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Acepril (Enalapril)
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Acepril

Acepril is used alone or in combination with other medications to treat high blood pressure. It is also used in combination with other medications to treat heart failure. Acepril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

Other names for this medication:
Auspril, Biocronil, Bitensil, Controlvas, Corprilor, Crinoren, Dilvas, Ecaprilat, Ednyt, Enadura, Enaldun, Enalich, Eritril, Eupressin, Fibrosan, Hipoartel, Innovace, Innozide, Kinfil, Lerite, Maxen, Olivin, Pharpril, Prilenap, Rablas, Reniten, Reniveze, Tenaten, Vapresan, Vasopril, Xanef

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Also known as: Enalapril

Description

Acepril (enalapril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Acepril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old.

Acepril is also used to treat congestive heart failure in adults.

Acepril is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Acepril dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acepril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of enalaprilat in the pediatric population. Safety and efficacy have not been established .

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Blood transfusion-related HIV is still common in developing countries like Nigeria especially among high risk children such as those who require repeated blood transfusions. Early diagnosis of congenital hip luxation by ultrasonic examination. Anipamil, at a dose of 0.5 mg/kg twice daily for three days, prior to challenge with collagen (100 micrograms/kg) or arachidonic acid (1.1 mg/kg), was without effect. Efficacy of treatment was the better the earlier infusion was performed after occurence of clinical signs. Similarly, we have also observed that Leishmania PV also recruits Rab5a by upregulating its expression in human PBMC differentiated macrophages. Carbamoyl phosphate is held in the active site of Escherichia coli aspartate transcarbamoylase by a variety of interactions with specific side chains of the enzyme. The role of patient teaching status, controlling for diagnosis-related group, demographic characteristics, and severity of illness. Synthesis and opioid activities of stereoisomers and other D-amino acid analogs of methionine-enkephalin.

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Partial anterior fundoplication was performed with the edges of the myotomy on the right and left sides sutured to the stomach, which covered the myotomy. Finally, the possibility has been demonstrated to identify and (semi)quantify the presence of SWNTs in a mixture containing MWNTs. A protocol for assessing subtraction errors of arterial spin-tagging perfusion techniques in human brain. The indication for resection was its symptomatology without relation to its diameter, and diameter over 5 cm in asymptomatic patients. This review summarizes current ligament balancing techniques in knee arthroplasty to correct varus deformities. The authors show that this difference reflects differences in maternal antibody titer and differences in efficiency of transport of measles immunity across the placenta. Pathology of goats and sheep experimentally infected with Mycoplasma mycoides var. In two patients, intubation was not possible for technical reasons and the procedure was aborted. Extracts containing renal erythropoietic factor (REF) and others which contain renin reportedly enhance erythropoietin (Ep) titers in the plasma of hypoxic nephrectomized rats. We found that CEACAM1 was only expressed in HepG2 cells, which show a unique property for enhanced anchorage-independent growth.

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Morning urine samples were collected from the subjects and then kept frozen until cadmium analysis. Diffusion-tensor MR imaging for evaluation of the efficacy of hyperbaric oxygen therapy in patients with delayed neuropsychiatric syndrome caused by carbon monoxide inhalation. The effect of o-benzoquinones on free radical reactions stimulated in rat liver microsomes was studied by using 14C-labeled CCl4. No side-effect was observed during and after the treatment period. All three anticonvulsants were effective against maximal (tonic extension of the hindlimbs) threshold seizures. coli O157:H7 from frozen foods inoculated with the organism prior to freezing. DNA sequence analysis also showed that a secondary-site suppressor of a temperature-sensitive mutation in the E. Once the diagnosis has been made, a laparotomy is indispensable. A prerequisite for the ultrasonographic prenatal diagnosis of hydrocephalus is knowledge of the normal shape and position of the foetal lateral ventricles as well as of the range of variability between normal and pathological development.

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The binding of hexobarbital and aniline to cytochrome P-450 of liver microsomes from control and phenobarbital-treated rats of different ages. Chondroitin sulphate proteoglycan in the substratum adhesion sites of Balb/c 3T3 cells. For each indentation test, a least-squares-error curve fitting procedure was used to identify a set of biphasic coefficients (aggregate modulus, permeability, Poisson ratio) that closely modeled experimental behavior. Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.

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Indices describing cerebral vascular reactivity or cerebral blood flow autoregulation, derived from intracranial pressure, near-infrared spectroscopy, or transcranial Doppler are reviewed in this manuscript. T-scores obtained using derived measures can be used to benchmark physical function outcomes against the general Dutch adult population. Sedimentation analysis of the solubilized enzyme on a sucrose gradient indicates that it is a multisubunit protein complex. It was concluded that no long-term reproductive and teratological effects of low-dose dietary T-2 toxin were found in this study. The relation between baseline cardiovascular risk factors and clinical events was investigated, during 6 years of follow-up, in 81 HD patients (50 males and 31 females) whose enzymatic activities, concentrations and genetic polymorphisms of PON1 had been determined in a previous study. The dlarp spatio-temporal pattern of transcription in wild-type and homeotic mutant embryos is consistent with a positive regulation by Sex combs reduced and Ultrabithorax in the parasegment 2 ectoderm and the abdominal mesoderm, respectively. New radiodiagnostic methods from the aspects of the dental surgeon. The isolation and characterization of a monoclonal antibody (C5F10) which identifies dividing cells in normal and neoplastic tissues (carcinomas, sarcomas, and lymphoreticular malignancies) in formalin-fixed, paraffin-embedded sections is glucotrol medication described.

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