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Accupain (Tramadol)

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Accupain is used to help relieve moderate to moderately severe pain. Accupain is similar to opioid analgesics. It works in the brain to change how your body feels and responds to pain. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

Other names for this medication:
Anatram, Arrestadol, Axedol, Bludol, Bolodol, Dolmeri, Dolocet, Domaspas, Esgiypyrin, Euphodol, Gemodol, Kamadol, Mobiya, Moludol, Neutram, Nictram, Novadol, Opigesic, Oshdol, Pacadon, Postadol, Siatram, Sigmadol, Stemadol, Supridol, Takol, Tamody, Taxidol, Tramafen, Tramakind, Tramatas, Tramazac, Tramdop, Tramest, Tramoflex, Tramol, Tranzat, Trapidol, Tromar, Ubitdol, Ultraspas, Veeradol

Similar Products:
Loxitane, Maxalt, Valium, Sinequan, Avodart, Klonopin, Zyrtec, Levothroid, Estrace, Nebinex, Healcer, Valtec, Valowin, Acyclovir, Liolid, Durazol, Maintate,

Also known as: Tramadol


Accupain ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Accupain: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Accupain is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Accupain dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Accupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Interactions between SES and age, and NSC and individual social capital were explored. Effect of dose, time, and pulse sequence on hepatic enhancement in rats. Influence of different tripeptides on the stability of the collagen triple helix. Maternal, infant and social factors associated with birthweight. We developed a new technique using hyaluronic gel injection as a spacer to safely move the esophagus away from the high-dose area during interstitial brachytherapy of a mediastinal target close to the esophagus. CH3 dimerizes as CH1-CL, but CH2 has no contact to the second chain. She had a positive family history for migraine and a history of febrile convulsions.

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Isolation and properties of various molecular forms of aequorin. Chemical characteristics of an Ilex Kuding tea polysaccharide and its protective effects against high fructose-induced liver injury and vascular endothelial dysfunction in mice. Ganciclovir prophylaxis was administered to all cytomegalovirus seropositive patients. This paper describes a small tumor with histologic features of Brenner tumor within the wall of the uterus. Short-latency median nerve SEPs and auditory ERPs were also recorded. The Mosan Study Group of Pigmented Tumours facing toward the oligometastatic cutaneous melanoma.

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Treatment of patients with congestive heart failure with coenzyme Q10 in an open trial. Cohort study on respiratory diseases and lung function in schoolchildren in southwest Germany. Adherence to evidence-based antibiotic therapy guidelines for treatment of upper respiratory tract infections (URIs) varies widely among clinicians. Surviving animals did not exhibit visible signs of abnormal development, although the reduced number of pups per litter may have contributed to this apparently normal development. It is postulated that the decrease is due to the formation of a cysteine-glyoxylate adduct, 2-carboxy-4-thiazolidine carboxylate, which prevents glyoxylate being further oxidized to oxalate. These statistical analyses reveal significant differences between the creatinine courses in the single curve types and, in addition, a significant interaction of the curve types with the creatinine courses.

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Lead-containing preparations in the Asian community: a retrospective survey. MR angiography of occlusive disease of the arteries in the head and neck: current concepts. Through optimization, the wavelet function and wavelet packet decomposition levels (L) were selected. Polyamines were cytotoxic to resting lymphocytes in the presence of FCS in a dose-dependent manner. Another method which is gaining popularity is intraarticular injection of anesthetic cocktail during surgery. Changes in testicular fluid production and plasma hormones in the adult rat after testicular 60Co irradiation. Its identification was based on the following evidence: First, the density of the band corresponding to a 35 kDa protein correlated with the proline-binding activity of what happens if you drink alcohol after taking zyrtec cytoplasmic membranes from putP-deficient and putP-amplified strains. We have studied and compared the effects of IgA and IgG immune complexes and concanavalin A (Con A) on human monocyte tumour necrosis factor (TNF) production. Clinics were randomized to the WIC program (standard care group) or the WIC program plus a 12-month primarily internet-based weight loss program (intervention group), including a website with weekly lessons, web diary, instructional videos, computerized feedback, text messages, and monthly face-to-face groups at the WIC clinics.

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