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Actalipid (Simvastatin)
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Actalipid

Actalipid is an inexpensive drug used to lower levels of cholesterol and triglycerides in the blood. Actalipid may also reduce the risk of heart attack or stroke in patients with risk factors for heart disease. This drug is slightly more popular than comparable drugs. It is available in generic and brand versions.

Other names for this medication:
Actalipid, Docsimvasta, Dosavastatin, Lipex, Lipinorm, Lodales, Normotherin, Simbastatin, Simgal, Simvastatin, Simvastatina, Simvastatinum, Simvofix, Sinvacor, Sivastin, Statinal, Vasilip, Zocord, Zorced, Zorstat, Zosta, Zostin, Zostine, Zovast, Zovastin, Zovatin, Zurocid

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Also known as: Simvastatin

Description

Actalipid (simvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Actalipid is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Actalipid is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.

Actalipid is used in adults and children who are at least 10 years old.

Dosage

Take Actalipid exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Actalipid is usually taken at bedtime or with an evening meal. If you take this medicine more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Actalipid, you may need frequent blood tests at your doctor's office.

You may need to take Actalipid on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Actalipid is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Actalipid dosage information

Overdose

If you overdose Actalipid and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actalipid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Grapefruit and grapefruit juice may interact with simvastatin and lead to unwanted side effects. Avoid the use of grapefruit products while taking Actalipid.

Avoid eating foods that are high in fat or cholesterol. Actalipid will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

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avium is very often linked with acquired immune deficiency syndrome-associated opportunistic infections. The present study, carried out on isolated tracheal muscle strips of guinea pigs, was designed to explore this controversy. In period I (1978-1979), the supervisory staff were inside the hospital from 07.01 to 17.00 hours, and on call at home from 17.01 to 07.00 hours of the next day, and in period II (1980-1981), the supervisory staff were inside the hospital 24 h a day. Influence of ampicillin, clindamycin, and metronidazole on faecal excretion of short-chain fatty acids in healthy subjects. Formation and stability of vincristine-tubulin complex in kidney cytosols. In the following decade ioMRI and image guided surgery has evolved from an experimental stage into a safe and routinely clinically applied technique. Normalization and improvement of CNS deficits in mice with Hurler syndrome after long-term peripheral delivery of BBB-targeted iduronidase. Thirty patients were enrolled, including 27 patients with stage IV disease, and 11 patients with performance status of 2. IFCC method for creatine kinase (ATP: creatine N-phosphotransferase, EC 2.7.3.2.

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Despite plausible biologic mechanisms linking increased physical activity to decreased risk for renal cancer, few epidemiologic studies have been able to report a clear inverse association between physical activity and renal cancer, and no meta-analysis is available on the topic. These results suggest that the inhibitory effects of TNF on cutaneous tissue repair are mediated in part by IL-1. A Portable, Pressure Driven, Room Temperature Nucleic Acid Extraction and Storage System for Point of Care Molecular Diagnostics. Photo-ionization and photo-excitation of curcumin investigated by laser flash photolysis. There is currently intense interest in unravelling the modus operandi of type I modular polyketide synthases in order to lay the ground work for their use in the combinatorial biosynthesis of new bioactive molecules. In the two peaks pattern, another absorption peak appeared at 670nm, with the absorption shoulder from 350 to 450 nm, and shared the absorption characteristics of phycocyanin and chlorophyll complex protein. About 4 min is required for an exhaustive search of a 1500-base nucleotide sequence against all mammalian sequences (1.2M bases) in Genbank Ver.

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The hyperthyroid cats were diagnosed of about 23,000 cats examined in two internal veterinary clinics Giessen und Munich). The kinetic mechanism and the substrate specificity of liver alcohol dehydrogenase are changed when 3-benzoylpyridine-adenine dinucleotide is used as coenzyme. In this study, a broad investigation of possible causes of DNA degradation during storage was performed, including GC-content of the fragments, long-term storage, rapid freeze-and-thaw experiments, genomic DNA and short DNA fragments of different species, the influence of shear stress and the effect of nuclease remaining after DNA isolation. Previous research has yielded evidence of attentional biases for food-related cues in binge eating disorder (BED) using behavioural measures such as the Stroop and dot probe paradigm. These studies reveal an intricate, multilayered parasite survival strategy involving pseudokinases that regulate multiple active kinase complexes to synergistically thwart innate immunity. Therefore, the model is not active in the usual sense of adding energy to the cochlea. The study investigated the direct effects of tramadol on the coagulation status of women with gynecologic malignancies in vitro. Adult and embryonic skeletal muscle microexplant culture and isolation of skeletal muscle stem cells. Dynamic contrast enhanced magnetic resonance imaging (MRI) has proven to be quite sensitive for the characterization of masses and early response to therapy. Locomotor recovery following subtotal spinal cord lesions in a rat model.

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Factors associated with the suppressiveness of sugarcane soils to plant-parasitic nematodes. The human Tap protein has been proposed to mediate Mason Pfizer monkey virus constitutive transport element (CTE)-dependent nuclear RNA export and may also play a role in global mRNA export. This study assessed incidence, how to use vermox tablets predictive factors, and outcome of Epstein-Barr virus (EBV) DNAemia in 100 recipients of allogeneic hematopoietic stem cell transplant. The findings here suggest that although American Indian children are at higher risk, in general, compared to white children, rural populations in general are experiencing increases in childhood overweight and obesity. Attempts to extract informations on which input descriptors are important using a genetic input selection algorithm failed. Comparative analysis of results of examination and treatment of 54 patients, suffering obturation jaundice syndrome, is presented. Genetic introgression involved multiple exotic source populations of Danubian and Atlantic origin, thus evidencing the negative impact of few decades of stocking. The present results indicate that piperidine can discriminate between the fast transient and slow persistent components of ACh-induced ICl in Aplysia neurons, and also suggest that two components of the desensitization phase of ACh-induced ICl function in an independent manner. A trans-acting mechanism represses the expression of the major transplantation antigens in mouse hybrid thymoma cell lines. Qualitative and quantitative studies of antral and fundic G cells in pernicious anaemia.

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Six patients with calcified transitional cell carcinoma of the renal pelvis were encountered over a 10-year period, and the radiographic features in these cases are presented. Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice. Synthesis, characterization and opto-electrical properties of ternary Zn2SnO4 nanowires. The distribution patterns of hypothalamocerebellar cortical axons resemble those reported for monoaminergic fibers in the cerebellar cortex. The number of patches also increases with increasing the wall selectivity. Towards global benchmarking of food environments and policies to reduce obesity and diet-related non-communicable diseases: design and methods for nation-wide surveys. The article analyzes the incidence of Sarcoma Kaposi in Norway during the period 1957-86 (30 years). Apparent N1m responses were observed despite total absence of the ABR or absence except for small wave I in all patients, although the latency of N1m was delayed in most patients. Resting and reactive hyperemic leg blood flows are significantly reduced in the paretic compared with the nonparetic limb after disabling stroke. Rapid kinetic characterization of glycosyl hydrolases based on oxime derivatization and nanostructure-initiator mass spectrometry (NIMS).

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We conclude that echocardiography eliminates the need for invasive preoperative diagnostic procedures in selected neonates with congenital aortic arch obstruction. Fermentative production of bio-H2 can be a promising technique for concomitant generation of an electron source for hydrogen driven remediation strategies and treatment of organic residue in marine ecosystems. Hemangiomas of spinal nerve roots pose a challenging diagnostic problem. A comparison of the growth characteristics of samples of muscle from 30 patients (including some noroxin drug control samples) indicated that although muscle from younger patients (less than 14 years) regenerated more quickly, the myotubes did not have better differentiation. Post-operative cervical MRI showed a complete removal of the spinal dysraphism, fistula, and intramedullary abscess. Six patients were operated at 15 levels using psoas muscle retraction technique.

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This mechanism likely contributes to the regulation of processes beyond those of female reproduction. Antiplatelet and direct antithrombin agents may be useful in the prophylaxis of IE in humans. Collected data included surgical blood loss, perioperative complications (wound infection, vascular injury, approach-related complications, and neurological injury), need for secondary procedures, microbiological and laboratory results, and efficacy of infection eradication. The first four principal components represented the major axes of variation in foot morphology: low-arched versus high-arched feet, long and narrow versus short and wide feet, the relative length of the hallux, and the relative length of the forefoot. False diagnoses often lead to patients suffering from symptoms for periods of months or even years, which imposes significant limitations on their tramadol cost working and private lives. In this paper we discuss novel MR imaging blood pool agents characterized by new pharmacokinetic properties. The traumatic SAH is the common manifestation of head injury and difficult to make a diagnosis in forensic investigation. Animal studies have indicated since that KW-2149-induced pulmonary toxicity can be prevented by pretreatment with corticosteroids.

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Such a differential regulation of MMP and TIMP by TGF-beta may influence the rate of extracellular matrix (ECM) turnover following tissue injury, induced during myomectomy and Caesarean section, or in leiomyomas during growth. In the influenza H5N1 virus incident in Hong Kong in 1997, viruses that are closely related to H5N1 viruses initially isolated in a severe outbreak of avian influenza in chickens were isolated from humans, signaling the possibility of an incipient pandemic. Histones in chromatin appeared less accessible to carbamoylation than isolated histones. Structure of cell wall lipopolysaccharide from Salmonella typhimurium. Homer protein family regulation in skeletal muscle and neuromuscular adaptation. She had a 2-day history of fever, lower back and abdominal pain, dysuria, and constipation. It has been shown that vasotec brand name EOCs express CD40, whereas platelets represent the major source of its soluble ligand (sCD40L), which impairs EOC function.We aimed to test the hypothesis that the sCD40L/CD40 axis affects the anti-platelet function of EOCs. The cytoplasm was rather eosinophilic, PAS-negative, and stained red or yellow by AZAN. Androgen-dependent nitric oxide release in rat penis correlates with levels of constitutive nitric oxide synthase isoenzymes. Hemi-arthroplasty of the hip followed by ipsilateral fracture of the femoral shaft.

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