doses used in endocrine practice. Study the frequency of elevated cTnT in hemodialysis patients and investigated whether cTnT is elevated. In this study, another injury process, impairment of the electron-transfer system, which occurred during reoxygenation of ischemic liver, was studied during reperfusion of cold preserved liver and during cold incubation of isolated rat-liver mitochondria. The NO inhibition of cytochrome oxidase may be involved in the physiological regulation of respiration rate, as indicated by the finding that isolated cells producing NO can regulate cellular respiration by this means, and the finding that inhibition of NO synthase in vivo causes a stimulation of tissue and whole body oxygen consumption. Concomitant with recent technological advances in organelle proteomics, there is a requirement for more rigorous experimental and analysis design planning and description. Influence of vitamin B12 on the coenzyme A content of the liver of chicks.

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Mixed epithelial and stromal tumours of the kidney have a diverse radiographic appearance, indistinguishable from multilocular cystic nephroma and cystic renal cell carcinoma. Iontronics is a newly emerging interdisciplinary concept which bridges electronics and ionics, covering electrochemistry, solid-state physics, electronic engineering, and biological sciences. The solid product, titanium-chromium sludge, can serve as an inorganic pigment in glass and ceramic industry. Genome-wide gene expression profiling characterized the transcriptional networks induced in tolerogenic DCs by Act-A-iTreg cells. The data strongly suggest that dynorphins could be involved in strain differences concerning CCI resistance. We report on a 78-year-old man with an 8-year history of histologically verified Mycosis fungoides. Coherent-light diffraction on random phase screens with fractal properties leads to the formation of speckle patterns with peculiarities in correlation characteristics in the small-scale region.

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To identify the possible target proteins of NG in platelets, two-dimensional gel electrophoresis (2-DE)-based comparative proteomics was performed and proteins altered in expressional level after NG treatment were identified by MALDI-TOF MS/MS. Comment on the episode at Mombello: truths which should have been told. Cotrimoxazole was recommended in the treatment of actinomycetoma, cutaneous nocardiosis, and basidiobolomycosis. Biological systems are inherently stochastic, a fact which is often ignored when simulating genetic circuits. Effects of sodium bicarbonate ingestion on performance and perceptual responses in a laboratory-simulated BMX cycling qualification series. Amongst these, neutral and acidic components, the latter including sulfatide and gangliosides, were identified. Psychiatric morbidity was indicated in around of one-third of the patients. We previously showed that continuous infusion of rotigotine resulted in less dyskinesia than repeated pulsatile rotigotine administration or repeated oral administration of L-DOPA in MPTP-treated marmosets. ARPE-19-mediated collagen gel contraction is a multistep process that requires integrin ligation and activation of the FAK/Src complex.

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Hence, a new transsylvian corridor of exposure was developed using frameless neuronavigation. KRAS mutations appear to be major driver genetic alterations in both liver and pancreatic MCNs. Physician manager responsibility for the tasks was analyzed by calculating the percentage of responsibility and examining the rank tasks within management function categories. A prospective blinded analysis of functional recovery and cell survival in the FMN after crush injury in fenofibrate 145 mg tablet juvenile and adult mice was carried out. The article summarises a thesis on development and testing of a new instrument for pain assessment: Mobilisation-Observation-Behavior-Intensity-Dementia (MOBID-2) pain scale. Maternal pinealectomy eliminated the influence of prenatal photoperiod on testicular and body weights of male pups, suggesting that a product from the maternal pineal gland communicates daylength to the fetus. The glucose tolerance test after cortisone administration in obese and nonobese men. Visual exploration of multidimensional data is a process of isolating and extracting relationships within and between dimensions. In case of sterile necrotizing pancreatitis, nonsurgical conservative treatment and a vaginal delivery should be performed when possible in these patients to reduce the risk of maternal infection.

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This work has been greatly enhanced by the discovery of genetic, neural, and physiologic indicators, which further validate these constellations of symptoms in young children. Receptor-mediated gene delivery using chemically modified chitosan. Differential expressions of essential and nonessential alpha-tubulin genes in Schizosaccharomyces pombe. Cellular locomotion plays a critical role in such normal processes as embryonic development, tissue segregation, as well as the infiltration of fibroblasts and vascular cells during wound repair and the inflammatory responses of the adult immune system. A classic case of tramadol 50mg dosage cats CdLS has been reviewed in this article and we have discussed diagnosis, management, and anticipatory guidance. RapidArc showed to be a solution to WAR treatments offering good dosimetric features with significant logistic improvements compared to IMRT. Current work demonstrates a new method and a new device for simultaneous in vivo measurements of sarcomere imaging and fiber tension. A novel biological finding is the observation that while DeltadinG cells filament in response to MMS they exhibit wild-type sulA expression after exposure. A new fluorescence method for the detection of hexosamines and their separation by means of thin-layer chromatography. Consistently, 13-cis-RA increased the ability of HUVECs to inhibit AA-induced platelet aggregation.

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Chromium recovery from sorption complexes and chitosan regeneration is finally proposed to optimize the whole process. Administration of klonopin generic pics intracoronary nicorandil reduced the occurrence of no-reflow, slow reflow, and reperfusion arrhythmia, and improved the myocardial perfusion grade, TIMI flow during PCI and improved clinical outcomes in patients with acute MI. Initial results indicate a reliable method producing only one output as opposed to best fit approaches that may generate a different output each time. A quantitative study of the effect of cortisone on fibrosis of the liver in rats. Over the past 10 years, significant anatomic, technical, and instrumentation advances have facilitated the exposure and resection of intradural lesions via a fully endoscopic expanded endonasal approach (EEA).

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Fesoterodine improved erectile function and relaxation of isolated strips of rat CC. Mutations of the two tyrosine phosphorylation sites of Abp1 and depolymerization what sleeping medication is better than ambien of the actin cytoskeleton interfered with BCR-induced Abp1 recruitment to the plasma membrane. In Salmonella, the Salmonella pathogenicity island 1 (SPI-1) encodes a type three secretion system, which is required for invasion of host epithelial cells in the small intestine. Benign musculoskeletal tumors generally show a faint uptake of 18F-FDG, and tumor-like conditions also display various uptake patterns of 18F-FDG. Distinct examinations and resulting therapies are depending on the cardiomyopathy phenotype and the severity of the myocardial compromise.

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