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Afdiex (Glibenclamide)
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Afdiex

Afdiex is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Other names for this medication:
Afdiex, Benclamet, Benformin, Betanase, Betrol, Bionil, Codica, Comdiab, Daocon, Daonil, Diabetnil, Diabetrol, Diabnil, Diolin, Duotrol, Eumet, Giclamide, Glibact, Glibenclamide, Glibet, Glifil, Glimsug, Glinil, Glitrac, Glucomin, Gluconil, Glucosafe, Glucosil, Glunil, Glutowin, Glybenclamide, Glybid, Glybonil, Glybovin, Glybovine, Glycurb, Glymep, Iscept, Metclam, Metica, Secrin, Sugatrol, Sugnil, Sugnl, Sugronil, Symet, Triglucored, Triglycomet

Similar Products:
Maxolon, Mestinon, Rogaine, Arcoxia, Benemid, Xanax, Cipro, Elavil, Zyloprim, Glimcare, Abhigra, Quetiapine, Galenamox, Valrelease,

Also known as: Glibenclamide

Description

Afdiex is an oral diabetes medicine that helps control blood sugar levels.

Afdiex is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Afdiex is not for treating type 1 diabetes.

Dosage

Usual Adult Dose for Diabetes Type 2:

Doses provided as Afdiex-metformin -As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 1.25 mg-250 mg orally once a day -Consider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucose (FBG) greater than 200 mg/dL or HbA1c greater than 9% Maintenance Dose: Increase in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose: 10 mg-2000 mg per day -Patients with Inadequate Glycemic Control on a Afdiex (or another Sulfonylurea) and/or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; 5 mg-500 mg dose should not be used as initial therapy due to an increased risk of hypoglycemia; initial doses should be conservative to avoid hypoglycemia largely due to Afdiex and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of Afdiex (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Addition of thiazolidinedione may be appropriate for patients not adequately controlled on Afdiex-metformin; in patients experiencing hypoglycemia, consider reducing the dose of the Afdiex component. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Detailed Afdiex/metformin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A Afdiex overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Afdiex dosage information

Side effects

The most common side effects associated with Afdiex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of Afdiex in the pediatric population. Safety and efficacy have not been established.

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Recent influenza virus A infections in forensic cases of sudden unexplained death. The signature of polarons is evidenced clearly by the observation of a large (12-20 meV) anticrossing for both InAs and GaAs-like quantum dot phonons using resonant Raman spectroscopy. Phenotypic spectrum of neurodegeneration associated with mutations in the PLA2G6 gene (PLAN). Necrotising fasciitis is a rare, life-threatening infection where there is necrosis of fascia, subcutaneous tissues and skin. Rates of hysterectomies in Indian patients on tamoxifen are substantially lower than those of western patients on tamoxifen. The obtained results indicate that spin polarization gives rise to sizable contributions to the hyperfine coupling tensor of copper in all investigated complexes, while the electronic g-tensors of these complexes are only marginally affected by spin polarization and other factors, such as choice of exchange-correlation functional or molecular structures, will have more pronounced impact on the accuracy of the results. The observed expression pattern of DLX5 homeogene extends the proposed site-specific combination of homeogene expression in neural crest derived cells to human specific dentition. Biochemically, TNF-alpha and redox-active iron are suppressed and biliary bile salt toxicity is reduced.

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