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Acetensa (Losartan)
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Acetensa

Acetensa is used to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors. ACE inhibitors, medicine used to lower high blood pressure, are not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to Acetensa.

Other names for this medication:
Acetensa, Angizaar, Aratan, Cartan, Corus, Cosart, Cozaarex, Czartan, Lacine, Lakea, Lepitrin, Logika, Lopress, Losacar, Losan, Losapres, Losardil, Losartas, Losartil, Losium, Lospre, Lostad, Lotim, Mozartan, Nefrotal, Niten, Omnitan, Ozarium, Portiron, Prelow, Psycholanz, Ranlozar, Resilo, Sarlo, Tacicul, Zartan

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Also known as: Losartan

Description

Acetensa (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Acetensa is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Acetensa is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Acetensa 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Acetensa 25 mg, Acetensa 50 mg, and Acetensa 100 mg may also contain carnauba wax.

Dosage

Take Acetensa tablets orally with or without food. Do not crush or chew it. Take Acetensa once or twice a day at the same time. If you want to achieve most effective results do not stop taking Acetensa suddenly.

Overdose

If you overdose Acetensa and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Acetensa overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Acetensa are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Acetensa as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Acetensa. Correct volume or salt depletion prior to administration of Acetensa.

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Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. Microalbuminuria has been used to detect subjects at risk of cardiovascular disease and chronic kidney disease (CKD) in patients with diabetes, those with hypertension, and the general population. The effects of these pharmacological compounds were either facilitative or disruptive, or allowed for recovery from impaired cognitive performance following the activation or blockade of 5-HT1, 5-HT2, 5-HT3 and 5-HT4 receptors. However, EryP circulate throughout the embryo for several days before the first enucleated forms can be identified in the blood. Microwave-assisted synthesis of novel 2,3-dihydro-4-pyridinones. Toll-like receptors (TLRs) have caught the attention of rheumatologists searching for additional therapeutic targets for diseases such as rheumatoid arthritis and systemic lupus erythematosus. Factors influencing resource utilisation for general practice were primarily time and funding. Presently the service is provided only on request of the referring physician. The treatment option was surgical decompression as the initial procedure, with satisfactory outcome.

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Twenty one test subjects exposed to head-down tilt for 120 days were subdivided to four groups: Group 1--nine subjects used as controls, Group 2--three bed rested subjects who performed regular exercises, Group 3--four bed rested subjects who were given selected drugs, including Vitamin F-99 that influenced lipid metabolism, and Group 4--four bed rested subjects who performed regular exercises and received Vitamin F-99. Right atrial chemodectoma with atypical chest pain: a 6-year surgical follow-up. In this review, we discuss the importance of microdomains with emphasis on sphingolipids in brain development and function as well as how disruption of the sphingolipid metabolism (and hence microdomains) contributes to the pathogenesis of several neurological diseases. In quiescent non-vacuolated nucleoli, the transcriptionally inactive internal NAC is a short strand about 900 nm thick that in cross-section appears as heterogeneous fibrillar centres (FCs). Although several strategies have been used to develop vaccines targeting shigellosis, none has been licensed for use outside China.

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Plasma levels of elastase, trypsin and their inhibitors in bile induced pancreatitis in the dog. Advances in diversity profiling and combinatorial series design. Evaluation of a sedative antispasmodic preparation in industrial medical practice. The theoretical results were compared with experimental data already published and the phase veloctiy shows a good agreement for low concentration of scatterers. Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. Developing a self-directed learning center in a community hospital. What academic internal medicine subspecialists identify as important geriatric learning needs for residents: a pilot study. Short photoperiod also increased the total recovered mitochondrial GDP binding, a finding consistent with increased BAT thermogenic capacity.

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