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Acetensa (Losartan)

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Acetensa is used to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors. ACE inhibitors, medicine used to lower high blood pressure, are not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to Acetensa.

Other names for this medication:
Acetensa, Angizaar, Aratan, Cartan, Corus, Cosart, Cozaarex, Czartan, Lacine, Lakea, Lepitrin, Logika, Lopress, Losacar, Losan, Losapres, Losardil, Losartas, Losartil, Losium, Lospre, Lostad, Lotim, Mozartan, Nefrotal, Niten, Omnitan, Ozarium, Portiron, Prelow, Psycholanz, Ranlozar, Resilo, Sarlo, Tacicul, Zartan

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Also known as: Losartan


Acetensa (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Acetensa is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Acetensa is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Acetensa 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Acetensa 25 mg, Acetensa 50 mg, and Acetensa 100 mg may also contain carnauba wax.


Take Acetensa tablets orally with or without food. Do not crush or chew it. Take Acetensa once or twice a day at the same time. If you want to achieve most effective results do not stop taking Acetensa suddenly.


If you overdose Acetensa and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Acetensa overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Acetensa are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Acetensa as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Acetensa. Correct volume or salt depletion prior to administration of Acetensa.

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Suppression of NADPH oxidase 2 substantially restores glucose-induced dysfunction of pancreatic NIT-1 cells. Seven-year review of the unit dose system in a private hospital. Subcutaneous emphysema related to air-powder tooth polishing: a report of three cases. High-pressure liquid chromatography of digitoxigenin and its glycosides. Treatment consisted of incision and drainage, incision and drainage with primary fistulotomy, incision and drainage with primary fistulotomy and counter-drainage, and incision and drainage with insertion of seton.

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A second primary malignancy (SPM) is frequently reported in patients with a gastrointestinal neuroendocrine tumour (NET). Vocational adjustment, interests, work values, and career plans of persons with spinal cord injuries. The administration of hCG increased E2 in both the euthyroid and hypothyroid rats at 48 h with significantly more E2 detected in the hypothyroid rats. Dietary intake of total, animal, and vegetable protein and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-NL study. Additionally, the cancer cell line HeLa synthesized both inhibin subunits. Four cases were referred for management of complications and one for medical-legal review. The findings are shown in different cognitive domains, such as executive functions, attention, memory and psychomotor speed. Only immunogold cytochemistry reveals different staining intensity in the two adjoined elements of a vascular pair. Heparin-induced thrombocytopenia (HIT) related to fondaparinux has been rarely reported, although the ability of fondaparinux to cross-react with heparin antibodies has been often a subject of debate.

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Measurement of the pulmonary diffusing capacity for O2 (DO2) by a rebreathing technique in man. An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009. Authors present a review of epidemiology, ethiopathogenesis and current diagnostic approaches of single umbilical artery syndrome (SUA). The relevance of epigenetic mechanisms to formulations of PTSD for the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) is described. To the best of our knowledge, this is the first report of a huge sternal chondroma growing in a pregnant patient. Comparison of the enzyme-linked immunosorbant assay III, recombinant immunoblot third generation assay, and polymerase chain reaction method in the detection of hepatitis C virus infection in haemodialysis patients. Cradle to cradle design initiatives: lessons and opportunities for Prevention through Design (PtD). From 2003.7 to 2007.12, 19 patients with proximal tibial multi-segment comminuted fractures were treated with closed reduction and LISS fixation.

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Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. Microalbuminuria has been used to detect subjects at risk of cardiovascular disease and chronic kidney disease (CKD) in patients with diabetes, those with hypertension, and the general population. The effects of these pharmacological compounds were either facilitative or disruptive, or allowed for recovery from impaired cognitive performance following the activation or blockade of 5-HT1, 5-HT2, 5-HT3 and 5-HT4 receptors. However, EryP circulate throughout the embryo for several days before the first enucleated forms can be identified in the blood. Microwave-assisted synthesis of novel 2,3-dihydro-4-pyridinones. Toll-like receptors (TLRs) have caught the attention of rheumatologists searching for additional therapeutic targets for diseases such as rheumatoid arthritis and systemic lupus erythematosus. Factors influencing resource utilisation for general practice were primarily time and funding. Presently the service is provided only on request of the referring physician. The treatment option was surgical decompression as the initial procedure, with satisfactory outcome.

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Twenty one test subjects exposed to head-down tilt for 120 days were subdivided to four groups: Group 1--nine subjects used as controls, Group 2--three bed rested subjects who performed regular exercises, Group 3--four bed rested subjects who were given selected drugs, including Vitamin F-99 that influenced lipid metabolism, and Group 4--four bed rested subjects who performed regular exercises and received Vitamin F-99. Right atrial chemodectoma with atypical chest pain: a 6-year surgical follow-up. In this review, we discuss the importance of microdomains with emphasis on sphingolipids in brain development and function as well as how disruption of the sphingolipid metabolism (and hence microdomains) contributes to the pathogenesis of several neurological diseases. In quiescent non-vacuolated nucleoli, the transcriptionally inactive internal NAC is a short strand about 900 nm thick that in cross-section appears as heterogeneous fibrillar centres (FCs). Although several strategies have been used to develop vaccines targeting shigellosis, none has been licensed for use outside China.

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Plasma levels of elastase, trypsin and their inhibitors in bile induced pancreatitis in the dog. Advances in diversity profiling and combinatorial series design. Evaluation of a sedative antispasmodic preparation in industrial medical practice. The theoretical results were compared with experimental data already published and the phase veloctiy shows a good agreement for low concentration of scatterers. Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. Developing a self-directed learning center in a community hospital. What academic internal medicine subspecialists identify as important geriatric learning needs for residents: a pilot study. Short photoperiod also increased the total recovered mitochondrial GDP binding, a finding consistent with increased BAT thermogenic capacity.

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The potential consequences of compensatory evolution for the evolution of novel gene functions and in potentially confounding the detection of positively selected genes are explored. The cardiovascular effects, anesthetic effects, and recovery rates were evaluated in racing Greyhounds under barbiturate anesthesia. The staining results demonstrated that the glycoproteins and sulfated complex carbohydrates in developing rat incisor enamel each display a specific distribution pattern. Some data argue for a link between Alzheimer disease and the decrease of estrogen in post-menopausal women. Sarcoidosis is a multisystem, granulomatous disease with occasional cardiac manifestations. Human chromosomal regions enriched in segmental duplications are subject to extensive genomic reorganization. Quantitative methylation-specific tests suggest that not all cells in a glioblastoma with detectable promoter methylation of the O6-methylguanine DNA methyltransferase (MGMT) gene carry a methylated MGMT allele.

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Low-dose extrapolation of radiation health risks: some implications of uncertainty for radiation protection at low doses. We surveyed current practice by posting a 36-item questionnaire to all audiology and hearing therapy staff that we were able to identify as being involved in tinnitus patient care in England. Calcium mobilization and inositol phosphate accumulation assays revealed that both AC-42 and 77-LH-28-1 display high selectivity to activate the M1 mAChR over other mAChR subtypes. bovis, bovine respiratory syncytial virus, bovine parainfluenza virus type 3, and Mannheimia haemolytica. Case series of 10 prepubertal girls with genital lichen sclerosus. First update of the Lebanese guidelines for osteoporosis assessment and treatment. Appreciating and developing compassionate care in an acute hospital setting caring for older people. Cerebral blood flow during treatment for pulmonary hypertension. In chronic hypertension, blood pressure is sufficiently elevated that one might expect an increase in cerebral blood flow and disruption of the BBB. Nutritional problems are common in frail elderly individuals receiving municipal care.

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These results indicate that sudden activation of apoptosis in the trophically stimulated gut epithelium during peak lactation was instrumental for the fatal outcome of the condition, but the primary cause of the motility dysfunction of the bowel was not established. At laparotomy a huge (weight 1530 g, diameter 19 cm) actively bleeding spleen was identified and splenectomy was performed. The studies may have stimulated some practitioners of crisis intervention to incorrectly conclude that those interventions were ineffective. To understand the system of secreted proteins and receptors involved in cell-cell signaling, we produced a comprehensive set of recombinant secreted proteins and the extracellular domains of transmembrane proteins, which constitute most of the protein components of the extracellular space. Two months after the shipwreck, levels of hydrocarbons characteristic of Erika fuel were significantly higher in pyloric ceca and body wall of A. This pattern of ovarian LDLR expression is thought to signify preparation for yolk protein incorporation into the oocyte. We used multivariate generalized estimating equation methods to model dichotomized outcomes, running separate regressions where the outcome was current exposure of the patient to specific medications. The second type of these channels was located at the end of the vessels almost as though woven into the fabric of the muscular fibres. To analyze the expression and relationship between hypoxia inducible factor-1alpha (HIF-1alpha) and carbonic anhydrase IX (CA IX) in nasal polyps, and to explore the role of HIF-1alpha and CA IX in the pathogenesis of nasal polyps.

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Pigmented villonodular synovitis is a chronic inflammatory disease progressing with histological villonodular hyperplasia in synovium, fibrosis and accumulation of hemosiderin. AN EXPERIMENTAL STUDY OF EVOLUTION IN HETEROGENEOUS ENVIRONMENTS: PHENOLOGICAL ADAPTATION BY A BRUCHID BEETLE. The experimental results show that the proposed method works well, offering (error-free) operational rates that are comparable to or better than the highest capacity barcodes known in the literature. Major abnormalities in the coronary arteries may present in the first few months of life or remain dormant until the exertional demands of adolescence unmask symptoms of myocardial ischaemia. Almost all ER patterns are accompanied with the malignant horizontal/descending ST segment morphology suggesting that inferolateral ER is not only associated with an ischaemic SCD but also a non-ischaemic SCD. The distribution pattern of subchondral bone density is considered to highly reflect the stress distribution across a joint under long-term physiologic loading conditions.

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